On April 10, 2019 Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (TASE:CFBI), a biotechnology company with a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, reported that a late-breaking abstract detailing results from the Company’s recently completed multicenter Phase II trial in patients with advanced liver cancer has been accepted for oral presentation at the late-breaking abstract session of the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO) (Free ASCO Whitepaper) (Press release, Can-Fite BioPharma, APR 10, 2019, View Source [SID1234535093]). The world’s largest clinical cancer research meeting, ASCO (Free ASCO Whitepaper), will take place from May 31 to June 4, 2019 in Chicago, Illinois.
Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:
Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing
Schedule Your 30 min Free Demo!
The abstract titled: "A phase II, randomized, double-blind, placebo-controlled trial evaluating efficacy and safety of namodenoson (CF102), an a3 adenosine receptor agonist (A3AR), as a second-line treatment in patients with Child-Pugh B (CPB) advanced hepatocellular carcinoma (HCC)", will be presented in an oral session by Prof. Salomon Stemmer, Principal Investigator of the Phase II trial.
Oral Abstract Presentation Details
Date: Tuesday, June 02, 2019
Time: 8:00 am CDT
Oral abstract session: Developmental Immunotherapy and Tumor Immunobiology
"We consider ASCO (Free ASCO Whitepaper)’s acceptance of our late breaking oral presentation a testament to the compelling data coming out of our recently completed Phase II study of Namodenoson. We believe this reflects the oncology community’s assessment that our Phase II Namodenoson trial is a high-impact study with significant relevance in the treatment of liver cancer," stated Can-Fite CEO Pnina Fishman.
Can-Fite is currently designing and planning the protocol for a Phase III study with the support of the world’s leading oncologists and regulatory experts including Dr. Josep Llovet, Founder and Director of the Liver Cancer Program and Full Professor of Medicine at the Mount Sinai School of Medicine, New York, a key opinion leader who will serve as the Phase III study’s Principal Investigator.
About Namodenoson
Namodenoson is a small orally bioavailable drug that binds with high affinity and selectivity to the A3 adenosine receptor (A3AR). Namodenoson is being evaluated as a second line treatment for hepatocellular carcinoma, with a recently completed Phase II trial and planned Phase III trial in this indication. The drug is currently in an ongoing Phase II trial as a treatment for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). A3AR is highly expressed in diseased cells whereas low expression is found in normal cells. This differential effect accounts for the excellent safety profile of the drug.