Tvardi Therapeutics Announces Presentation of Data from the Phase 1 Trial of TTI-101, a STAT3 Inhibitor, in Advanced Solid Tumors at the American Society of Clinical Oncology (ASCO) 2023 Annual Meeting

On May 25, 2023 Tvardi Therapeutics, Inc. ("Tvardi") reported that it will publicly present, for the first time, clinical results from the Phase 1 study of TTI-101, a STAT3 inhibitor, in relapsed/refractory patients with advanced solid tumors, at the upcoming American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) 2023 annual meeting taking place June 2-6, 2023 in Chicago, IL (Press release, Tvardi Therapeutics, MAY 25, 2023, View Source [SID1234632082]). The featured oral presentation will highlight the safety, tolerability, and clinical activity of TTI-101 monotherapy.

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Details of the presentation are as follows:
Title and Link: Phase 1 Clinical Trial Evaluating TTI-101, a First-in-Class, Orally Bioavailable, Small Molecule, Inhibitor of STAT3, in Patients with Advanced Solid Tumors
Session Type/Title: Poster Discussion Session – Developmental Therapeutics – Molecularly Targeted Agents and Tumor Biology
Poster Session Display Date and Time: 6/3/2023, 8:00 AM-11:00 AM
Poster Board Number: 216
Poster Discussion Session Date and Time: 6/3/2023, 1:15 PM-2:45 PM
Presenter: Apostolia M. Tsimberidou, M.D., Ph.D.
Abstract number for publication: 3018

"We are excited to share the promising clinical activity of TTI-101 in patients with advanced disease who have few to no available therapeutic options. This data paves the way for targeting STAT3, using TTI-101, in our three ongoing Phase 2 trials in liver cancer, breast cancer, and idiopathic pulmonary fibrosis," said Imran Alibhai, PhD, CEO of Tvardi. "We are thankful for the patients who participated in Tvardi’s Phase 1 trial."

The annual ASCO (Free ASCO Whitepaper) meeting is the largest of its kind, hosting over 40,000 attendees, connecting oncology professionals in industry, academia, regulatory, and patient advocacy organizations from around the world.