On March 21, 2022 AnaptysBio, Inc. (Nasdaq: ANAB), a clinical-stage biotechnology company developing first-in-class antibody product candidates focused on emerging immune control mechanisms applicable to inflammation and immuno-oncology indications, reported the appointment of Daniel Faga as interim president and chief executive officer (CEO), effective immediately (Press release, AnaptysBio, MAR 21, 2022, View Source [SID1234610477]). Mr. Faga currently serves on the company’s Board of Directors and will succeed Hamza Suria, who has stepped down from his role as president and CEO and as a board director. Mr. Suria will continue to support the Company in an advisory capacity.
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"We are highly confident in Dan’s leadership, who has extensive corporate strategy and public company experience in leading and advising world-class biopharmaceutical companies," said Jamie Topper, M.D., Ph. D., chairman of AnaptysBio’s Board of Directors. "On behalf of the entire Board, I want to thank Hamza for his contributions to AnaptysBio, including over 10 years of service as our CEO, resulting in a strong scientifically-oriented and financially sound organization that is developing a wholly-owned multi-asset clinical portfolio directed towards inflammatory diseases."
AnaptysBio is continuing to advance the development of its three wholly-owned pipeline programs in the following indications:
Imsidolimab (anti-IL-36R Ab) has demonstrated efficacy and safety in the GALLOP Phase 2 trial in generalized pustular psoriasis (GPP) and enrollment of the GEMINI-1 GPP Phase 3 trial is ongoing. Top-line data from the imsidolimab HARP Phase 2 trial in moderate-to-severe hidradenitis suppurativa is anticipated during the second half of 2022
Rosnilimab (PD-1 agonist Ab) enrollment of the AZURE Phase 2 trial in moderate-to-severe alopecia areata is ongoing
ANB032 (BTLA modulator Ab) healthy volunteer Phase 1 top-line data is anticipated in the second quarter of 2022
"Looking ahead, I am confident in the future of imsidolimab and our pipeline of innovative antibody-based therapies and pleased to help lead AnaptysBio into this next chapter. We look forward to evaluating further clinical data across all three of our clinical stage programs throughout 2022," said Mr. Faga. "In parallel, our Board of Directors will undergo a strategic portfolio review. This will include defining the clinical path forward across a breadth of potential inflammation-focused indications that could be pursued for each of our clinical and preclinical therapeutic antibody programs as well as the optimal deployment of our approximately $615 million in cash as of the end 2021."
Mr. Faga has been a member of AnaptysBio’s board of directors since December 2021. He is a seasoned executive with more than 20 years of industry and advisory experience in the life sciences industry. Most recently, he was the chief operating officer at Mirati Therapeutics responsible for leading the company’s strategy, corporate finance, legal and other business operations. Prior to Mirati, Dan was chief business officer at Spark Therapeutics until its acquisition by Roche. Previously, Dan was a managing director and founding member of Centerview Partner’s healthcare advisory practice. Dan’s earlier experience includes healthcare investment banking at Merrill Lynch and management consulting in the life sciences practice at PRTM. Dan has earned a B.S. in engineering from Cornell University and an M.B.A. in healthcare management from the Wharton School of the University of Pennsylvania.