On March 9, 2022 Immune-Onc Therapeutics, Inc. ("Immune-Onc"), a private, clinical-stage cancer immunotherapy company developing novel biotherapeutics targeting myeloid checkpoints, reported that two abstracts on IO-108, a novel myeloid checkpoint inhibitor targeting Leukocyte Immunoglobulin-Like Receptor B2 (LILRB2, also known as ILT4), were accepted for presentation at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting being held April 8 – 13, 2022 virtually, and in-person, in New Orleans, Louisiana (Press release, Immune-Onc Therapeutics, MAR 9, 2022, View Source [SID1234609825]).

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Details of Immune-Onc’s AACR (Free AACR Whitepaper) 2022 presentations are as follows:

Abstract Number: 601
Title: IO-108, A fully human therapeutic antibody blocking the myeloid checkpoint LILRB2/ILT4, promotes innate and adaptive anti-cancer immunity in preclinical studies
Presentation Time: April 10, 2022, 1:30 PM – 5:00 PM ET
Location: New Orleans Convention Center, Exhibit Halls D-H, Poster Section 38

Abstract Number: CT209
Title: A first-in-human phase 1 trial of IO-108, an antagonist antibody targeting LILRB2 (ILT4), as monotherapy and in combination with pembrolizumab in adult patients with advanced relapsed or refractory solid tumors (NCT05054348)
Presentation Time: April 12, 2022, 9:00 AM – 12:30 PM ET
Location: New Orleans Convention Center, Exhibit Halls D-H, Poster Section 34