On September 6, 2023 Gracell Biotechnologies Inc. ("Gracell" or the "Company", NASDAQ: GRCL), a global clinical-stage biopharmaceutical company dedicated to developing innovative and highly efficacious cell therapies for the treatment of cancer and autoimmune disease, reported that it will present updated, longer-term results from the ongoing investigator-initiated Phase 1 trial in China evaluating FasTCAR-enabled GC012F in transplant-eligible, high-risk patients with newly diagnosed multiple myeloma (NDMM) (Press release, Gracell Biotechnologies, SEP 6, 2023, View Source [SID1234634963]). The findings will be presented in a poster presentation at the 20th International Myeloma Society (IMS) Annual Meeting, taking place September 27-30, 2023, in Athens, Greece and virtually.
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"We look forward to presenting the latest findings from our clinical study evaluating GC012F for patients with newly diagnosed multiple myeloma at this year’s IMS Annual Meeting," said Dr. Wendy Li, Gracell’s Chief Medical Officer. "There remain significant opportunities to improve outcome for front-line high-risk multiple myeloma patients. With a demonstrably impressive safety profile, differentiated BCMA/CD19 dual-targeting design and FasTCAR next-day manufacturing, we believe GC012F is a compelling, innovative candidate to address the unmet needs for this patient population."
Poster presentation details are as follows:
Abstract title: Phase I open-label single-arm study of dual targeting BCMA and CD19 FasTCAR-T cells (GC012F) as first-line therapy for transplant-eligible newly diagnosed high-risk multiple myeloma
Abstract number: P-136
Abstract category: Treatment of Newly Diagnosed Myeloma – Transplant Eligible
Presentation time: 1:30-2:30PM EEST, Wednesday, September 27, 2023
Additional information about the poster and the IMS Annual Meeting is available on the IMS website.
About GC012F
GC012F is Gracell’s FasTCAR-enabled BCMA/CD19 dual-targeting autologous CAR-T cell therapy, which aims to transform cancer and autoimmune disease treatment by driving fast, deep and durable responses with improved safety profile. GC012F is currently being evaluated in clinical studies in multiple hematological cancers as well as autoimmune diseases, and has demonstrated a consistently strong efficacy and safety profile. Gracell has initiated a Phase 1b/2 trial evaluating GC012F for the treatment of relapsed/refractory multiple myeloma in the United States and a Phase 1/2 clinical trial in China is to be commenced imminently. Gracell has also launched an investigator-initiated trial (IIT) evaluating GC012F for the treatment of refractory systemic lupus erythematosus (rSLE).