Champions Oncology Reports Quarterly Revenue of $12.9 Million

On July 21, 2022 Champions Oncology, Inc. (Nasdaq: CSBR), a leading global technology-enabled biotech that is transforming drug discovery through innovative AI-driven pharmaco-pheno-multiomic integration, reported its financial results for the year and fourth fiscal quarter ended April 30, 2022 (Press release, Champions Oncology, JUL 21, 2022, View Source [SID1234616869]).

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Fourth Quarter and Fiscal Year 2022 Financial and Recent Business Highlights:
•Fourth quarter revenue increased 22% to $12.9 million
•Record annual revenue of $49.1 million, an increase of 20% year-over-year
•Achieved high end of revenue guidance of 20%
•Gross margin improved to 52% for fiscal year 2022
•Adjusted EBITDA of $3.1 million for fiscal year 2022

Ronnie Morris, CEO of Champions, commented, "Fiscal year 2022 was an outstanding year for Champions as we successfully expanded our business lines while continuing to develop and implement our longer term strategies. Our ex-vivo business was especially promising as we saw rising demand for those services. Our computational discovery tools continue to evolve and this upcoming year will focus on moving these programs into preclinical development."

David Miller, CFO of Champions added, "We realized another year of financial milestones, reaching a record $49.1 million in revenue and delivering 20% top line growth, in line with the high end of revenue guidance. Our pipeline of opportunities remains robust and with the expansion of our platforms, we are well positioned to deliver strong financial results in fiscal year 2023. We’re projecting another year of top line revenue growth in the 20% range."

Fourth Fiscal Quarter Financial Results

Total revenue for the fourth quarter of fiscal 2022 was $12.9 million, an increase of 22%, compared to $10.6 million for the same period last year. The increase in revenue was due to continued demand and larger study sizes for our pharmacology studies, including in-vivo and ex-vivo services. Total costs and operating expenses for the fourth quarter of fiscal 2022 were $13.2 million compared to $11.0 million for the fourth quarter of fiscal 2021, an increase of $2.2 million or 20%.

For the fourth quarter of fiscal 2022, Champions reported a loss from operations of $311,000, which includes $188,000 in stock-based compensation and $568,000 in depreciation and amortization compared to a loss from operations of $456,000, inclusive of $161,000 in stock-based compensation and $302,000 in depreciation and amortization in the fourth quarter of fiscal 2021. Excluding stock-based compensation, depreciation and amortization expenses, Champions

reported adjusted EBITDA for the quarter of $445,000, compared to $7,000 in the prior year period.

Cost of oncology solutions was $6.2 million for the three months ended April 30, 2022, an increase of $568,000, or 10% compared to $5.7 million for the three months ended April 30, 2021. The increase in cost of sales was primarily due to an increase in compensation expense for our SaaS platform. For the three months ended April 30, 2022, gross margin was 52% compared to 46% for the three months ended April 30, 2021. The improvement in gross margin was the direct result of decreasing the Company’s reliance on outsourcing and leveraging revenue growth over the fixed cost component of cost of sales.
Research and development expense was $2.6 million for the three months ended April 30, 2022, an increase of $520,000, or 25%, compared to $2.1 million in the prior year. The increase was primarily due to compensation and lab expenses as we increased investment in our drug discovery program. Sales and marketing expense for the three months ended April 30, 2022 was $1.6 million, remaining relatively flat with an increase of $143,000, or 10%, compared to $1.5 million for the three months ended April 30, 2021. General and administrative expense was $2.8 million for the three months ended April 30, 2022 compared to $1.8 million for the three months ended April 30, 2021, an increase of $936,000, or 51%. The increase was primarily due to an increase in depreciation and amortization expenses of approximately $300,000, write-off of bad debt of $200,000, and an increase in IT expenses, specific to computing costs, of $300,000 to support the overall growth of the organization.

Net cash generated from operating activities for the quarter was approximately $700,000 resulting from operating income excluding stock-based compensation and other non-cash related expenses, and an increase in deferred revenue stemming from our bookings growth. Net cash used in investing activities was $400,000 primarily from investment in additional lab equipment. The Company ended the quarter with a strong cash position of $9.0 million and no debt.

Year-to-Date Financial Results

Total revenue for fiscal year 2022 was $49.1 million, an increase of 20%, compared to $41.0 million for fiscal year 2021. The increase in revenue was due to the expansion of our platforms, business lines, and demand for our services. Total operating expenses increased 19% to $48.5 million for fiscal year 2022, as compared to $40.7 million for the prior year.

For the twelve months ended April 30, 2022, Champions reported net income from operations of $607,000, inclusive of $912,000 in stock-based compensation expense and $1.6 million in depreciation and amortization expenses compared to income from operations of $366,000, inclusive of $598,000 in stock-based compensation expense, and $1.2 million in depreciation and amortization expenses for the prior year. Excluding stock-based compensation, depreciation and amortization, Champions reported adjusted EBITDA of $3.1 million for fiscal year 2022 compared to adjusted EBITDA of $2.1 million in the prior year.

