On October 22, 2024, vTv Therapeutics LLC ("vTv LLC"), a controlled subsidiary of vTv Therapeutics Inc. (the "Company"), reported to have received notice from OnKure Therapeutics, formerly Reneo Pharmaceuticals, Inc. ("OnKure"), of their intent to terminate the License Agreement between vTv LLC and Reneo Pharmaceuticals, Inc., dated December 21, 2017, as amended December 20, 2021 (the "Agreement") (Filing, 8-K, vTv Therapeutics, OCT 22, 2024, View Source [SID1234647426]). Under the Agreement, the Company had granted OnKure an exclusive, worldwide license to intellectual property pertaining to the Company’s peroxisome proliferator-activated receptor delta (ppar-δ) agonist program. In its notice, OnKure indicated that it had decided to discontinue development of the program. Under the Agreement, the termination will become effective as of January 20, 2025.

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