LianBio Appoints Yizhe Wang, Ph.D., as Chief Executive Officer

On May 10, 2021 LianBio, a biotechnology company dedicated to bringing paradigm-shifting medicines to patients in China and other major Asian markets, reported Yizhe Wang, Ph.D., has been named Chief Executive Officer and appointed to the Board of Directors, effective May 17, 2021 (Press release, LianBio, MAY 10, 2021, View Source [SID1234579611]).

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"Yizhe is a strategic leader with decades of experience developing, launching and managing the product lifecycle of transformative drugs in China, the U.S. and Europe," said Konstantin Poukalov, Managing Director, Perceptive Advisors and Executive Chairman, LianBio. "With his proven leadership guiding late-stage assets to market in China, LianBio is well positioned for our next phase of growth as we continue to advance our pipeline and partner with leading global biopharmaceutical companies to expand their reach into China and other Asian markets."

Throughout Dr. Wang’s career as a pharmaceutical executive in China and the United States, he has built and overseen high-growth business units and played a key role in the development, approval and commercialization of more than 25 innovative medicines. With past experience spanning commercial, R&D and strategic leadership roles at Eli Lilly and GlaxoSmithKline (GSK), he brings to LianBio expertise in accelerating drug development and executing commercial launches.

"I am honored to join LianBio to scale the company’s next-generation approach to sourcing, developing and commercializing innovative drugs in the region," said Dr. Wang. "As LianBio continues to advance a portfolio of world class programs across therapeutic areas, I look forward to partnering with the founding team to address the medical needs of patients in China and throughout Asia."

Dr. Wang joins LianBio from Eli Lilly, where he most recently served as Global Brand Development Leader, Lilly Oncology. In 2020, Dr. Wang served as Global Platform Lead for anti-COVID Therapy, Lilly Research Lab, where he led a new operating model integrating discovery, development and launch resulting in the EUA of bamlanivimab. Previously, Dr. Wang was SVP, Head of BioMedicines and Oncology Businesses, Lilly China, where he was a member of the Global Oncology and Biomedicines Business Unit lead teams, and China Executive Committee. In this role, he oversaw a 1,000-person organization, delivered double digit sales growth and launched multiple new products, including Tyvyt, Elunate, Taltz and Olumiant. Prior to Eli Lilly, Dr. Wang was at GSK for 15 years where he held product and commercial strategy roles of increasing responsibility in the U.S. (2003-2012), U.K. (2012-2014) and China (2014-2018), ultimately serving as Head of GSK China Pharmaceuticals’ Respiratory Business Unit. Earlier in his career, he was a researcher at Bristol Myers Squibb.

Dr. Wang received a doctorate in organic chemistry from Yale University. He also earned a master’s degree in business administration from the Wharton School at the University of Pennsylvania and a bachelor’s degree in chemistry from Ramapo College of New Jersey.

Promega, Exact Sciences Partnering to Help Jumpstart Colorectal Cancer Screenings

On May 10, 2021 Promega Corporation reported that Serious runners and casual walkers alike are invited to join a month-long Get Your Rear in Gear – Madison run/walk virtual event during May to raise money and awareness for colorectal cancer screening efforts (Press release, Promega, MAY 10, 2021, View Source [SID1234579609]). Colorectal cancer is the nation’s No. 2 cancer killer, but it is up to 95% preventable with proper screening. The number of people being screened has dropped drastically worldwide since the start of the COVID-19 pandemic. The event is aimed to help encourage this important, life-saving health screening.

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"It is imperative that patients are encouraged to get back in with their primary doctor to get screening tests they may have missed," says Dr. Sam Lubner, an oncologist at the University of Wisconsin Carbone Cancer Center. "Without accurate diagnosis as early as possible, all of the advancements we have made in cancer research cannot be brought to bear for patients."

Get Your Rear in Gear – Madison is presented by Promega and Exact Sciences with the support of the Colon Cancer Coalition. This inaugural event is one of nearly 40 held annually across the country planned by local volunteers. Money raised will go to UW Carbone Cancer Center programs aimed at increasing colon cancer screening and early detection.

Registration is open during the entire month of May at www.ColonCancerCoalition.org/Madison. Event participation for colorectal cancer patients and survivors is free. Fundraising by participants is encouraged, but not required.

