On August 18, 2022 Targovax ASA (OSE: TRVX), a clinical stage biotechnology company developing immune activators to target hard-to-treat solid tumors, reported its second quarter and first half year 2022 results (Press release, Targovax, AUG 18, 2022, View Source [SID1234618470]).
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Members of Targovax’s executive management team will give an online presentation to investors, analysts and the press at 10:00 CET today (details below).
FIRST HALF YEAR 2022 HIGHLIGHTS
ONCOS-102
Signed a clinical collaboration agreement with Agenus for PD-1 and CTLA-4 checkpoint inhibitor supply to the upcoming ONCOS-102 phase 2 melanoma trial
CircRNA pipeline program
Established a research collaboration with Prof. Michael Uhlin at Karolinska Institutet in Stockholm, Sweden, for development of circRNA and NextGen ONCOS viruses
Mutant KRAS platform
Signed a clinical supply agreement with Agenus to include the adjuvant QS-21 STIMULON as an immune-stimulatory component of the TG mutant KRAS cancer vaccines
Awarded two prestigious research grants, totaling NOK 18m, towards the TG mutant RAS program from Innovation Norway and the Norwegian Research Council
Entered a collaboration with Oslo University Hospital to test TG01/QS-21 vaccination in a phase 1/2 study in multiple myeloma
Received IND approval from the US FDA to initiate clinical trials with the enhanced TG01/QS-21 vaccine in the USA
Organization
Appointed circRNA discoverer and pioneer Dr Thomas B Hansen as VP of Research to lead the circRNA pipeline research program
Strengthened the executive management team with Dr Lubor Gaal as Chief Financial Officer
Refreshed the Board of Directors with the addition of Dr Raphael Clynes and Mr Thomas Falck
Erik Digman Wiklund, CEO commented: "Looking ahead to the second half of the year and beyond – Targovax is establishing a broad and innovative immunotherapy pipeline designed to generate a rich flow of both clinical and pre-clinical data. Through differentiated combinations ONCOS-102 is in position to separate from the competition in anti-PD-1 refractory melanoma. The collaborative TG01 trials offer additional upside potential for the major unmet medical need in mutant RAS cancers, at low cost to Targovax. We believe the biggest opportunity long-term lies in our pre-clinical circular RNA program, which provides a cutting-edge innovation engine for platform expansion, partnering and future value creation for our shareholders."
Presentation
We invite to a live webcast today at 10.00 CET. You can join the webcast here. It will be possible to submit questions during the presentation.