InduPro Therapeutics Announces Strategic Collaboration with Lilly to Develop First-in-Class Bispecific/Multispecific Oncology Therapeutics Using InduPro’s Proximity-Guided Platform

On January 7, 2026 InduPro, Inc., a biotechnology company defining membrane protein spatial relationships to create novel therapeutics for the treatment of cancer and autoimmune diseases, reported a global strategic collaboration and licensing agreement, and equity investment, with Eli Lilly and Company ("Lilly") to discover novel oncology treatments using InduPro’s proximity-guided platform.

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Under the terms of the agreement, the two companies will collaborate on up to three targets, for a total deal value of up to approximately $950M. Lilly will also make an equity investment in InduPro.

By leveraging Tumor Associated Proximity Antigens (TAPAs), surface antigens that are spatially co-localized and often functionally linked to tumor-associated antigens (TAAs) within the tumor microenvironment, the companies will use InduPro’s proximity-based platform to discover novel, disease-specific protein-target pairs. This strategy is designed to enable new therapeutic approaches for bispecific antibody drug conjugates (ADCs) and multispecific T-cell engagers, offering improved safety, potency, and tumor selectivity.

"Our partnership with Lilly underscores a shared commitment to advancing a new generation of tumor-selective medicines guided by the spatial biology of cancer," said Prakash Raman, PhD, CEO of InduPro. "TAPAs represent a fundamentally new way to think about tumor antigens, and we’re thrilled that Lilly shares our vision of leveraging proximity-based biology to enable precision multi-specific therapeutics. We believe this partnership reflects growing confidence in our differentiated, proximity-guided approach to tumor targeting and its promise to improve the design and performance of ADCs and TCEs."

Through the agreement, Lilly will gain access to InduPro’s proprietary AI/ML-enabled membrane interactomics (MInt) platform. InduPro will lead early discovery efforts, applying its proximity-guided platform to identify co-target pairs and advance bispecific and multispecific antibody programs emerging from the collaboration.

(Press release, InduPro, JAN 7, 2026, View Source [SID1234661824])

AMGEN TO PRESENT AT THE 44TH ANNUAL J.P. MORGAN HEALTHCARE CONFERENCE

On January 7, 2026 Amgen (NASDAQ:AMGN) reported it will present at the 2026 J.P. Morgan Healthcare Conference at 3:45 p.m. PT on Monday, January 12, 2026. Robert A. Bradway, chairman and chief executive officer at Amgen, will present at the conference. The webcast will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public.

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The webcast, as with other selected presentations regarding developments in Amgen’s business given by management at certain investor and medical conferences, can be found on Amgen’s website, www.amgen.com, under Investors. Information regarding presentation times, webcast availability and webcast links are noted on Amgen’s Investor Relations Events Calendar. The webcast will be archived and available for replay for at least 90 days after the event.

(Press release, Amgen, JAN 7, 2026, View Source [SID1234661794])

RAPT Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference

On January 7, 2026 RAPT Therapeutics, Inc. (Nasdaq: RAPT), a clinical-stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing novel therapies for patients living with inflammatory and immunological diseases, reported that Brian Wong, M.D., Ph.D., President and Chief Executive Officer, will present a company overview at the 44thAnnual J.P. Morgan Healthcare Conference on Wednesday, January 14, 2026 at 2:15 p.m. Pacific Time.

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To access the live webcast or subsequent archived recording of the presentation, please visit the RAPT Therapeutics website at https://investors.rapt.com/events-and-presentations.

(Press release, RAPT Therapeutics, JAN 7, 2026, https://investors.rapt.com/news-releases/news-release-details/rapt-therapeutics-present-44th-annual-jp-morgan-healthcare [SID1234661810])

Volastra Therapeutics Expands Clinical Development Program Following Encouraging KIF18A Inhibitor Data and Appoints New Chief Medical Officer to Lead Clinical Strategy

On January 7, 2026 Volastra Therapeutics, a clinical-stage biotechnology company pioneering first-in-class therapies targeting chromosomal instability (CIN) in cancer, reported a significant expansion of its clinical development program driven by encouraging clinical data from its lead KIF18A inhibitor (KIF18Ai), a key investigational CIN-targeted cancer therapy. The company also highlighted continued advancement across its strategic pipeline and the appointment of Timothy Bowler, M.D., Ph.D., as its new Chief Medical Officer, strengthening its leadership team as it executes on key value-inflection milestones.

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"These developments represent a meaningful step forward for Volastra as we continue to build a differentiated oncology company focused on chromosomal instability," said David Southwell, Chief Executive Officer of Volastra Therapeutics. "The strength of the emerging clinical data from our KIF18Ai program reinforces our conviction in CIN as a compelling therapeutic target and supports the expansion of our clinical strategy. With continued progress across our pipeline and the addition of our highly experienced Chief Medical Officer, we are well-positioned to execute on key upcoming milestones and create long-term value for patients and shareholders."

