Olema Oncology to Participate in Upcoming Investor Conferences

On May 9, 2025 Olema Pharmaceuticals, Inc. ("Olema", "Olema Oncology", Nasdaq: OLMA) a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted therapies for breast cancer and beyond, reported that the Company will participate in the following upcoming investor conferences (Press release, Olema Oncology, MAY 9, 2025, View Source [SID1234652824]):

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H.C. Wainwright 3rd Annual BioConnect Investor Conference
Date: Tuesday, May 20, 2025 at 4:30 p.m. ET
Format: Fireside Chat
Location: New York, NY

T.D. Cowen 6th Annual Oncology Innovation Summit: Insights for ASCO (Free ASCO Whitepaper) and EHA (Free EHA Whitepaper)
Date: Tuesday, May 27, 2025 at 5 p.m. ET
Format: Fireside Chat
Location: Virtual

Live webcasts and recordings of these presentations will be available, as permitted by the event host, in the Events and Presentations section of Olema’s investor relations website at ir.olema.com.

Lilly plans to expand Purdue University collaboration with up to a $250 million investment to accelerate pharmaceutical innovation

On May 9, 2025 Eli Lilly and Company (NYSE: LLY) and Purdue University reported a significant expansion of their long-standing alliance, with Lilly’s planned investment of up to $250 million in the collaboration over the next eight years (Press release, Eli Lilly, MAY 9, 2025, View Source [SID1234652822]). This partnership, which has the potential to be the largest ever industry-academic agreement of its kind in the United States, will seek to accelerate innovation at every stage of the pharmaceutical pipeline.

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The Lilly-Purdue 360 Initiative aims to achieve several key goals, including discovering and accelerating the delivery of medicines to patients; bridging the gap between laboratory discoveries and clinical applications; creating more resilient, efficient and sustainable supply chains; and deploying innovative, scalable approaches to workforce development. The expanded collaboration is also expected to generate significant economic benefits for Indiana by creating a highly skilled workforce and fostering local innovation.

The earlier agreement, which had been set to expire in 2027, will now extend with four new projects added through 2032. Additionally, it will engage existing joint programs, such as Lilly Scholars at Purdue and the Lilly and Purdue Research Alliance Center (LPRC). Purdue will make space available for Lilly researchers on-site in West Lafayette. Purdue researchers will collaborate in Lilly facilities in Indianapolis and in Indiana’s LEAP Research and Innovation District.

"As potentially the largest single university-industry research agreement in American history, Lilly and Purdue are blazing a new trail to the endless frontier," said Purdue University President Mung Chiang. "As for our state, when its largest company and the largest university expand collaboration at a scale never seen before, especially in the backdrop of Lilly’s manufacturing facility in LEAP, today marks a monumental watershed in the generation of jobs, workforce, and innovation along America’s Hard-Tech Corridor. We thank Lilly for its pioneering impact on health and medicine in our society and for what is now the largest single research funding, from public or private capital, in Purdue’s history."

To achieve the initiative’s ambitious goals, Lilly and Purdue will concentrate on several key areas:

Applying AI-powered tools to augment traditional drug discovery methods while leveraging advancements in machine learning and big data analytics to explore disease mechanisms and personalized treatments
Facilitating technology-enabled approaches to accelerate potential treatments from Phase I clinical studies to regulatory approval and technology transfer into manufacturing — critical focus areas of the Lilly Medicine Foundry
Incorporating robotics, AI, and data sciences to quickly scale manufacturing capacity more effectively, with improved compliance and greater sustainability
Enhancing workforce development to ensure a strong talent pipeline to meet the demands of Lilly and other Indiana employers
"Accelerating the delivery of life-changing medicines demands a highly skilled workforce and continuous innovation across discovery, process development and manufacturing," said David A. Ricks, Lilly’s chair and CEO. "Through this expanded collaboration with Purdue, we look forward to combining our strengths in advanced technologies and cutting-edge science to pioneer new methods of delivering next-generation medicines to advance human health."

The Lilly-Purdue 360 Initiative supports Purdue’s One Health initiative, which advances knowledge and innovation related to animal, human, and plant well-being through novel interdisciplinary initiatives and partnerships with industry.

Celularity Announces Full Year 2024 Operating and Financial Results

On May 9, 2025 Celularity Inc. (Nasdaq: CELU) ("Celularity" or the "Company"), a regenerative and cellular medicine company, reported operating and financial results for the year ended December 31, 2024 (Press release, Celularity, MAY 9, 2025, View Source [SID1234652821]).