Centessa Pharmaceuticals Appoints One of the World’s Leading Drug Developers, Antoine Yver, M.D., M.Sc., as Chief Medical Officer

On May 10, 2021 Centessa Pharmaceuticals ("Centessa") reported that Antoine Yver, M.D., M.Sc., has been appointed as Chief Medical Officer (Press release, Centessa Pharmaceuticals, MAY 10, 2021, View Source [SID1234579608]). Dr. Yver is one of the world’s leading drug developers with more than 30 years of global experience in the pharmaceutical industry.

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"We are absolutely thrilled to welcome Antoine to our team as CMO," said Saurabh Saha, M.D., Ph.D., Chief Executive Officer of Centessa. "Antoine is a true industry leader with significant experience and success as a drug developer, having developed some of the most impactful oncology drugs in the world. I look forward to partnering with him as we advance our portfolio of preclinical programs into the clinic and progress our four assets currently in clinical development."

"I am delighted to be joining Centessa, a differentiated company with a unique operating model," said Dr. Yver. "Centessa’s asset-centric model exemplifies the very best practices that I have experienced and implemented in the industry. I am honored to be working with such a talented leadership team and exceptional Board and look forward to helping establish this bold new R&D enterprise while we strive to bring important new medicines to patients."

Dr. Yver brings more than 30 years of global experience in the pharmaceutical industry to Centessa and has played a pivotal role in the development and approvals of 11 different drugs, including Tagrisso, Lynparza, and Enhertu. He led the development of Tagrisso in 2 years 7 months from first human dose to U.S. approval and its rapid deployment to all other major regions, which was the fastest ever for an anti-cancer drug. Dr. Yver joins the company from Daiichi Sankyo, where he served as Executive Vice President and Global Head, R&D Oncology, and Chair of the Cancer Enterprise. Previously, Dr. Yver was with AstraZeneca, most recently serving as Senior Vice President, Global Medicine Head, Oncology, and Global Medicines Development China Lead. Earlier, he held various clinical development roles at Schering-Plough/Merck, Johnson & Johnson, Aventis Pharmaceuticals, Inc., Rhône-Poulenc Rorer, Inc, Applied Immune Sciences, Inc, and Chugai-RP. Dr. Yver is a pediatric oncologist and holds an M.D. from Université Paris-Saclay.

Eagle Pharmaceuticals Announces Filing of TREAKISYM (bendamustine) Rapid Infusion (“RI”) Liquid Formulation in Japan

On May 10, 2021 Eagle Pharmaceuticals, Inc. ("Eagle" or the "Company") (NASDAQ: EGRX) reported that TREAKISYM RI (50ml) liquid formulation has been filed with the Pharmaceuticals and Medical Devices Agency ("PMDA") in Japan (Press release, Eagle Pharmaceuticals, MAY 10, 2021, View Source [SID1234579607]).

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The application is based on the results of clinical studies investigating the safety and pharmacokinetics of TREAKISYM RTD administered by 10-minute intravenous infusion.

"We are pleased that the RI application has been submitted ahead of schedule, which will enable patients and providers alike to reap the benefits of this formulation. We believe we can get close to peak income of $20-$25 million as early as next year from the RTD and RI products. This is an important extension of the bendamustine franchise, and we value the relationship with Symbio," stated Scott Tarriff, Chief Executive Officer.

In September 2017, Eagle licensed to SymBio intellectual property necessary to develop, market and sell RTD and RI formulations of bendamustine under the trade name TREAKISYM in Japan utilizing Eagle’s proprietary technology. As part of the agreement, SymBio assumed responsibility for securing regulatory approval of the TREAKISYM RTD and RI products using the licensed technology in Japan.

TREAKISYM RI has the advantage of reducing infusion time to 10 minutes (from the current 60 minutes), eliminating the need for manual reconstitution and significantly reducing preparation time, benefitting both patients and healthcare providers.

Vertex to Present at the Bank of America Securities 2021 Virtual Health Care Conference on May 13

On May 10, 2021 Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) reported that management will present at the Bank of America Securities 2021 Virtual Health Care Conference on Thursday, May 13, 2021 at 10:15 a.m. ET (Press release, Vertex Pharmaceuticals, MAY 10, 2021, View Source [SID1234579606]).

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The audio portion of management’s remarks will be available live through Vertex’s website, www.vrtx.com in the "Investors" section under the "News and Events" page. A replay of the conference webcast will be archived on the company’s website.