On November 9, 2022 TILT Biotherapeutics, a clinical-stage biotechnology company developing cancer immunotherapies, reported that the company has opened an office in Boston, to support its increasing US clinical development, partnering and fund-raising activities (Press release, TILT Biotherapeutics, NOV 9, 2022, View Source [SID1234623578]). The current US clinical trials are run in collaboration with MSD, a tradename of Merck & Co., Inc., Rahway, NJ, USA and the Merck-Pfizer-Alliance.
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TILT Biotherapeutics’ CEO, Akseli Hemminki, a cancer clinician who has personally treated hundreds of cancer patients with earlier versions of oncolytic viruses, said, "Boston is at the heart of one of the world’s biggest biotech clusters, and we’re delighted to become part of that vibrant community as we invest in this infrastructure and accelerate towards Phase 2 trials of our innovative armed oncolytic viruses."
TILT Biotherapeutics’ COO, and President of US operations, Aino Kalervo, who is responsible for initiating the US office operations, said "Our newly established US operations will help to drive our US clinical development in this leading global pharmaceutical market, including lining up several new clinical trial centers, building on our work with the Mayo Clinic, and supporting forthcoming IND filings."
John Goldfinch, TILT Biotherapeutics’ newly appointed US Clinical Lead, with over a decade’s phase I to IV clinical operations and program management experience at US life sciences companies including Athenex, said, "I’m delighted to join TILT to help advance our US program of phase I and II clinical trials. We believe our approach will deliver better outcomes for cancer patients."
TILT Biotherapeutics LLC’s new office is at the CIC in Boston, Massachusetts which has been a home for great entrepreneurs leading fast-growing companies since 1999. This follows its collaborations with US pharma partners and leading cancer centers.
The heart of TILT’s innovative approach revolves around the use of cancer cell specific oncolytic adenoviruses, armed with cytokines and other molecules to boost the patient’s T-cell immune response to better enable it to find and destroy cancer cells.