Ipsen delivers robust sales growth in the first quarter of 2023 and confirms its full-year guidance

On April 27, 2023 Ipsen, a global specialty-driven biopharmaceutical company, reported its sales performance for the first quarter of 2023 (Press release, Ipsen, APR 27, 2023, View Source [SID1234630958]).

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10-Q – Quarterly report [Sections 13 or 15(d)]

Eli Lilly has filed a 10-Q – Quarterly report [Sections 13 or 15(d)] with the U.S. Securities and Exchange Commission .

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Immutep Quarterly Activities Report & Appendix 4C Q3 FY23

On 27 April 2023 Immutep Limited "Immutep" or "the Company", a biotechnology company developing novel LAG-3 related immunotherapy treatments for cancer and autoimmune diseases, provides an update on the ongoing development of its product candidates, eftilagimod alpha (efti) and IMP761 for the quarter ended 31 March 2023 (Q3 FY23) (Press release, Immutep, APR 27, 2023, View Source [SID1234630689]).

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TME Pharma Announces New Data From NOX-A12 GLORIA Phase 1/2 Study in Glioblastoma to Be Presented at ASCO Annual Meeting in June 2023

On April 27, 2023 TME Pharma N.V. (Euronext Growth Paris: ALTME), a biotechnology company focused on developing novel therapies for treatment of cancer by targeting the tumor microenvironment (TME), reported that new data from the GLORIA Phase 1/2 clinical trial evaluating NOX-A12 in brain cancer (glioblastoma) will be presented in a poster presentation at the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) Annual Meeting taking place in Chicago from June 2-6, 2023 (Press release, TME Pharma, APR 27, 2023, View Source [SID1234630648]).

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"We are very pleased that the ASCO (Free ASCO Whitepaper) Scientific Program Committee has chosen the GLORIA trial for presentation at this year’s ASCO (Free ASCO Whitepaper) Annual Meeting, which is one of the highest-profile and most selective conferences where researchers from around the world come to learn about clinical trials of promising new cancer therapies. We look forward to sharing these groundbreaking new data and analysis coming from the GLORIA study at the ASCO (Free ASCO Whitepaper) conference," said Aram Mangasarian, CEO of TME Pharma.

Details of Presentation:
Title: Potential predictive biomarker for response to radiotherapy and CXCL12-inhibition in glioblastoma in the phase 1/2 GLORIA trial (abstract #2048)
Presenter: Dr. Frank A. Giordano, Professor and Chair of the Department of Radiation Oncology at the University Medical Center Mannheim, Germany, and the lead investigator of the GLORIA trial.
Session Type: Poster Session
Session Title: Central Nervous System Tumors
Session Date and Time: June 3, 2023, 01:15-04:15pm CST
Registration: To register to the event, please click here

The full abstract will be published online by ASCO (Free ASCO Whitepaper) on May 25, 2023, at 05.00 p.m. EDT (11.00 p.m. CEST). TME Pharma will share the details of the presentation as they become publicly available by the annual meeting organizer.

ASCO is the world’s leading professional organization for physicians and oncology professionals caring for people with cancer. Its flagship event, the Annual Meeting, promotes cutting-edge research and attracts more than 40,000 oncology professionals from around the world every year.

First Patient Dosed in the US in Avacta’s AVA6000 Phase 1 Clinical Study

On April 27, 2023 Avacta Group plc (AIM: AVCT), a life sciences company developing innovative, targeted oncology drugs and powerful diagnostics, reported that the first patient has been dosed in the US under its Investigational New Drug (IND) Application in Avacta’s phase 1 multi-centre trial evaluating the safety and tolerability of AVA6000, a novel tumour targeted form of doxorubicin and Avacta’s first therapeutic product based on its proprietary pre|CISION technology (Press release, Avacta, APR 27, 2023, View Source [SID1234630647]).

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The first patient in the US has been dosed in the dose-escalation study in patients with locally advanced or metastatic selected solid tumours, known to be FAP-positive, at the Memorial Sloan Kettering Cancer Center in New York.

For more information visit www.clinicaltrials.gov (NCT04969835).

Dr Alastair Smith, Chief Executive Officer, Avacta Group plc, commented: "The US trial sites in New York and Seattle will play a key role, along with other sites in the UK and US, in this multi-centre trial both in the dose escalation phase and in the dose expansion phase which we expect to begin in the second half of the year."

"Dosing the first patient in the US is a key milestone and reflects the continuing excellent progress in the ALS-6000-101 clinical trial and the Therapeutics Division as a whole."