On October 20, 2021 Alligator Bioscience AB ("Alligator" or the "Company") reported that the Company was notified that the first patient has been dosed in its Phase II clinical trial collaboration with Shanghai Henlius Biotech, Inc. and AbClon, Inc (Press release, Alligator Bioscience, OCT 20, 2021, View Source [SID1234591628]). Alligator out-licensed AC101 to AbClon, Inc. in October 2016. Abclon, Inc. subsequently sub-licensed AC101 in China for clinical development by Shanghai Henlius Biotech Inc. (November 7, 2018 press release).

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"We are happy to see that Henlius Biotech has dosed the first patient dosed with AC101 (HLX22). Previously, the phase I clinical trial demonstrated that HLX22 is well tolerated and has good safety profiles. Phase II will reinforce safety and compare the clinical efficacy in AC101 (HLX22) and placebo group," said Søren Bregenholt, CEO of Alligator Bioscience. "The commencement of dosing in the Phase II study with AC101 (HLX22) is an important step forward for our best-in-class antibodies technologies and partner collaborations."