On March 16, 2023 Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA), a clinical stage biopharmaceutical company focused on Artificial Intelligence ("AI")-driven therapeutic drug development for the treatment of fibrotic diseases, including non-alcoholic steatohepatitis ("NASH"), hepatocellular carcinoma ("HCC"), and other chronic diseases, reported that its Chief Executive Officer, Robert Foster, PharmD, PhD, and its Senior Vice President for Clinical Pharmacology and Analytics, Patrick Mayo, PhD, will be presenting during a webinar entitled "How Artificial Intelligence is Changing Drug Discovery" on Thursday, March 23rd at 1:00 p.m. Eastern Time (Press release, Hepion Pharmaceuticals, MAR 16, 2023, View Source [SID1234628896]).
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"We are honored to be invited to participate in this webinar designed to provide a current perspective of the AI landscape and what may lie ahead," commented Dr. Foster. "We are particularly looking forward to highlighting our proprietary AI-POWR platform, which provides integrative, multi-variate, systems-biology bioinformatic and big-data analysis of proprietary pre-clinical and clinical data with publicly available multi-omic databases to facilitate improved drug target selection, clinical study design, and a priori responder analysis."
Dr. Mayo added, "Through AI-POWR, we were able to harness the power of AI and machine learning to combine a vast array of multi-omic data already available in NASH with the data from the Phase 2a ‘AMBITION’ clinical trial of our lead drug candidate, rencofilstat. That resulted in our identification of rencofilstat biomarkers revealing which patients may best respond to our drug candidate. This has already been validated on clinically relevant biomarkers, ALT and ProC3. Data from the Phase 2a study was used to design the ongoing Phase 2b ‘ASCEND-NASH’ trial which is aimed to validate the current biomarkers with other clinically relevant outcomes and liver histopathology. Ultimately, we anticipate this approach could allow for enrichment and de-risking of our Phase 3 study and provide AI-based dosing strategies for the commercial use of rencofilstat in NASH."
The webinar is being co-produced by the American Chemical Society and the Joseph Priestley Society at the Science History Institute. The live webinar is free for all interested parties, but registration via this link is required. Following the event, a webcast archive will be posted on the Company’s website at www.hepionpharma.com under "Events" in the Investors section.