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"We built momentum through 2024 and ended the year with a strong finish, as reflected in higher net revenues from the sale of our commercial-stage advanced biomaterial products," said Dr. Robert Hariri, M.D., Ph.D., CEO and Chairman. "Sales growth was notably strong for our Biovance product line, which we believe will continue to contribute to an improving revenue outlook for the next several quarters. We were also extremely pleased to receive recommendation letters from the U.S. Food and Drug Administration Tissue Reference Group regarding important additions to our portfolio of human placental-derived advanced biomaterial products, which serves as a testament to our commitment to innovate in the wound care sector along with our development of next-generation 510(k) products. At the same time, we continued to act opportunistically and explore opportunities in the rapidly evolving landscape of cellular and regenerative medicine. We believe Celularity will gain additional momentum in 2025 as we leverage our unique business model and world-class technical infrastructure and human capital."

Highlights of Full Year 2024 Operating and Financial Results

Net Revenues

Net revenues for the year ended December 31, 2024, was $54.2 million, an increase of $31.4 million, or 138.1%, compared to the prior year period. This growth was primarily due to a $22.2 million increase in product sales in wound care applications, which increased 168.7% over the prior year.

Operating Expenses

Total operating expenses for the year ended December 31, 2024, were $92.6 million, a decrease of $122.5 million, or 57.0%, compared to 2023. The decrease in operating expenses is attributable to the absence of goodwill and in-process research and development, or IPR&D, impairments in 2024. Loss from operations for the year ending December 31, 2024, was $38.4 million, a decrease of $153.9 million, or 80.1%, compared to the previous year, driven by higher revenue and lower operating expenses which improved our gross margin.

Results of Operations
Comparison of Year Ended December 31, 2024 to December 31, 2023

(in thousands) Year Ended December 31, Percent
2024 2023 Change Change
Revenues:
Product sales, net $ 35,336 $ 13,149 $ 22,187 168.7%
Services 5,140 5,441 (301) (5.5)%
License, royalty and other 13,744 4,181 9,563 228.7%
Total revenues 54,220 22,771 31,449 138.1%
Operating expenses:
Cost of revenues (excluding amortization of acquired
intangible assets)
Product sales 4,924 8,628 (3,704) (42.9)%
Services 1,172 1,650 (478) (29.0)%
License, royalty and other 8,893 5,738 3,155 55.0%
Research and development 17,386 30,465 (13,079) (42.9)%
Selling, general and administrative 58,643 50,576 8,067 16.0%
Change in fair value of contingent consideration liability (193) (104,339) 104,146 (99.8)%
Goodwill impairment — 112,347 (112,347) (100.0)%
IPR&D impairment — 107,800 (107,800) (100.0)%
Amortization of acquired intangible assets 1,753 2,193 (440) (20.1)%
Total operating expenses 92,578 215,058 (122,480) (57.0)%
Loss from operations $ (38,358) $ (192,287) $ 153,929 (80.1)%
CELULARITY INC.
CONSOLIDATED BALANCE SHEETS
(In thousands, except share and per share amounts)

December 31,
2024 2023
Assets
Current assets:
Cash and cash equivalents $ 738 $ 227
Accounts receivable, net of allowance of $6,294 and $5,837 as of December 31, 2024 and 2023, respectively 13,557 10,046
Notes receivable — 2,072
Inventory 5,409 5,753
Prepaid expenses and other current assets 857 1,695
Total current assets 20,561 19,793
Property and equipment, net 61,600 67,828
Goodwill 7,347 7,347
Intangible assets, net 9,248 11,001
Right-of-use assets – operating leases 10,830 10,990
Restricted cash 10,239 9,936
Inventory, net of current portion 12,587 16,657
Other long-term assets 270 337
Total assets $ 132,682 $ 143,889
Liabilities and Stockholders’ Equity
Current liabilities:
Accounts payable $ 23,296 $ 14,144
Accrued expenses and other current liabilities 19,842 7,580
Accrued R&D software — 3,500
Acquisition-related contingent consideration 650 —
Short-term debt – unaffiliated (includes debt measured at fair value of $2,485 and $17,223 as of December 31, 2024 and 2023, respectively) 2,485 19,331
Short-term debt – related parties 3,876 19,909
Deferred revenue 3,531 2,834
Total current liabilities 53,680 67,298
Deferred revenue, net of current portion 2,724 3,186
Acquisition-related contingent consideration, net of current portion 1,413 1,606
Long-term debt – related parties 35,927 —
Long-term lease liabilities 26,548 26,177
Warrant liabilities 3,264 4,359
Deferred income tax liabilities 9 9
Other liabilities 280 294
Total liabilities 123,845 102,929
Commitments and Contingencies (Note 12)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 10,000,000 shares authorized, none issued and outstanding as of December 31, 2024 and 2023 — —
Common stock, $0.0001 par value, 730,000,000 shares authorized, 22,546,671 and 19,378,192 issued and outstanding as of December 31, 2024 and 2023, respectively 2 19
Additional paid-in capital 908,523 882,732
Accumulated deficit (899,683) (841,791)
Accumulated other comprehensive loss (5) —
Total stockholders’ equity 8,837 40,960
Total liabilities and stockholders’ equity $ 132,682 $ 143,889