Cost of oncology solutions was $23.6 million for the twelve months ended April 30, 2022, an increase of $2.2 million or 10%, compared to $21.4 million, for the twelve months ended April 30, 2021. The increase in cost of oncology services was mainly due to an increase in compensation and supply expenses resulting from increased study volume and compensation expenses for our SaaS platform. These increases were offset by a decrease in outsourced lab services. Gross margin was 52% for the twelve months ended April 30, 2022 compared to 48% for the twelve months ended April 30, 2021.The improvement in gross margin was the direct result of decreasing the Company’s reliance on outsourcing and leveraging revenue growth over the fixed cost component of cost of sales.

Research and development expense was $9.4 million for fiscal year 2022, an increase of $2.2 million, or 30%, compared to $7.2 million for the prior year. The increase was mainly due to the investment in therapeutic discovery programs with the increase coming primarily from compensation and lab supply expenses. Sales and marketing expense for fiscal year 2022 was $6.4 million, an increase of $859,000, or 16%, compared to $5.5 million for fiscal year 2021. The increase was primarily due to compensation expense driven by the continued expansion of our business development teams and travel expenses which increased with the easing of Covid restrictions. General and administrative expense was $9.1 million for fiscal year 2022, an increase of $2.6 million, or 40%, compared to $6.5 million for fiscal year 2021. General and administrative expenses were primarily comprised of compensation, insurance, professional fees, IT, and depreciation and amortization expenses. The increase in general and administrative expense was primarily due to increases in non-cash expenses of $900,000, compensation, and IT computing expenses to support the overall growth of the company.

Net cash generated from operations was $6.5 million for fiscal year 2022. Cash generated from operations was primarily due to improving cash based operational results as well as an increase in deferred revenue due to strong bookings. Changes in working capital accounts occurred in the ordinary course of business. Net cash used in investing activities was $2.4 million primarily from investment in additional lab equipment and software development costs. The Company ended the year in strong cash position of $9.0 million and has no debt.

Conference Call Information:

The Company will host a conference call today at 4:30 p.m. EDT (1:30 p.m. PDT) to discuss its fourth quarter financial results. To participate in the call, please call 888-506-0062 (domestic) or 973-528-0011 (international) ten minutes ahead of the call and enter the access code 908668. A replay of the call will be available by dialing 877-481-4010 (Domestic) or 919-882-2331 (International) and entering passcode: 46134, or by accessing the investors section of the company’s website within 72 hours.

Full details of the Company’s financial results will be available on, or before, Monday July 25, 2022 in the Company’s Form 10-K at View Source

* Non-GAAP Financial Information

See the attached Reconciliation of GAAP to non-GAAP Net Income (loss) (Unaudited) for an explanation of the amounts excluded to arrive at non-GAAP net income (loss) and related non-GAAP net income per share amounts for the three and twelve months ended April 30, 2022 and 2021. Non-GAAP financial measures provide investors and management with supplemental measures of operating performance and trends that facilitate comparisons between periods before and after certain items that would not otherwise be apparent on a GAAP basis. Certain unusual or non-recurring items that management does not believe affect the Company’s basic operations do not meet the GAAP definition of unusual or non-recurring items. Non-GAAP net income (loss) and non-GAAP income (loss) per share are not, and should not be viewed as a substitute for similar GAAP items. Champions’ defines non-GAAP dilutive income (loss) per share amounts as non-GAAP net income (loss) divided by the weighted average number of diluted shares outstanding. Champions’ definition of non-GAAP net income (loss) and non-GAAP diluted income (loss) per share may differ from similarly named measures used by others.

Vivesto appoints Christer Nordstedt as acting CEO

On July 21, 2022 Vivesto AB ("Vivesto" or the "Company"), an oncology-focused specialty pharmaceutical company, hereby reported that the Board of Directors of the Company today has appointed Christer Nordstedt as acting CEO of the Company (Press release, Vivesto, JUL 21, 2022, View Source [SID1234616868]).

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Christer assumes the position as acting CEO on 21 July 2022 and will hold the position until the recruitment of a permanent CEO is completed.

Peter Zonabend, Chairman of the Board of Vivesto, says: "We are very pleased to appoint Christer Nordstedt as acting CEO. Christer has a proven track record within R&D and his leadership ensures that we will achieve our goals. With his long and very relevant experience in R&D, Christer will be able to continue the strategic direction of Vivesto to become a strong oncology company through own development and future partnerships."

Christer Nordstedt is a Doctor of Medicine and has a PhD in Pharmacology and Biochemistry from the Karolinska Institute in Sweden and did his postdoctoral training with the Nobel laureate Paul Greengard at Rockefeller University in New York. Christer has many years of experience, including leading a large number of projects in the pharmaceutical industry from the earliest discovery all the way through clinical development, and has held positions such as Global Head of Specialty Research and Clinical Development and Senior Vice President Global Head of Clinical Development at Teva Pharmaceuticals, Head of R&D at Orion Cooperation as well as Senior Vice President at Hoffman-LaRoche in Basel and at Eli Lilly in Indianapolis. Currently, Christer is Chairman of the Board of WntResearch AB and engaged as a consultant at BioArctic AB. Christer does not own any shares or share-related instruments in Vivesto.

