Biosion, Inc. Licenses BSI04702, An Anti-TROP-2 mAb, to OBI Pharma, Inc. for Worldwide Development and Commercialization Rights as an Antibody Drug Conjugate and Other Derivative Products

On December 13, 2021 Biosion, Inc. ("Biosion"), a global, clinical stage biotechnology company, reported that Biosion and OBI Pharma Inc. (4174.TWO) ("OBI Pharma") have signed an exclusive license agreement under which OBI Pharma will be granted a global exclusive license to Biosion’s proprietary anti-Trop2 humanized monoclonal antibody, BSI04702, for developing next generation biologics (Press release, Biosion, DEC 13, 2021, View Source;and-other-derivative-products-301442963.html [SID1234597014]). The license agreement enables OBI Pharma to conduct further preclinical and clinical development, registration, and commercialization of BSI04702 as an Antibody Drug Conjugate and other derivative products. Under the terms of the agreement, OBI Pharma will pay license fees to Biosion, including an upfront payment, future development milestones and net sales royalties. The specific terms of the agreement were not disclosed.

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"Biosion has been driving innovation to deliver breakthrough therapies for cures. The licensing of our anti-TROP-2 mAb to OBI Pharma for global development further exhibits the strength of our discovery engine and proprietary SynTracerTM HT-endocytosis platform to identify superior mAbs, ideal as ADCs" said Dr. Hugh Davis, Chief Operating Officer of Biosion, Inc. and President of Biosion USA. "We are looking forward to partnering with OBI Pharma to advance BSI-04702 into the clinical stage as fast as possible and making a difference for patients worldwide."

BSI04702 was created through Biosion’s proprietary SynTracerTM HT-endocytosis platform, a high-throughput endocytosis screening application that can identify antibody candidates with high internalization rates- a critical parameter for lead antibody success in next generation ADC development.