On May 26, 2017 Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in T-cell therapy to treat cancer, reported an oral presentation, as well as four trials in progress posters, at the 2017 ASCO (Free ASCO Whitepaper) annual meeting in Chicago, Illinois on June 2 through June 6, 2017 (Press release, Adaptimmune, MAY 26, 2017, View Source [SID1234519297]).

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During an oral presentation scheduled for 1:15-1:27 PM CDT on June 5th, Dr. Sandra P. D’Angelo of the Memorial Sloan Kettering Cancer Center will present a full update on Cohorts 1, 2, 3, and 4 from Adaptimmune’s ongoing study of NY-ESO SPEAR T-cells in patients with synovial sarcoma.

The Company will host a webinar / teleconference on June 6th from 8:00–9:00 AM EDT (1:00 -2:00 PM BST) to discuss the updated synovial sarcoma clinical data. Call in details and the webinar link will be made available in the Investors section of Adaptimmune’s website (View Source).

The four trials in progress posters will summarize the study designs for Adaptimmune’s ongoing NY‑ESO trials in myxoid/round cell liposarcoma (MRCLS), ovarian cancer, and non-small cell lung cancer (NSCLC); the Company’s ongoing MAGE-A10 trial in NSCLC, and its MAGE-A10 triple tumor study in patients with head and neck, melanoma, or urothelial "bladder" tumors.

Adaptimmune will also host a corporate exhibition booth in the Oncology Professionals Hall (Booth #5031).

Details regarding the oral presentation and the four trials in progress posters are as follows:

Oral Presentation:
Monday, June 5, 2017
Session: Developmental Therapeutics—Immunotherapy

• Abstract ID: 3000
— Title: "Open label, non-randomized, multi-cohort pilot study of genetically engineered NY-ESO-1 specific NY-ESO-1c259t in HLA-A2+ patients with synovial sarcoma (NCT01343043)"
— Presentation Time: 1:15-1:27 PM CDT
— Location: Hall D1

Trials in Progress Posters:
Monday, June 5, 2017
Session: Developmental Therapeutics—Immunotherapy
Presentation Time: 8:00-11:30 AM CDT
Location: Hall A

• Abstract ID: TPS3094
— Poster Board #: 187b
— Title: "A phase I/IIa, open-label, clinical trial evaluating the safety and efficacy of autologous T-cells expressing enhanced T-cell receptors (TCRs) specific for NY-ESO-1 in patients with recurrent or treatment refractory ovarian cancer (NCT01567891)"


• Abstract ID: TPS3097
— Poster Board #: 189a
— Title: "A pilot study of NY-ESO-1c259 T-cells in subjects with advanced myxoid/round cell liposarcoma (NCT02992743)"


• Abstract ID: TPS3096
— Poster Board #: 188b
— Title: "Two phase I/II open-label clinical trials evaluating the safety and efficacy of autologous T‑cells expressing enhanced TCRs specific for NY-ESO-1 or MAGE-A10 in subjects with stage IIIb or stage IV non-small cell lung cancer (NCT02588612/NCT02592577)"


• Abstract ID: TPS3098
— Poster Board #: 189b
— Title: "A phase I single-arm, open-label clinical trial evaluating safety of MAGE-A10c796T in subjects with advanced or metastatic head and neck, melanoma, or urothelial tumors (NCT02989064)"