On October 12, 2022 Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programed T cell therapies, reported that Moderna (MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has exercised its option to license Autolus’ proprietary binders against an undisclosed immuno-oncology target for the development and commercialization of mRNA therapeutics (Press release, Autolus, OCT 12, 2022, View Source [SID1234621952]).

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This follows an original agreement with Moderna announced on August 2, 2021, granting Moderna an exclusive option to license Autolus’ proprietary binders for up to four immuno-oncology targets for incorporation in certain mRNA therapeutics. On exercise of the option, Autolus has received an option exercise payment and is eligible to receive development and commercial milestone payments for each product successfully commercialized. In addition, Autolus would be entitled to receive royalties on net sales of all products commercialized under the agreement.

"The collaboration with Moderna has been a productive partnership, and it’s great to see this work progressing to the next stage," said Dr. Martin Pule, CSO of Autolus. "The use of our technology in Moderna’s mRNA platform continues to underscore Autolus’ leadership in the development of innovative differentiated binder and cell programming technologies."