On September 19, 2019 Anixa Biosciences, Inc. (NASDAQ: ANIX), a biotechnology company focused on harnessing the body’s immune system to fight cancer, reported that Potomac Urology Center, PC ("PUC") has joined its Cchek early cancer detection study (Press release, Anixa Biosciences, SEP 19, 2019, View Source [SID1234539639]). PUC will provide patient samples for Anixa’s ongoing prostate cancer study, including support of clinical validation of Anixa’s Cchek Prostate Cancer Confirmation test.

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Dr. Nilay M. Gandhi, who will serve as the Principal Investigator at PUC for the study, stated, "We’re excited to take part in the development of Anixa’s Cchek prostate cancer detection test and we look forward to the impact this test may have on improving patient care."

"We are pleased to have PUC join us as a key collaborator in the development of Cchek, our artificial intelligence driven liquid biopsy for early cancer detection," stated Dr. Amit Kumar, CEO of Anixa. "Further, we look forward to PUC’s participation as we prepare for the commercial launch of our Cchek Prostate Cancer Confirmation test later this year."

PUC is an expert urology practice committed to providing the highest quality care to patients throughout the Northern Virginia area in the diagnosis and treatment of urology related conditions.

On September 18, 2019 Trobix Bio, a newly established start-up with a unique set of proprietary phage-based antibiotic resistance sensitizing solutions, reported that the Israel Innovation Authority (IIA) recently approved a grant for Trobix Bio to receive funding through the IIA "Early Stage Companies Incentive Program" (Press release, Trobix Bio, SEP 18, 2019, View Source [SID1234644363]). This funding will support the continuing development of novel products that abolish bacterial antibiotic resistance.

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The IIA, previously known as the Office of the Chief Scientist of Israel’s Ministry of Economy, is an independent publicly funded agency, which acts as the support arm of the Israeli government to help facilitate the development of industrial R&D within the State of Israel.

"Trobix Bio is pioneering the development of products to treat the global crisis of antimicrobial resistance, and the support of our program by the IIA is proof of their confidence in the potential of Trobix Bio to combat antibiotic resistance with our unique technology," said Dr. Adi Elkeles, Founder and CEO of Trobix Bio. "We are grateful for the financial support from the IIA, which complements our seed funding that was completed in March 2019, thus enabling us to spring board the development of our initial product pipeline."

On September 18, 2019 STORM Therapeutics, the biotechnology company focused on the discovery of small molecule therapies modulating RNA epigenetics reported that Oliver Rausch, Chief Scientific Officer of STORM Therapeutics will present first of its kind data on targeting RNA modifying enzymes for cancer treatment at its inaugural "RNA Epigenetics in Human Disease Conference" taking place at St Catharine’s College, Cambridge, UK on 17-20 September 2019 (Press release, STORM Therapeutics, SEP 18, 2019, View Source [SID1234561039]). Attendees are from renowned academic research institutions and pharmaceutical and biotechnology companies worldwide.

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The presentation will take place at 12:00 BST today, Wednesday 18th September and is entitled "Targeting RNA modifying enzymes for the treatment of cancer".

Oliver Rausch will present research encapsulating STORM’s ground-breaking work on targeting RNA modifying enzymes for cancer treatment. He will describe how it employs leading analytical and drug discovery capabilities to establish a comprehensive pharmacological audit trail linking therapeutic efficacy to METTL3 target and pathway inhibition. STORM has identified small molecule inhibitors of METTL3 that are orally bioavailable and show pronounced anti-tumour efficacy in physiologically relevant, proof of concept animal models of Acute Myeloid Leukaemia (AML). The talk will demonstrate that small molecule inhibition of METTL3 produces the same phenotype and effects previously described in one of STORM’s founder scientists publications using genetic models and validates METTL3 as a druggable target for cancer.

Keith Blundy, CEO of STORM Therapeutics, said: "STORM is the first Company in the world to demonstrate in vivo activity of an RNA methyltransferase inhibitor, showing proof of concept efficacy in animal models and is on course to enter the clinic in 2021. STORM is exploring the potential of its first-in-class inhibitors in various solid and haematological cancers and other therapeutic areas. We are excited to be leading the field as we look to develop these highly innovative new treatment options for cancer patients."

