On May 26, 2021 Cue Biopharma, Inc. (Nasdaq: CUE), a clinical-stage biopharmaceutical company engineering a novel class of injectable biologics designed to selectively engage and modulate targeted T cells directly within the patient’s body, reported that it will present at the Jefferies Virtual Healthcare Conference being held June 1-4, 2021 (Press release, Cue Biopharma, MAY 26, 2021, https://cuebiopharma.gcs-web.com/news-releases/news-release-details/cue-biopharma-present-corporate-and-clinical-progress-update [SID1234608278]).

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Cue Biopharma will provide a corporate update highlighting clinical progress with CUE-101, representative of the CUE-100 series and the Company’s lead Immuno-STAT (Selective Targeting and Alteration of T cells) platform-based therapeutic, in clinical trials for the treatment of patients with HPV+ recurrent/metastatic head and neck cancer. The presentation will also focus on other platform developments as well as pipeline progress including CUE-102, Cue Biopharma’s drug candidate targeting Wilms Tumor 1 (WT1). CUE-102 is scheduled for an Investigational New Drug (IND) filing in 1H 2022.

Presentation Details
Jefferies Virtual Healthcare Conference
Date and Time: Thursday, June 3, 2021 at 8:30 a.m. EDT
Webcast link: https://protect-us.mimecast.com/s/ZywXCrkNz7tw9D5fLtfAM

A live and archived webcast of the presentation will be available in the Investors and Media section of the Company’s website at www.cuebiopharma.com. The webcast will be archived for 30 days.

On May 26, 2021 Luye Pharma Group announced that its holding subsidiary, Boan Biotech, reported that it has signed an agreement with AstraZeneca China regarding the promotion rights to the anticancer drug Boyounuo (Bevacizumab Injection), under which the former will grant to the latter exclusive promotion rights in the county markets across 21 provinces, municipalities and autonomous regions of China (Press release, Boan Biotech, MAY 26, 2021, View Source [SID1234595076]).

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The partnership is based on integrating the strengths and resources of both companies at various levels of markets in China. Boan Biotech will coordinate its own business team, commercial networks and resources in the field of oncology to ensure better access to Boyounuo for patients in key markets. In addition, Boan Biotech will join hands with AstraZeneca to leverage their many years of broad market coverage and channel development in China, especially at the county level, enabling more patients to benefit from the drug.

Boyounuo, a bio-antibody drug developed by Boan Biotech was recently approved for marketing by China’s National Medical Products Administration, for treating advanced, metastatic or recurrent non-small-cell lung cancer and metastatic colorectal cancer. To make it available to patients as quickly as possible, the company arranged the delivery of the first batch of product within ten days of announcing the official approval. Prescriptions have been issued in many cities across the country.

Ms. Hua Jiang, Chief Executive Officer of Boan Biotech said: "AstraZeneca has a broad range of innovative resources and a global network with years of development experience in the oncology therapeutic field and county markets. Our strategic collaboration with AstraZeneca provides an important supplement and extension to the commercial network for Boyounuo. We will leverage our respective strengths in channels and patient coverage at multiple market levels, as well as explore active collaboration opportunities in overseas markets, to provide high-quality and affordable drugs for more patients."

Mr. Leon Wang, Executive Vice President, International and China President at AstraZeneca said: "At AstraZeneca, patients are at the centre of everything we do. Deeply rooted in China county areas for many years, we work with various parties to ensure more patients benefit from innovative holistic disease management solutions. Boan Biotech is a comprehensive biopharmaceutical company with capabilities across the industry value chain, as well as excellent R&D and manufacturing teams. With their position as a leading local company, we are delighted to be working together and looking forward to our close collaboration in the future, bringing more innovative solutions to patients at the county level and expanding on continued efforts to meet the growing health needs in China."

On May 26, 2021 AXIM Biotechnologies, Inc. (OTCQB: AXIM) ("AXIM Biotech," "AXIM" or "the Company"), an international healthcare solutions company targeting oncological and COVID-19 research, reported that it has completed pre-clinical drug studies on its patent pending compound SPX-1009, demonstrating the suppression of malignant metastatic melanoma cells (Press release, AXIM Biotechnologies, MAY 26, 2021, View Source;utm_medium=rss&utm_campaign=axim-biotechnologies-completes-pre-clinical-drug-studies-on-spx-1009-compound-proving-suppression-of-melanoma-cells [SID1234585596]). The independent research was completed by Dr. Douglas Lake’s laboratory at Arizona State University.

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"We are extremely excited with the results of the in vitro testing," said John W. Huemoeller II, Chief Executive Officer of AXIM Biotechnologies, Inc. "This potential therapeutic treatment could someday help control melanoma growth and metastasis with our compound SPX-1009 in a topical treatment."

Melanoma is the most serious type of skin cancer because of its ability to spread to other organs rapidly if it is not treated at an early stage. According to SkinCancer.org, an estimated 207,390 cases of melanoma will be diagnosed in the U.S. in 2021 and an estimated 7,180 people will die of melanoma in the U.S. in 2021.

SPX-1009 was first screened in a cell-free enzymatic assay for its ability to inhibit Quiescin Sulfhydryl Oxidase I ("QSOX1"), a tumor-derived enzyme that is important for cancer growth, invasion and metastasis, and was then tested for its ability to inhibit growth and invasion of a well-established A375 melanoma cell line and a low-passage patient-derived melanoma. 2D invasion assays and 3D tumor spheroid assays were employed to measure the effect of the compounds on tumor invasion.

As a next step, AXIM intends to initiate animal studies to demonstrate the ability of SPX-1009 to suppress tumor growth and metastasis in a murine model of melanoma. AXIM’s intellectual property related to the SPX-1009 technology is the subject of numerous patent-pending applications.

For more information about AXIM, please visit www.aximbiotech.com.

On May 26, 2021 Oncorus, Inc. (Nasdaq: ONCR), a viral immunotherapies company focused on driving innovation to transform outcomes for cancer patients, reported that its President and Chief Executive Officer, Theodore (Ted) Ashburn, M.D., Ph.D., will present at the upcoming Jefferies Virtual Healthcare Conference on Wednesday, June 2, 2021 at 2:00 p.m. ET (Press release, Oncorus, MAY 26, 2021, View Source [SID1234584765]).

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A live webcast of the presentation will be available under the Investors & Media section of Oncorus’ website at View Source A replay of the presentation will be archived on Oncorus’ site for 30 days following the event.

On May 26, 2021 Concert Pharmaceuticals, Inc. (NASDAQ: CNCE) reported that it will participate at the following upcoming virtual investor conferences (Press release, Concert Pharmaceuticals, MAY 26, 2021, View Source [SID1234584686]):

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The Jefferies Virtual Healthcare Conference
Fireside Chat Presentation on June 2, 2021 at 3:30 p.m. ET
The JMP Securities Life Sciences Conference
Fireside Chat Presentation on June 16, 2021 at 11:30 a.m. ET
A live webcast of the presentations may be accessed in the Investors section of the Company’s website at www.concertpharma.com. Please log on to the Concert website approximately 15 minutes prior to the scheduled webcast to ensure adequate time for any software downloads that may be required. A replay of the webcasts will be available on Concert’s website for two weeks following the presentations.