Boundless Bio Reports First Quarter 2025 Financial Results and Business Highlights

On May 9, 2025 Boundless Bio (Nasdaq: BOLD), a clinical-stage oncology company interrogating extrachromosomal DNA (ecDNA) biology to deliver transformative therapies to patients with previously intractable oncogene amplified cancers, reported financial results and business highlights for the fiscal quarter ended March 31, 2025 (Press release, Boundless Bio, MAY 9, 2025, View Source [SID1234652819]).

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"Boundless remains committed to delivering new therapeutic options to patients with high unmet need oncogene amplified cancers," said Zachary Hornby, President and CEO of Boundless Bio. "We look forward to providing a clinical data update on our BBI-355 program later this year. Additionally, we expect to nominate a development candidate for our novel Kinesin program by mid-year, with plans to submit an IND in the first half of 2026."

Research and Development Highlights and Upcoming Milestones

BBI-355, a novel, oral, potent CHK1 inhibitor designed to target replication stress in oncogene-amplified cancers


Enrollment is ongoing in the Phase 1/2 POTENTIATE trial. Preliminary clinical proof-of-concept safety and antitumor activity data are expected in the second half of 2025.

Novel Kinesin program targeting ecDNA segregation and inheritance


Boundless expects to nominate a development candidate for its preclinical program targeting a previously undrugged kinesin by mid-2025, with an investigational new drug (IND) submission planned for the first half of 2026.

Recent Data Presentations


Preclinical data from studies conducted with Boundless’s ribonucleotide reductase (RNR) inhibitor, BBI-825, were presented in an oral session at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting. These data suggest that the combination of BBI-825 with mutant-specific, pan, and multi-RAS targeting inhibitors delayed or prevented acquired resistance in colorectal cancer preclinical models. Boundless continues to preclinically evaluate BBI-825 in various treatment settings.

First Quarter 2025 Financial Results


Cash Position: Cash, cash equivalents, and short-term investments totaled $138.3 million as of March 31, 2025.

Research and Development (R&D) Expenses: R&D expenses were $12.1 million for the first quarter of 2025, compared to $13.1 million for the same period in 2024.

General and Administrative (G&A) Expenses: G&A expenses were $5.2 million for the first quarter of 2025, compared to $3.8 million for the same period in 2024.

Net Loss: Net loss totaled $15.8 million for the first quarter of 2025, compared to $15.4 for the same period in 2024.

AMGEN TO PRESENT AT THE BANK OF AMERICA MERRILL LYNCH GLOBAL HEALTHCARE CONFERENCE

On May 9, 2025 Amgen (NASDAQ:AMGN) reported it will present at the Bank of America Merrill Lynch Global Healthcare Conference at 9:20 a.m. PT on Wednesday, May 14, 2025. Peter Griffith, executive vice president and chief financial officer at Amgen, and Jay Bradner, executive vice president of Research and Development at Amgen, will present at the conference (Press release, Amgen, MAY 9, 2025, View Source [SID1234652818]). The webcast will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public.

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The webcast, as with other selected presentations regarding developments in Amgen’s business given by management at certain investor and medical conferences, can be found on Amgen’s website, www.amgen.com, under Investors. Information regarding presentation times, webcast availability and webcast links are noted on Amgen’s Investor Relations Events Calendar. The webcast will be archived and available for replay for at least 90 days after the event.