(Press release, Selvita, APR 15, 2013, View Source [SID:1234505616])

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!


MOLOGEN AG: Skin cancer study with MGN1404 approved

MOLOGEN AG: Skin cancer study with MGN1404 approved

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Evaluation of safety and tolerability
Further product candidate ready for phase I clinical study
Study under the direction of the Charité Universitätsmedizin

The Paul-Ehrlich Institute has granted approval for a phase I clinical study of a gene therapy with MGN1404 for the treatment of melanomas (Press release Mologen, APR 15, 2013, View Source [SID:1234501173]). The study is entitled "Phase I trial of TNF-alpha expressing MIDGE-vector non-viral gene transfer in skin metastases of melanoma." The study will be conducted by collaborative partners Charité Comprehensive Cancer Center (CCCC), the Berlin Experimental and Clinical Research Center of the Charité (ECRC), the Max Delbrück Center for Molecular Medicine (MDC) in Berlin-Buch and the skin cancer center of the Charité (Hauttumorcentrum, HTCC).

The study will examine whether the MIDGE vector is safe and well tolerated when applied by intra-tumor jet injector, and whether the application leads to efficient expression of the hTNF-alpha gene. Further, the magnitude and extent of gene expression and the distribution of the MIDGE vector within and outside the injected tumor will be examined. Three different doses of the MIDGE vector will be used. This study is a first step towards the clinical use of local gene therapy for malignant melanomas.

ACADEMIA-INDUSTRY PARTNERSHIP CREATES BLUEPRINT FOR COLLABORATION TO DEVELOP INNOVATIVE NEW CANCER TREATMENT

On April 11, 2013 Pharmascience Inc. and Université de Montréal reported the signing of an agreement which formalizes and brings to the next level of activity a collaboration that demonstrates the value of academic research, public institutions, patient disease groups and the pharmaceutical industry working together to bring new hope to patients (Press release, Université de Montréal, APR 11, 2013, View Source [SID1234626501]). The agreement was coordinated by the university’s Institute for Research in Immunology and Cancer – Commercialization of Research (IRICoR).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The result could be a new use for an old drug, and new hope for people with certain types of acute myeloid leukemia (AML), a blood cancer which today has very few treatment options and only a 10 per cent five-year survival rate. It is a story that demonstrates very clearly the benefits a multi-faceted biopharmaceutical cluster such as the one which exists in Greater Montreal can bring together to make a very complex undertaking possible.

It starts with Dr. Katherine Borden, a Montreal-born research scientist who, after 20 years of education and research in the United States and United Kingdom, was enticed by the Montreal research environment to return in 2004 as the Canada Research Chair in the Molecular Biology of the Cell Nucleus. She is a Professor in the Department of Pathology and Cell Biology in the Faculty of Medicine at Université de Montréal, as well as a Principal Investigator for the university’s Institute for Research in Immunology and Cancer (IRIC).

(Press release, Syros Pharmaceuticals, APR 11, 2013, View Source [SID:1234506060])

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!


(Filing 10-K , Cellular Biomedicine Group, APR 4, 2013, View Source [SID:1234501604])

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!