Compugen to Release Second Quarter Results on Thursday, August 4, 2022

On July 21, 2022 Compugen Ltd. (Nasdaq: CGEN), a clinical-stage cancer immunotherapy company and a pioneer in computational target discovery, reported that the Company will release its second quarter financial results on Thursday, August 4, 2022, before the U.S. financial markets open (Press release, Compugen, JUL 21, 2022, View Source [SID1234616865]). Management will host a conference call and webcast to review the results and provide a corporate update at 8:30 AM ET.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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To access the live conference call by telephone, please dial 1-866-744-5399 from the U.S., or +972-3-918-0644 internationally. The call will be available via live webcast through Compugen’s website, located at the following link.

Following the live webcast, a replay will be available on the Company’s website.

Insmed to Host Second Quarter 2022 Financial Results Conference Call on Thursday, August 4, 2022

On July 21, 2022 Insmed Incorporated (Nasdaq:INSM), a global biopharmaceutical company on a mission to transform the lives of patients with serious and rare diseases, reported that it will release its second quarter 2022 financial results on Thursday, August 4, 2022 (Press release, Insmed, JUL 21, 2022, View Source [SID1234616864]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Insmed management will host a conference call for investors beginning at 8:30 a.m. ET on Thursday, August 4, 2022 to discuss the financial results and provide a business update.

Shareholders and other interested parties may participate in the conference call by dialing (888) 210-2654 (U.S.) or (646) 960-0278 (international) and referencing access code 7862189. The call will also be webcast live on the company’s website at www.insmed.com.

A replay of the conference call will be accessible approximately 2 hours after its completion through September 3, 2022, by dialing (800) 770-2030 (U.S.) or (647) 362-9199 (international) and referencing access code 7862189. A webcast of the call will also be archived for 90 days under the Investor Relations section of the company’s website at www.insmed.com.

Imagia Canexia Health and Anwa Medical Company Enter Memorandum of Understanding to Bring Liquid Biopsy to Middle East and North Africa (MENA)

On July 21, 2022 -Imagia Canexia Health, a genomics-based cancer treatment testing company that accelerates access to precision care by combining AI expertise with advanced molecular biopsy solutions, and Anwa Medical Co ("Anwa"), a leading genomic diagnostics laboratory group in the Kingdom of Saudi Arabia ("Saudi Arabia"), reported that they have entered a Memorandum of Understanding (MOU) to take Imagia Canexia Health’s distributed liquid biopsy testing products into Saudi Arabia and the rest of the Middle East and North Africa ("MENA") region (Press release, Canexia Health, JUL 21, 2022, View Source [SID1234616863]). ICH offers liquid biopsy products for treatment selection and patient monitoring that can be run at or near the point of care for cancer patients rather than having to send samples to centralized laboratories located overseas. This allows cancer patients globally to access advanced precision oncology treatment with a shorter turnaround time and lower cost.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Imagia Canexia Health and Anwa will initially focus on offering the tests in Saudi Arabia before expanding throughout the MENA region. This will provide advanced cancer care to a population of over 500 million people who will see improved patient outcomes from wider access to advanced technologies for the diagnosis of cancer that also support the use of precision treatments. Providing treatment in the country will support the development of domestic precision oncology and genomics expertise and the infrastructure needed to support future treatments and development. Furthermore, for the first time, oncologists in the MENA region will be able to collect and analyse real world data from a wide group of patients from the MENA region, giving them more specific data and insights to support treatment decisions.

"Entry into this Memorandum of Understanding is a major step forward in improving cancer care in MENA and increasing health equity," said Imagia Canexia Health CEO Geralyn Ochab. "Imagia Canexia Health’s core mission has always been to help address inequalities in access to oncology care across the world. Taking our product to MENA is a major step forward to ensure that cancer patients in this large, growing part of the world can access cutting edge cancer care at home, rather than having to travel to receive care."

Dr. Saeed Al Turki, CEO of Anwa, said, "Saudi Arabia is one of the largest MENA markets, and its advanced healthcare sector constantly evolves with cutting-edge technologies. The partnership with Imagia Canexia Health expands Anwa services with new genomic assays to implement precision medicine practices in the MENA region. The A.I. platform enables us to link our population’s cancer biomarkers with prognostic insights and therapeutic options."

Ben Jelloun, Co-founder and Managing Partner of Global Connectivity Capital Investment (GCCVest), said, "We are delighted to have the opportunity to bring together Imagia Canexia Health and Anwa to form a strategic partnership to expand liquid biopsy testing products in the Kingdom. In addition, the partnership will leverage Imagia Canexia Health’s AI capabilities to empower healthcare providers in Saudi Arabia to compete with the premier Cancer Centers overseas by delivering locally an ‘in-house’ AI & precision oncology solutions saving time and cost. As an investment platform dedicated to bridging MENA to global investment opportunities, we believe technologies such as what Imagia Canexia Health offers, have great ‘localization’ potential that democratizes access to the latest global innovation."