On October 14, 2019 Dr. Reddy’s Laboratories Ltd. (BSE: 500124, NSE: DRREDDY, NYSE: RDY) reported that it will announce results for the second quarter ended September 30, 2019 on Friday, November 1, 2019 after the Board Meeting.

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Earnings Call

Following the release, the management of the Company will host an earnings call to discuss the Company’s financial performance. (Dial In and other details given below)

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The play back will be available after the earnings call, till November 8th, 2019. For play back dial in phone No: 022 7194 5757 / 022 6663 5757, and Playback Code is 31923.

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On October 14, 2019 Novigenix SA, a leading Immuno-Transcriptomics company that develops and commercializes solutions for early cancer detection and precision medicine, reported a collaboration agreement with RadioMedix Inc., a radiopharmaceutical company, to develop a precision diagnostic test based on Novigenix’s technology (Press release, Novigenix, OCT 14, 2019, View Source [SID1234540992]). The test will measure the response in patients with neuroendocrine tumors (NET) treated with Alpha and Beta Peptide Receptor Radionuclide Therapy (PRRT).

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In order to effectively monitor the response following PRRT, Novigenix will develop an immune-transcriptomic based precision diagnostic test using its proprietary LITOseek platform to monitor the effectiveness of the treatment in NET patients.

"We are very pleased to collaborate with Novigenix on the development of a molecular signature for the response to therapy, and to detect progressive disease, earlier than any conventional modalities currently available to our NET patients," said Dr. Ebrahim S. Delpassand, CEO of RadioMedix "Precise measurement of the therapy response against NET is extremely important for the management of NET patients."

Neuroendocrine tumors (NET) begin in the cells that have traits of both hormone-producing endocrine cells and nerve cells of the body’s neuroendocrine system. They are found throughout the body’s organs and help control many of the body’s functions. All NETs are considered malignant tumors and most of them take years to develop, grow slow but can begin in any part of the body. On average 6.6 individuals per 100,000 people are diagnosed with NET per year. In the US, approximately 12,000 individuals per year are diagnosed with NET and 170,000 are living with the disease. The diagnosis is mainly based on imaging technologies and endoscopy.

"Our goal is to have a precise molecular and highly sensitive and specific diagnostic test to manage patients with NET across the entire course of treatment and follow up," stated Dr. Jan Groen CEO of Novigenix. "This collaboration with RadioMedix highlights the potential of our immune-transcriptomic approach to potential pharma partners seeking liquid biopsy based precision diagnostic tests."

On October 14, 2019 PharmaCyte Biotech, Inc. (OTCQB: PMCB), a biotechnology company focused on developing cellular therapies for cancer and diabetes using its signature live-cell encapsulation technology, Cell-in-a-Box, reported that its partner, Austrianova Singapore (Austrianova), has completed the first of two staggered and back to back manufacturing runs for the production of PharmaCyte’s clinical trial product (Press release, PharmaCyte Biotech, OCT 14, 2019, View Source [SID1234540991]).

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The first manufacturing run has been completed successfully. A representative sample of frozen syringes filled with the encapsulated cells inside are in the process of being shipped to external testing laboratories for the release testing of the clinical trial product that is required by the U.S. Food and Drug Administration (FDA). The clinical trial product will be used in PharmaCyte’s clinical trial in locally advanced, inoperable pancreatic cancer (LAPC).

Also, about two weeks ago, the second of the two manufacturing runs began. The cells from PharmaCyte’s Master Cell Bank (MCB) are reportedly growing well. The plan is to encapsulate them within the next week or two.

PharmaCyte’s Chief Executive Officer, Kenneth L. Waggoner, commented, "We are exceedingly pleased that Austrianova has successfully manufactured PharmaCyte’s clinical trial product for our clinical trial in LAPC, and we’re equally as encouraged to hear that the second and final manufacturing run is proceeding as expected. During our recent shareholder update call, we committed to keeping our shareholders apprised of material developments related to PharmaCyte’s work in completing its Investigational New Drug application (IND). Today’s announcement is a major milestone towards the completion of that work.

"The efforts undertaken to meet this milestone were monumental and involved everyone associated with the technical aspects of the manufacturing process. We cannot be more thankful to our colleagues at Austrianova and those from PharmaCyte who were involved in the work. I feel strongly that we’re back on track to completing both of the required manufacturing runs that will generate the data needed to complete the IND."

During PharmaCyte’s shareholder update call on September 20, 2019, it was reported that Austrianova was in the post-encapsulation phase of the first of two staggered and back-to-back manufacturing runs required by cGMP Validation, the company that is taking responsibility for releasing the clinical trial product into the U.S. for use in PharmaCyte’s upcoming clinical trial.

To learn more about PharmaCyte’s pancreatic cancer treatment and how it works inside the body to treat locally advanced inoperable pancreatic cancer, we encourage you to watch the company’s documentary video complete with medical animations at: View Source

On October 14, 2019 Aptose Biosciences presented the corporate presentation (Presentation, Aptose Biosciences, OCT 14, 2019, View Source [SID1234540990]).

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On October 14, 2019 Onxeo S.A. (Euronext Paris, NASDAQ Copenhagen: ONXEO), ("Onxeo" or "the Company"), a clinical-stage biotechnology company specializing in the development of innovative drugs targeting tumor DNA Damage Response (DDR) in oncology, in particular against rare or resistant cancers, reported having received a communication from the European Patent Office (EPO) informing the Company of its intent to grant a new patent strengthening the European protection of compounds sourced from its platON platform (Press release, Onxeo, OCT 14, 2019, View Source [SID1234540989]).

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This new patent strengthens the patent portfolio around AsiDNA, the Company’s first-in-class DNA Damage Response (DDR) inhibitor. It protects AsiDNA and related compounds, as such and for their therapeutic use, in particular for the treatment of cancers, alone or in combination with other agents such as radiotherapy, chemotherapy or other tumor DNA-damaging agents.

"This intent-to-grant, which was obtained very quickly after filing the application, illustrates the value of our platON platform through its ability to generate new patentable compounds and confirms the highly innovative nature of the products resulting from our technology to block the signaling pathways involved in the repair of tumor DNA," said Françoise Bono, Chief Scientific Officer of Onxeo.

This patent will provide a term of protection valid until mid-2031, which could be further extended until 2036 via the supplementary protection certificate (SPC) system. It completes the already robust set of 9 patent families securing the protection of AsiDNA and its related compounds.