In addition to the company’s progress with its KIF18Ai ovarian cancer clinical program:

Expansion into New Tumor Types: It is also extending its Phase 1/2 program beyond ovarian cancer, with additional efficacy data from expansion cohorts expected in the first half of 2026.
KIF18Ai Combination Trials: The company is advancing new combination therapy studies with standards of care based on synergistic efficacy with taxanes in preclinical studies. Volastra plans to initiate its first combination trial in the first quarter of 2026, evaluating a KIF18Ai in combination with standard-of-care chemotherapy in patients with ovarian, lung, and breast cancers. Initial safety data are anticipated in the second quarter, with efficacy data expected to emerge in the second half of the year.
Biomarker Approach: In parallel, the company will continue to advance its biomarker identification strategy to predict KIF18Ai response, with results expected throughout the first half of 2026.
FDA Regulatory Update: Volastra also anticipates an End-of-Phase meeting with the FDA in the second half of 2026 to discuss potential registrational trials, reflecting the continued clinical momentum of the program.
These initiatives build on VLS-1488’s Phase 1 clinical results and follow the program’s FDA Fast Track designation in platinum-resistant ovarian cancer. To date, more than 120 patients have been treated with VLS-1488, which has been well tolerated across all dose levels with no dose-limiting toxicities observed. The company has demonstrated a clear dose-response across dose levels, with strong early efficacy and a favorable safety profile in platinum-resistant ovarian cancer. Notably, VLS-1488 has also demonstrated durable clinical benefit, with approximately half of patients with squamous non-small cell lung cancer remaining on therapy beyond six months.

To support its pipeline growth, Volastra has appointed Timothy Bowler, M.D., Ph.D., as Chief Medical Officer. He will oversee the expanded clinical program and drive the execution of the company’s development strategy. Dr. Bowler succeeds Dr. Scott Druttman, who is leaving Volastra to pursue other opportunities.

"Tim has been instrumental in driving our clinical progress, and we are delighted to have him step into the CMO role," said Mr. Southwell. "His expertise in oncology drug development will be invaluable as we advance our pipeline and strive to deliver CIN-targeted therapies to patients."

Dr. Bowler, a board-certified medical oncologist and experienced drug developer, previously served as Volastra’s Vice President of Clinical Development. Prior to joining Volastra in 2023, Dr. Bowler was Global Clinical Lead in oncology at Pfizer, and previously served at Regeneron and Memorial Sloan Kettering Cancer Center. In his new role, he will spearhead all clinical strategy and operations, guiding the KIF18Ai program through its next phase of growth and advancing Volastra’s broader clinical portfolio.

"Volastra’s innovative approach to targeting chromosomal instability has tremendous potential to benefit patients," said Timothy Bowler, M.D., Ph.D., Chief Medical Officer of Volastra. "Our focus now is executing a disciplined development plan that builds on monotherapy activity while expanding the reach of KIF18Ai through combinations and biomarker-guided approaches."

(Press release, Volastra Therapeutics, JAN 7, 2026, View Source [SID1234661825])

Artios to Present at the 44th Annual J.P. Morgan Healthcare Conference

On January 7, 2026 Artios Pharma Limited ("Artios"), a biopharmaceutical company committed to realizing the therapeutic power of targeting the DNA damage response ("DDR") in cancer, reported that it will present at the 44th Annual J.P. Morgan Healthcare Conference taking place in San Francisco from January 12 to 15, 2026.

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Mike Andriole, Artios’ Chief Executive Officer, will highlight the company’s strategic priorities for its two differentiated, potential first-in-class clinical programs in cancers with high unmet need. The company’s ATR inhibitor, alnodesertib, selects for ATM-deficient patients whose tumors harbor high degrees of DNA replication stress where the program has generated responses across eight different tumor types in early clinical development. It is currently being evaluated in two Phase 2 expansion cohorts in colorectal and pancreatic cancers. The company is also initiating a randomized Phase 2 study of its potentially first-in-class DNA polymerase Theta (Polθ) inhibitor, ART6043, in patients with BRCA-mutant HER2-negative breast cancer who are eligible to receive a PARP inhibitor.

The presentation will take place on Thursday, January 15, at 07:30 am PST (10:30 am EST / 03:30 pm UTC) in the Elizabethan B room (2nd floor) at The Westin St. Francis, 335 Powell Street, San Francisco.

(Press release, Artios Pharma, JAN 7, 2026, View Source [SID1234661795])