On September 20, 2022 Alpine Immune Sciences, Inc. (the "Company") and Cowen and Company, LLC ("Cowen") reported that mutually terminated the Sales Agreement (the "Sales Agreement") between the parties dated July 2, 2021 (Filing, 8-K, Alpine Immune Sciences, SEP 20, 2022, View Source [SID1234621331]). The Sales Agreement provided that the Company may sell shares of its common stock, from time to time, for up to $75,000,000 in aggregate sales proceeds, through an "at the market" equity offering program under which Cowen acted as sales agent. No shares of the Company’s common stock were sold under the Sales Agreement that has been terminated.

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The foregoing description of the Sales Agreement is not complete and is qualified in its entirety by reference to the full text of the Sales Agreement, a copy of which is filed as Exhibit 1.1 to the Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission (the "SEC") on July 2, 2021.