On October 3, 2023 BostonGene, a leading provider of AI-based molecular and immune profiling solutions, reported a master agreement with Johns Hopkins University School of Medicine (JHUSOM) to collaborate on multiple clinical research projects (Press release, BostonGene, OCT 3, 2023, View Source [SID1234635615]). The agreement allows BostonGene and JHUSOM to further identify and validate novel precision medicine approaches.
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JHUSOM will work with BostonGene on the molecular characterization study of the patient’s tumor, microenvironment and immune system and its predictive value in response to treatment. BostonGene’s solution will provide JHUSOM with detailed analysis, interpretation and visualization of big data obtained from cancer patient’s genomic, transcriptomic, proteomic and imaging studies. This work hopes to identify significant somatic alterations, evaluate protein expression, compute tumor clonality, tumor heterogeneity, tumor microenvironment cell type composition, hereditary predisposition, viral infestation and pharmacogenomics and predict neoantigens for personalized vaccine development, among other molecular features. BostonGene will perform comprehensive bioinformatics to validate hypothesis-driven research to identify targetable molecular alterations.
"We’re honored to collaborate with JHUSOM to provide our AI-based molecular and immune profiling techniques that comprehensively analyze the tumor, microenvironment, and immune system to uncover treatable targets to personalize therapy for patients," said Nathan Fowler, MD, Chief Medical Officer at BostonGene. "This collaboration supports our mission to support doctors in finding the most effective strategy for personalized treatment options for their patients."