On March 12, 2021 Advaxis, Inc. (Nasdaq: ADXS), a clinical-stage biotechnology company focused on the development and commercialization of immunotherapy products, and Precision for Medicine, a specialized services company supporting next generation approaches to drug development and commercialization, reported that they will present data on a) the development of a novel flow immunophenotyping assay to accurately evaluate total PD-1 expression as a pharmacodynamic biomarker during PD-1 blockade treatment with pembrolizumab and b) the correlation of changes in T cell populations with the clinical activity observed in the ongoing ADXS-503 clinical trial, in a poster presentation at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting 2021, taking place virtually from April 10-15, 2021 (Press release, Advaxis, MAR 12, 2021, View Source [SID1234576575]).
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Details on the posters and corresponding abstracts are shown below. All posters will be made available on the conference website on April 10, 2021.
Title: Evaluation of total PD-1 expression using multi-color flow cytometry in metastatic non-small cell lung cancer patients treated with multi-neoantigen vector (ADXS-503) alone and in combination of pembrolizumab to assess T-cell & T-cell memory subsets
Session Category: Immunology
Session Title: Immune Monitoring / Clinical Correlates
Abstract Number: 1671
The full text of the abstract is available on the AACR (Free AACR Whitepaper) Annual Meeting 2021 website.