On June 7, 2017 BeiGene, Ltd. (NASDAQ:BGNE), a clinical-stage biopharmaceutical company developing innovative molecularly targeted and immuno-oncology drugs for the treatment of cancer, reported that it will present updates on its BTK inhibitor BGB-3111 in three oral presentations and a poster at the upcoming 14th International Conference on Malignant Lymphoma (14-ICML) (Press release, BeiGene, JUN 7, 2017, View Source [SID1234519469]). 14-ICML will take place June 14-17, 2017, in Lugano, Switzerland. Following its presentations, BeiGene will host an investor call and webcast to discuss the presented data and development program. Schedule your 30 min Free 1stOncology Demo! Oral Presentation, Abstract # 059
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Title: Bruton’s Tyrosine Kinase (BTK) Inhibitor BGB-3111 Demonstrates High Very Good Partial Response (VGPR) Rate in Patients with Waldenström Macroglobulinemia (WM)
Presenter: Dr. Judith Trotman
Session: Session 4 – Targeting the BCR Pathways
Date & Time: Thursday, June 15, 2017, 4:00 PM CEST
Location: Room A, Cinema Corso and Aula Magna (Lugano University)
Oral Presentation, Abstract # OT06
Title: A Head-to-Head Phase 3 Study Comparing BGB-3111 and Ibrutinib in Patients with Waldenström Macroglobulinemia
Presenter: Dr. Christian Buske
Session: Ongoing Trials
Date & Time: Thursday, June 15, 2017, 6:05 PM CEST
Location: Auditorium (Lugano University)
Oral Presentation, Abstract # 103
Title: Safety and Activity of the Highly Specific BTK Inhibitor, BGB-3111 Plus Obinutuzumab in Patients (Pts) with Follicular Lymphoma (FL) and Chronic Lymphocytic Leukemia (CLL)
Presenter: Dr. Constantine Tam
Session: Session 7 – Advances in CLL
Date & Time: Friday, June 16, 2017, 11:50 AM CEST
Location: Room A, B, Marquee, Cinema Corso and Aula Magna (Lugano University)
Poster, Abstract # 237
Title: High Overall Response Rate with the BTK Inhibitor BGB-3111 in Patients with Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma: An Update on Safety and Activity
Presenter: Dr. John Seymour
Session Dates & Times: Wednesday, June 14, 12:30-6:30 PM CEST; Thursday, June 15, 8:30-6:30 PM CEST; Friday, June 16, 8:30-6:30 PM CEST
Location: Marquee
Investor Conference Call
Date & Time: Friday, June 16, 2017, 2:00 PM CEST (8:00 AM EDT, 8:00 PM China Standard Time)
Dial-in Numbers: 1-845-675-0437 or 1-866-519-4004 (US), 400-620-8038 or 800-819-0121 (China), +852 30186771 (Hong Kong), or +65 67135090 (International)
Conference ID Number: 33044427
A live webcast and replay will be available on BeiGene’s investor website, View Source The dial-in replay will be available approximately two hours after the conference and will be available for two days following the event. It can be accessed by dialing 1-646-254-3697 (US), 400-632-2162 (China), +852 30512780 (Hong Kong), or +61 2 8199 0299 (International).
About BGB-3111
BGB-3111 is a potent and highly selective investigational small molecule inhibitor of BTK. BGB-3111 has demonstrated higher selectivity against BTK than ibrutinib (the only BTK inhibitor currently approved by the U.S. Food and Drug Administration and the European Medicines Agency) based on biochemical assays, higher exposure than ibrutinib based on their respective Phase I experience, and sustained 24-hour BTK occupancy in both the blood and the lymph node.