On December 5, 2017 BioLineRx Ltd. (NASDAQ/TASE:BLRX), a clinical-stage biopharmaceutical company focused on oncology and immunology, reported that on this date it hosts its investor breakfast meeting at the Convene Conference Center near Grand Central in New York, NY (Press release, BioLineRx, DEC 5, 2017, View Source;p=RssLanding&cat=news&id=2321125 [SID1234522378]).

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Philip Serlin, Chief Executive Officer of BioLineRx, stated, "This annual event gives us the opportunity to directly meet with our investors for updates on our progress: steady advancements on our multiple clinical programs in stem cell mobilization, combination immunotherapies and acute myeloid leukemia (AML), as well as our new and novel immuno-oncology therapy. And we are pleased to feature a presentation by Dr. John DiPersio, Chief, Division of Oncology at Washington University School of Medicine, an internationally-renowned hematologist and expert on the role of CXCR4 in stem-cell mobilization and hematological malignancies. There remains a large, unmet need for cancer therapies and we remain focused on advancing programs that improve upon current treatments and the standard of care."

In addition to the keynote presentation by Dr. DiPersio on bone marrow transplantation and the role of CXCR4 in cancer, additional topics for discussion at the ongoing BioLineRx investor breakfast meeting include: (i) presentation on BL-8040 clinical development plans in immuno-oncology combinations and AML, as well as on the upcoming GENESIS Phase 3 study in stem cell mobilization for autologous bone-marrow transplantation in multiple myeloma patients; (ii) presentation of AGI-134, the Company’s novel immuno-oncology project; and (iii) an overview of the Company’s plans and expected milestones for 2018.

BioLineRx is hosting a live webcast of the investor breakfast today between 9:00-10:30 am ET. To access the webcast, please go to the breakfast event page on BioLineRx’s website. An audio replay of the meeting will also be available for approximately three months following the meeting on the breakfast event page.

On December 5, 2017 BioLineRx presented Corporate Presentation (Presentation, BioLineRx, DEC 5, 2017, View Source [SID1234522388]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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On December 5, 2017 Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in T-cell therapy to treat cancer, reported that it will update data from its completed pilot study1 of NY‑ESO SPEAR T-cell therapy in multiple myeloma patients in the setting of autologous stem cell transplant (ASCT) presented at the annual ASH (Free ASH Whitepaper) meeting at the Georgia World Congress Center in Atlanta, Ga (Press release, Adaptimmune, DEC 5, 2017, View Source;p=RssLanding&cat=news&id=2321280 [SID1234522387]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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During an oral presentation, Dr. Edward Stadtmauer, University of Pennsylvania Abramson Cancer Center, will present an update on all twenty-five multiple myeloma patients treated in Adaptimmune’s pilot study in the setting of ASCT. The data cut-off for the abstract was through July 2017, the data cut-off for the oral presentation was August 16, 2017.

Oral Presentation 845: Phase I/IIa Study of Genetically Engineered NY-ESO-1 SPEAR T-Cells Administered Following Autologous Stem Cell Transplant in HLA-a*02+ Patients with Advanced Multiple Myeloma: Long Term Follow‑up (NCT01352286)

Session: 703. Adoptive Immunotherapy: Gene Engineered T cells for Hematologic Malignancies

Time: Monday, December 11, 2017: 5:30 PM (EST)

Location: Bldg. B, Level 2, B206 (Georgia World Congress Center)

Result highlights from the abstract include:

Overall response rate (ORR) at day 100 was 76% (1 stringent complete response [sCR]; 12 very good partial response [VGPR]; 6 partial response [PR])
At year 1, 13 patients were progression free (52%) of which 11 were responders (1 sCR; 1 CR; 8 VGPR; 1 PR)
Three patients remain disease progression-free at 39, 56, and 61 months post T-cell infusion
Median progression free survival (PFS) was ~13 months (range 3-61 months)
Eleven of 25 patients (44%) are alive, and median survival was ~35 months (range 6-68 months)
Autologous GvHD (24%) was reported in 6 patients (3 G3, 3 ≤G2); all resolved with corticosteroids and supportive therapy
No fatal adverse events have been reported

On December 5, 2017 MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) reported that it will host an Investor & Analyst conference call and webcast on its investigational proprietary program MOR208 on December 12, 2017 at 5:00 pm CET (4:00 pm GMT, 11:00 am EST) after the 2017 ASH (Free ASH Whitepaper) Annual Meeting (Press release, MorphoSys, DEC 5, 2017, View Source [SID1234522383]).

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In the call the MorphoSys Management will present and discuss updated clinical data from the ongoing phase 2 L-MIND trial with the Company’s investigational program MOR208 in combination with lenalidomide in patients with relapsed or refractory diffuse large B cell lymphoma (R/R DLBCL), which had been presented in a poster at the 2017 ASH (Free ASH Whitepaper) Annual Meeting in Atlanta on December 11th.

Dial-in numbers (listen only):

Germany: +49 89 2444 32975
United Kingdom: +44 20 3003 2666
USA: +1 202 204 1514

Participants are kindly requested to dial in up to 10 minutes before the call to ensure a prompt start and a secure line.

The presentation slides and webcast link will be available at the Company’s website at www.morphosys.com/conference-calls

A slide-synchronized audio replay of the conference will also be available at the corporate website following the live event.

On December 5, 2017 Moleculin Biotech, Inc. presented Investor Presentation (Presentation, Moleculin, DEC 5, 2017, View Source [SID1234522381]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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