On April 26, 2023 BeiGene (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global biotechnology company, reported that it will present data from its broad solid tumor and hematology portfolio at the upcoming American Society of Cancer Oncology (ASCO) (Free ASCO Whitepaper) Annual Meeting in Chicago, June 2-6, 2023 (Press release, BeiGene, APR 26, 2023, View Source [SID1234630512]).
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"Our accepted data presentations at ASCO (Free ASCO Whitepaper) demonstrate the resolve and productivity of BeiGene’s R&D team in our drive to improve treatment outcomes and access for patients worldwide," said Lai Wang, Ph.D., Global Head of R&D at BeiGene. "We look forward to joining the oncology community in Chicago and sharing progress as we continue to advance our rich pipeline of first-in-class and potentially best-in-class programs."
Data to be presented at ASCO (Free ASCO Whitepaper) include:
Abstract Title
Abstract #
Presentation Details
Lead Author
Solid Tumors
Results from the Pivotal Phase 2b HERIZON-BTC-01 Study: Zanidatamab in Previously-treated HER2 amplified Biliary Tract Cancer
4008
Oral presentation: Gastrointestinal Cancer— Gastroesophageal, Pancreatic, and Hepatobiliary
Fri., June 2,
2:45-5:45 p.m. CT
Shubham Pant
A phase 1 study of the OX40 agonist, BGB-A445, with or without tislelizumab, an anti-PD-1 monoclonal antibody, in patients with advanced solid tumors
2574
Poster presentation: Developmental Therapeutics—Immunotherapy
Sat., June 3,
8:00-11:00 a.m. CT
Jayesh Desai
Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: updated results from a Phase Ib/II study
1044
Poster presentation: Breast Cancer—Metastatic
Sun., June 4, 8:00-11:00 a.m. CT
Xiaojia Wang
Tislelizumab versus sorafenib in first-line treatment of unresectable hepatocellular carcinoma: the RATIONALE-301 European/North American subgroup
4082
Poster presentation: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Mon., June 5, 8:00-11:00 a.m. CT
Arndt Vogel
Impact of risk factors on overall survival in patients with unresectable hepatocellular carcinoma treated with first-line tislelizumab
4083
Poster presentation: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Mon., June 5, 8:00-11:00 a.m. CT
Masatoshi Kudo
AdvanTIG-105: phase 1b dose-expansion study of ociperlimab + tislelizumab with chemotherapy in patients with stage IV gastric/gastroesophageal adenocarcinoma
4028
Poster presentation: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Mon., June 5, 8:00-11:00 a.m. CT
Se Hyun Kim
Hematology
A phase 1 study evaluating the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of Bcl-2 inhibitor BGB-11417 in adult patients with mature B-cell malignancies
7558
Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Mon., June 5, 8:00-11:00 a.m. CT
Caixia Li
First interim analysis of a phase 1 study of zanubrutinib plus lenalidomide in patients with relapsed/refractory diffuse large B-cell lymphoma
7557
Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Mon., June 5, 8:00-11:00 a.m. CT
Huilai Zhang
Zanubrutinib plus obinutuzumab versus obinutuzumab in patients with relapsed/refractory follicular lymphoma: Updated analysis of the ROSEWOOD study
7545
Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Mon., June 5, 8:00-11:00 a.m. CT
Christopher Flowers
MAHOGANY: A phase 3 trial of zanubrutinib plus anti-CD20 antibodies vs lenalidomide plus rituximab in patients with relapsed or refractory follicular or marginal zone lymphoma
TPS7590
Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Mon., June 5, 8:00-11:00 a.m. CT
Loretta Nastoupil
Matching-adjusted indirect comparison of zanubrutinib versus ibrutinib in relapsed/refractory marginal zone lymphoma
e19527
Publication only
Catherine Thieblemont
Comparative efficacy of zanubrutinib versus rituximab in relapsed marginal zone lymphoma: matching-adjusted indirect comparison
e19526
Publication only
Catherine Thieblemont
Real-world treatment patterns of Bruton tyrosine kinase inhibitors in patients with mantle cell lymphoma in community oncology practices in the United States
e19525
Publication only
Bijal Shah