Transactions with shares and linked securities in Genmab A/S made by managerial employees and their closely associated persons

On May 3, 2021 Genmab A/S (Nasdaq: GMAB) reported that In accordance with Article 19 of Regulation No. 596/2014 on Market Abuse and Implementing Regulation 2016/523, this document discloses the data of the transactions made in Genmab A/S (Nasdaq: GMAB) made by managerial employees and their closely associated persons (Press release, Genmab, MAY 3, 2021, View Source [SID1234579001]).

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The company’s managerial employees and their closely associated persons have given Genmab A/S power of attorney on their behalf to publish trading in Genmab shares by the company’s managerial employees and their closely associated persons.

XOMA Earns Milestone for First Patient Dosed in Phase 3 Development Program

On May 3, 2021 XOMA Corporation (Nasdaq: XOMA) ("XOMA" or the "Company") reported it has earned a $0.5 million milestone from Janssen Biotech, Inc. (Janssen), as a result of the first patient dosed in a Phase 3 clinical trial evaluating one of Janssen’s biologic assets (Press release, Xoma, MAY 3, 2021, View Source [SID1234579017]).

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"Since 2017, our milestone and royalty portfolio has seen 27 advancements from one phase of development to the next. Each advance increases the potential value of the asset, as it moves closer to a possible regulatory approval and market launch. Cetrelimab is the second molecule to advance to Phase 3 development since we pivoted to become a biotech royalty aggregator in 2017," stated Jim Neal, Chief Executive Officer at XOMA. "We congratulate Janssen on reaching this important step and wish them continued success in their clinical development endeavors."

Under the terms of the agreement with Janssen, XOMA has the potential to receive additional regulatory milestone payments should Janssen achieve marketing approval, and upon commercialization, the Company will receive a royalty on future commercial sales. Should Janssen expand its late-stage development activities beyond the targeted indication, XOMA could receive additional milestone economics.

Herantis Pharma to Participate in the Upcoming Virtual Conferences

On May 3, 2021 Herantis Pharma Plc ("Herantis"), focusing on disease modifying therapies for debilitating neurodegenerative diseases, reported that Dr. Craig Cook, Chief Executive Officer, will hold 1×1 meetings and have a digital company presentation at the following virtual investor conferences (Press release, Herantis Pharma, MAY 3, 2021, View Source,c3338722 [SID1234578960]).

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Event Details:

Redeye Investor Forum Online

Date: 11 May 2021

Bio€quity Europe

Dates: 17 – 19 May 2021

ABGSC Life Science Summit

Date: 25 May 2021

Presentation Time: 11:00 – 11:30 a.m. CEST / 12:00 – 12:30 EEST

All presentations will be available via a digital library, which is accessible to event participants only. Please contact the organizers at the Redeye, Bio€quity Europe, and ABGSC if you wish to attend and/or schedule a meeting with Herantis.

Lilly Declares Second-Quarter 2021 Dividend and Announces Additional Share Repurchase Authorization

On May 3, 2021 The board of directors of Eli Lilly and Company (NYSE: LLY) (the "Board") reported that it has declared a dividend for the second quarter of 2021 of $0.85 per share on outstanding common stock (Press release, Eli Lilly, MAY 3, 2021, View Source [SID1234579002]). The dividend is payable on June 10, 2021 to shareholders of record at the close of business on May 14, 2021.

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The Board has also authorized the repurchase of up to an additional $5 billion of the company’s common stock. This repurchase authorization is in addition to the authorization remaining under the share repurchase program authorized by the Board in June 2018. As of March 31, 2021, there was $1 billion remaining under the 2018 share repurchase program.

Purchases may be made from time to time at management’s discretion. The share repurchase authorizations permit shares to be repurchased in a variety of methods, including open market purchases, accelerated share repurchases, or other privately negotiated transactions. The share repurchase authorizations have no time limit and may be suspended or discontinued at any time.

Sesen Bio to Host Conference Call to Review First Quarter 2021 Financial Results and Provide Business Update on Monday, May 10, 2021

On May 3, 2021 Sesen Bio (Nasdaq: SESN), a late-stage clinical company developing targeted fusion protein therapeutics for the treatment of patients with cancer, reported that the Company’s management team will host a conference call to review operating results for the first quarter ended March 31, 2021 and provide a business update (Press release, Sesen Bio, MAY 3, 2021, https://ir.sesenbio.com/news-releases/news-release-details/sesen-bio-host-conference-call-review-first-quarter-2021 [SID1234579019]). The conference call is scheduled for Monday, May 10, 2021 at 8:00 am ET.

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To participate in the conference call, please dial (844) 831-3025 (domestic) or (315) 625-6887 (international) and refer to conference ID 6229838. The webcast can be accessed in the Investor Relations section of the company’s website at www.sesenbio.com. The replay of the webcast will be available in the investor section of the company’s website at www.sesenbio.com for 60 days following the call.

About Vicineum

Vicineum, a locally administered fusion protein, is Sesen Bio’s lead product candidate being developed for the treatment of BCG-unresponsive non-muscle invasive bladder cancer (NMIBC). Vicineum is comprised of a recombinant fusion protein that targets epithelial cell adhesion molecule (EpCAM) antigens on the surface of tumor cells to deliver a potent protein payload, Pseudomonas Exotoxin A. Vicineum is constructed with a stable, genetically engineered peptide tether to ensure the payload remains attached until it is internalized by the cancer cell, which is believed to decrease the risk of toxicity to healthy tissues, thereby improving its safety. In prior clinical trials conducted by Sesen Bio, EpCAM has been shown to be overexpressed in NMIBC cells with minimal to no EpCAM expression observed on normal bladder cells. Sesen Bio is currently in the follow-up stage of a Phase 3 registration trial in the US for the treatment of BCG-unresponsive NMIBC. In February 2021, the FDA accepted for filing the Company’s BLA for Vicineum for the treatment of BCG-unresponsive NMIBC and granted the application Priority Review with a target PDUFA date of August 18, 2021. Additionally, Sesen Bio believes that cancer cell-killing properties of Vicineum promote an anti-tumor immune response that may potentially combine well with immuno-oncology drugs, such as checkpoint inhibitors. For this reason, the activity of Vicineum in BCG-unresponsive NMIBC is also being explored at the US National Cancer Institute in combination with AstraZeneca’s immune checkpoint inhibitor durvalumab.