On May 23, 2017 Sophiris Bio Inc. (NASDAQ: SPHS) (the "Company" or "Sophiris"), a late stage clinical biopharmaceutical company developing topsalysin (PRX302) for the treatment of patients with urological diseases, reported that it has received the regulatory clearance for the diluent – the medium in which topsalysin is diluted (Press release, Sophiris Bio, MAY 23, 2017, View Source [SID1234519269]). Clinical sites can now begin dosing eligible patients in a Phase 2b study in localized prostate cancer.

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