BeiGene to Highlight Broad Oncology Portfolio at the 2023 ASCO Annual Meeting

On April 26, 2023 BeiGene (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global biotechnology company, reported that it will present data from its broad solid tumor and hematology portfolio at the upcoming American Society of Cancer Oncology (ASCO) (Free ASCO Whitepaper) Annual Meeting in Chicago, June 2-6, 2023 (Press release, BeiGene, APR 26, 2023, View Source [SID1234630512]).

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"Our accepted data presentations at ASCO (Free ASCO Whitepaper) demonstrate the resolve and productivity of BeiGene’s R&D team in our drive to improve treatment outcomes and access for patients worldwide," said Lai Wang, Ph.D., Global Head of R&D at BeiGene. "We look forward to joining the oncology community in Chicago and sharing progress as we continue to advance our rich pipeline of first-in-class and potentially best-in-class programs."

Data to be presented at ASCO (Free ASCO Whitepaper) include:

Abstract Title

Abstract #

Presentation Details

Lead Author

Solid Tumors

Results from the Pivotal Phase 2b HERIZON-BTC-01 Study: Zanidatamab in Previously-treated HER2 amplified Biliary Tract Cancer

4008

Oral presentation: Gastrointestinal Cancer— Gastroesophageal, Pancreatic, and Hepatobiliary

Fri., June 2,

2:45-5:45 p.m. CT

Shubham Pant

A phase 1 study of the OX40 agonist, BGB-A445, with or without tislelizumab, an anti-PD-1 monoclonal antibody, in patients with advanced solid tumors

2574

Poster presentation: Developmental Therapeutics—Immunotherapy

Sat., June 3,

8:00-11:00 a.m. CT

Jayesh Desai

Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: updated results from a Phase Ib/II study

1044

Poster presentation: Breast Cancer—Metastatic

Sun., June 4, 8:00-11:00 a.m. CT

Xiaojia Wang

Tislelizumab versus sorafenib in first-line treatment of unresectable hepatocellular carcinoma: the RATIONALE-301 European/North American subgroup

4082

Poster presentation: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary

Mon., June 5, 8:00-11:00 a.m. CT

Arndt Vogel

Impact of risk factors on overall survival in patients with unresectable hepatocellular carcinoma treated with first-line tislelizumab

4083

Poster presentation: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary

Mon., June 5, 8:00-11:00 a.m. CT

Masatoshi Kudo

AdvanTIG-105: phase 1b dose-expansion study of ociperlimab + tislelizumab with chemotherapy in patients with stage IV gastric/gastroesophageal adenocarcinoma

4028

Poster presentation: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary

Mon., June 5, 8:00-11:00 a.m. CT

Se Hyun Kim

Hematology

A phase 1 study evaluating the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of Bcl-2 inhibitor BGB-11417 in adult patients with mature B-cell malignancies

7558

Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Mon., June 5, 8:00-11:00 a.m. CT

Caixia Li

First interim analysis of a phase 1 study of zanubrutinib plus lenalidomide in patients with relapsed/refractory diffuse large B-cell lymphoma

7557

Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Mon., June 5, 8:00-11:00 a.m. CT

Huilai Zhang

Zanubrutinib plus obinutuzumab versus obinutuzumab in patients with relapsed/refractory follicular lymphoma: Updated analysis of the ROSEWOOD study

7545

Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Mon., June 5, 8:00-11:00 a.m. CT

Christopher Flowers

MAHOGANY: A phase 3 trial of zanubrutinib plus anti-CD20 antibodies vs lenalidomide plus rituximab in patients with relapsed or refractory follicular or marginal zone lymphoma

TPS7590

Poster presentation: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Mon., June 5, 8:00-11:00 a.m. CT

Loretta Nastoupil

Matching-adjusted indirect comparison of zanubrutinib versus ibrutinib in relapsed/refractory marginal zone lymphoma

e19527

Publication only

Catherine Thieblemont

Comparative efficacy of zanubrutinib versus rituximab in relapsed marginal zone lymphoma: matching-adjusted indirect comparison

e19526

Publication only

Catherine Thieblemont

Real-world treatment patterns of Bruton tyrosine kinase inhibitors in patients with mantle cell lymphoma in community oncology practices in the United States

e19525

Publication only

Bijal Shah