Tony Kouzarides, Founder of STORM Therapeutics, added: "We founded STORM Therapeutics to lead and accelerate development of drugs targeting RNA epigenetics. We are proud to be the first company making significant progress towards this aim, with multiple programmes in in vivo testing currently."

For more information on the RNA Epigenetics in Human Disease Conference and the programme please visit: https://stormtxconference2019.com/

On September 18, 2019 Fate Therapeutics, Inc. (the "Company" or "Fate Therapeutics") (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to the development of programmed cellular immunotherapies for cancer and immune disorders, reported the closing of an underwritten public offering of 9,890,000 shares of its common stock, which included 1,290,000 shares that were issued pursuant to the full exercise of the underwriters’ option to purchase additional shares, at a public offering price of $17.50 per share (Press release, Fate Therapeutics, SEP 18, 2019, View Source [SID1234539634]). Aggregate gross proceeds from this offering, including exercise of the option, were approximately $173.1 million, prior to deducting underwriting discounts and commissions and estimated offering expenses. Fate Therapeutics intends to use the net proceeds from the offering to fund clinical trials and nonclinical studies, the manufacture of its clinical product candidates, the expansion of its cGMP compliant manufacturing operations, the conduct of preclinical research and development, and for general corporate purposes.

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Jefferies, Citigroup, SVB Leerink and Wells Fargo Securities acted as joint book-running managers for the offering. Wedbush PacGrow and Cantor Fitzgerald & Co. acted as co-managers for the offering.

The securities described above were offered by Fate Therapeutics pursuant to a shelf registration statement on Form S-3 (File No. 333-228513) previously filed with and declared effective by the Securities and Exchange Commission (the "SEC"). A final prospectus supplement related to the offering was filed with the SEC on September 13, 2019 and is available on the SEC’s website at View Source Copies of the final prospectus supplement and the accompanying prospectus relating to the securities offered may also be obtained by contacting Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by e-mail at [email protected] or by telephone at (877) 821-7388; Citigroup Global Markets Inc., c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, or by telephone at (800) 831-9146; SVB Leerink LLC, Attention: Syndicate Department, One Federal Street, 37th Floor, Boston, MA 02110, by telephone at (800) 808-7525 ext. 6132 or by email at [email protected]; or Wells Fargo Securities, LLC, Attention: Equity Syndicate Department, 375 Park Avenue, New York, New York 10152, by email at [email protected] or by telephone at (800) 326-5897.

This press release does not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

On September 18, 2019 PTC Therapeutics, Inc. (Nasdaq: PTCT) reported the pricing of a public offering of 2,475,248 shares of its common stock at a public offering price of $40.40 per share, before underwriting discounts and commissions (Press release, PTC Therapeutics, SEP 18, 2019, View Source [SID1234539633]). In addition, PTC has granted the underwriter an option for a period of 30 days to purchase up to an additional 371,287 shares of common stock at the public offering price, less the underwriting discount.

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Credit Suisse is acting as the sole bookrunning manager for the public offering of common stock.

PTC expects to close the offering on or about September 20, 2019, subject to satisfaction of customary closing conditions. The offering of the common stock by PTC is not contingent upon the consummation of the previously announced concurrent private offering of the convertible senior notes (the "Notes"), and the concurrent private offering of the Notes is not contingent upon the consummation of the offering of common stock by PTC.

An automatically effective shelf registration statement on Form S-3 (File No. 333-220151) relating to the shares of common stock offered in the public offering has been filed with the Securities and Exchange Commission (the "SEC") and is available on the SEC’s website at www.sec.gov. A final prospectus supplement relating to and describing the terms of the offering also will be filed with the SEC and will be available on the SEC’s website at www.sec.gov. Before investing in the offering, interested parties should read the prospectus supplement and the accompanying prospectus for the offering and the other documents PTC has filed with the SEC that are incorporated by reference in the prospectus supplement and the accompanying prospectus, which provide more complete information about PTC and the offering. Copies of the prospectus supplement and the accompanying prospectus relating to the offering may be obtained from: Credit Suisse Securities (USA) LLC, Attention: Prospectus Department, Eleven Madison Avenue, 3rd floor, New York, NY 10010, or by telephone: (800) 221-1037, or by emailing [email protected].

This press release does not constitute an offer to sell, or a solicitation of an offer to buy, nor shall there be any sale of, these securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to the registration or qualification under the securities laws of such state or jurisdiction.