On November 3, 2022 CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, reported that it will present a poster on CTX110, its wholly-owned allogeneic CAR-T cell investigational therapy targeting CD19+ B-cell malignancies, at the American Society of Hematology (ASH) (Free ASH Whitepaper) 2022 Annual Meeting, taking place December 10-13, 2022, virtually and at the Ernest N. Morial Convention Center in New Orleans, Louisiana (Press release, CRISPR Therapeutics, NOV 3, 2022, View Source [SID1234622928]).
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The ASH (Free ASH Whitepaper) abstract includes preliminary data from 32 patients with Large B-Cell Lymphoma (LBCL) who have been dosed in the Company’s ongoing Phase 1 CARBON trial evaluating the safety and efficacy of CTX110. The poster presentation will include updated results from the CARBON trial.
The ASH (Free ASH Whitepaper) abstract is now available at www.hematology.org.
Title: CTX110 Allogeneic CRISPR-Cas9–Engineered CAR-T Cells in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL): Results From the Phase 1 Dose Escalation CARBON Study
Session Name: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster III
Session Date: Monday, December 12, 2022
Presentation Time: 6:00 PM – 8:00 PM ET
Abstract Number: 4629
Location: Ernest N. Morial Convention Center, Hall D
About CTX110 and CARBON Trial
CTX110, a wholly owned program of CRISPR Therapeutics, is a healthy donor-derived gene-edited allogeneic CAR-T investigational therapy targeting cluster of differentiation 19, or CD19. CTX110 is being investigated in the ongoing CARBON trial, a Phase 1 single-arm, multi-center, open label clinical trial, CARBON, is designed to assess the safety and efficacy of several dose levels of CTX110 for the treatment of relapsed or refractory B-cell malignancies. CTX110 has been granted Regenerative Medicine Advanced Therapy designation from the FDA.