On March 9, 2022 Anaveon, a clinical-stage immuno-oncology company, reported that it will present first clinical data from the ongoing Phase I/II study of ANV419, a powerful and selective interleukin-2 (IL-2) agonist in patients with solid tumors, in a poster presentation at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting in New Orleans, Louisana, April 8 to April 13, 2022 (Press release, Anaveon, MAR 9, 2022, View Source [SID1234609770]). Abstracts will be available online starting 1:00 pm ET on Friday, April 8, 2022.
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Details of the poster presentation are:
Abstract Title: "ANV419, an IL-2R-beta-gamma targeted antibody-IL-2 fusion protein, induces selective effector cell proliferation in patients with progressed cancer"
Presentation Number: CT140
Location: New Orleans Convention Center, Exhibit Halls D-H, Poster Section 35
Poster Board Number: 7
Authors: Elena Garralda, Guzman Alonso, Juanita Lopez, Heinz Läubli, Emiliano Calvo, Christoph Huber, Nicole Egli, Aswathy Nair, Kirsten Richter, Sangeetha Jetwa, Silvio Costanzo, Christoph Bucher
Date/Time: April 11, 2022 at 1:30 pm – 5:00 pm ET
Anaveon is undertaking a Phase I/II study to evaluate the safety, dosing and clinical activity of its lead program, ANV419, a powerful and selective interleukin-2 (IL-2) agonist in patients with solid tumors. The Company is pursuing multiple parallel Phase II programs in order to explore the full therapeutic potential of ANV419. In addition, Anaveon continues its work in developing follow-on compounds to expand on the success of ANV419 by delivering the IL-2 agonist to tumor fighting cells and thus expand the therapeutic potential into less immunogenic tumors. Alongside this, the Company is building on its cytokine engineering expertise with preclinical-stage programs harnessing the power of cytokines for therapeutic purposes.