On September 12, 2023 RS Oncology, a clinical stage biotechnology company developing innovative therapies to eradicate mesothelioma and other diseases, reported the completion of the Phase 1 dose escalation portion of the MITOPE study (NCT05278975) (Press release, RS Oncology, SEP 12, 2023, View Source [SID1234635128]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The United Kingdom-based multicenter study met its primary objective of evaluating the safety and tolerability of RSO-021, a novel irreversible inhibitor of mitochondrial PRX3, in patients with malignant pleural mesothelioma and local disease affecting the lining of the lungs. These patients also had fluid on their lungs due to the cancer, which had failed to respond to at least one prior treatment.

"Concluding Phase 1 is a significant accomplishment towards bringing a potential new therapy to patients suffering from mesothelioma and other cancers of the lung," said Jarrett Duncan, CEO of RS Oncology. "We thank the patients, caregivers, support groups and the clinical hospital teams who are participating and supporting our program around the UK." "We look forward to sharing the full results of Phase 1 at a major cancer conference in 2024, as we continue our progress towards bringing this exciting new treatment to more patients," added George Naumov, COO of RS Oncology.

For additional information about the trial, please visit www.clinicaltrials.gov using the identifier #NCT05278975.