On May 15, 2019 Bellicum Pharmaceuticals, Inc. (NASDAQ:BLCM), a leader in developing novel, controllable cellular immunotherapies for cancers and orphan inherited blood disorders, reported that its abstract for BPX-601 has been accepted for poster presentation at the 2019 American Society for Clinical Oncology (ASCO) (Free ASCO Whitepaper) Annual Meeting (Press release, Bellicum Pharmaceuticals, MAY 15, 2019, View Source [SID1234536323]). The meeting is being held May 31 – June 4, 2019 in Chicago.
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Details of the poster presentation are as follows:
Title: Ligand-Inducible, Prostate Stem Cell Antigen (PSCA)-Directed GoCAR-T Cells in Advanced Solid Tumors: Preliminary Results with Cyclophosphamide (Cy) ± Fludarabine (Flu) Lymphodepletion (LD)
Poster Board: #180-Abstract 2536
Presenter: Carlos R. Becerra, M.D.
Time/Location: Saturday, June 1, 8 to 11 a.m. CDT, Hall A, Poster Session – Developmental Immunotherapy and Tumor Immunobiology
About BPX-601
BPX-601, the company’s first GoCAR-T product candidate, incorporates iMC, Bellicum’s inducible co-activation domain. iMC (inducible MyD88/CD40) is designed to provide a powerful boost to T cell proliferation and persistence and enable the CAR-T to override key immune inhibitory mechanisms, including PD-1 and TGF-beta. BPX-601 is being evaluated as a treatment for solid tumors expressing prostate stem cell antigen (PSCA), including pancreatic, gastric, and prostate cancers.