AETERNA ZENTARIS ANNOUNCES $4.5 MILLION REGISTERED DIRECT OFFERING PRICED AT-THE-MARKET

On February 19, 2020 Aeterna Zentaris Inc. (NASDAQ: AEZS) (TSX: AEZS) ("Aeterna" or the "Company"), a specialty biopharmaceutical company commercializing and developing therapeutics and diagnostic tests, reported that it has entered into a securities purchase agreement with several institutional investors in the United States providing for the sale and issuance of approximately 3,478,261 common shares at a purchase price of $1.29375 per common share in a registered direct offering priced at-the-market under Nasdaq rules (Press release, AEterna Zentaris, FEB 19, 2020, View Source [SID1234554539]). The offering is expected to result in gross proceeds to Aeterna Zentaris of approximately $4.5 million.

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Aeterna Zentaris will also issue to the purchasers unregistered warrants to purchase up to an aggregate of 2,608,696 common shares. The warrants will be exercisable for a period of five and one-half years, exercisable immediately following the issuance date and have an exercise price of $1.20 per common share.

H.C. Wainwright & Co. is acting as the exclusive placement agent for the offering.

The registered direct offering and concurrent private placement is expected to close on or about February 21, 2020, subject to the satisfaction of customary closing conditions.

The common shares described above (but not the warrants or the common shares underlying the warrants) are being offered by Aeterna Zentaris pursuant to a "shelf" registration statement on Form F-3 (File No. 333-232935), which was previously declared effective by the U.S. Securities and Exchange Commission ("SEC") on August 15, 2019. Such common shares may be offered only by means of a prospectus, including a prospectus supplement, forming a part of the effective registration statement.

A prospectus supplement relating to the common shares will be filed by Aeterna with the SEC. When filed with the SEC, copies of the prospectus supplement and the accompanying prospectus relating to the registered direct offering, may be obtained at the SEC’s website at www.sec.gov. Electronic copies of the prospectus supplement and accompanying prospectus relating to the registered direct offering may also be obtained by contacting H.C. Wainwright & Co., LLC, 430 Park Avenue, 3rd Floor, New York, NY 10022, by telephone at (646) 975-6996 or by email at [email protected].

The warrants described above were offered in a private placement pursuant to an exemption from the Securities Act of 1933, as amended (the "Act"), and along with the common shares issuable upon their exercise, have not been registered under the Act, and may not be offered or sold in the United States absent registration with the SEC or an applicable exemption from such registration requirements.

This press release does not constitute an offer to sell or the solicitation of an offer to buy, nor will there be any sales of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such jurisdiction. No Canadian prospectus has been or will be filed in a province or territory of Canada to qualify the common shares or the warrants in connection with the offering.

AbbVie to Present at the Cowen 40th Annual Health Care Conference

On February 19, 2020 AbbVie (NYSE: ABBV), a research-based global biopharmaceutical company, reported that it will participate in the Cowen 40th Annual Health Care Conference on Wednesday, March 4, 2020. Michael Severino, M.D., vice chairman and president and Robert A. Michael, executive vice president and chief financial officer, will present at 10:20 a.m. Central time (Press release, AbbVie, FEB 19, 2020, https://news.abbvie.com/news/press-releases/abbvie-to-present-at-cowen-40th-annual-health-care-conference.htm [SID1234554487]).

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A live audio webcast of the presentation will be accessible through AbbVie’s Investor Relations website at investors.abbvie.com. An archived edition of the session will be available later that day.

Kura Oncology to Participate in Three Upcoming Investor Conferences

On February 19, 2020 Kura Oncology, Inc. (Nasdaq: KURA), a clinical-stage biopharmaceutical company focused on the development of precision medicines for the treatment of cancer, reported that Troy Wilson, Ph.D., J.D., President and Chief Executive Officer, is scheduled to participate in three upcoming investor conferences (Press release, Kura Oncology, FEB 19, 2020, View Source [SID1234554504]):

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A fireside chat at the SVB Leerink 9th Annual Global Healthcare Conference in New York at 11:30 a.m. ET / 8:30 a.m. PT on February 26, 2020;

A presentation at the Cowen 40th Annual Health Care Conference in Boston at 8 a.m. ET / 5 a.m. PT on March 3, 2020; and

A presentation at the Oppenheimer 30th Annual Healthcare Conference in New York at 10:20 a.m. ET / 7:20 a.m. PT on March 17, 2020.
Live audio webcasts of the fireside chat and presentations will be available in the Investors section of Kura’s website at www.kuraoncology.com, with an archived replay available for 30 days following the event.

Humanetics Corporation Acquires Manufacturing Assets for Radioprotectant Drug

On February 19, 2020 Humanetics Corporation (Humanetics) reported that it has entered into a definitive agreement with DSM Nutritional Products Ltd of Kaiseraugst Switzerland to acquire all of DSM’s assets related to the manufacture of the active pharmaceutical ingredient (API) in BIO 300, a clinical stage drug being developed by Humanetics for oncology and biodefense applications (Press release, Humanetics, FEB 19, 2020, View Source [SID1234554521]). DSM developed and patented a method to produce a highly pure form of the API.

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Included in the acquisition are patents, trademarks, trade secret manufacturing processes, analytical methods, regulatory filings, and a large number of nonclinical and clinical safety studies. Humanetics plans to transfer the manufacturing process to a site in the United States.

BIO 300 is a clinical stage drug under development to protect normal tissues from the harm caused by radiation. The drug’s radioprotective effects were originally discovered by researchers within the Department of Defense at the Armed Forces Radiobiology Research Institute. Humanetics has received significant federal funding to continue advancement of BIO 300 toward FDA approval. Humanetics has also initiated clinical studies for the use of BIO 300 to reduce the toxicity of radiation used in cancer treatment.

"We have had a long and successful collaboration with DSM, and we are excited to add these important assets to our BIO 300 program," said John Dykstra, Chief Operating Officer at Humanetics. "The assets we are acquiring from DSM will allow us to control and protect our entire manufacturing process from start to finish."

Aclaris Therapeutics to Announce Fourth Quarter and Full Year 2019 Financial Results on February 25, 2020

On February 19, 2020 Aclaris Therapeutics, Inc. (NASDAQ: ACRS) a physician-led biopharmaceutical company focused on immuno-inflammatory diseases, reported it will report financial results for the fourth quarter and full year 2019, Tuesday, February 25th, after U.S. financial markets close (Press release, Aclaris Therapeutics, FEB 19, 2020, View Source [SID1234554488]).

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Management will conduct a conference call at 5:00 PM ET on the same day to discuss Aclaris’ financial results and provide a general business update. The conference call will be webcast live over the Internet and can be accessed by logging on to the "Investors" page of the Aclaris Therapeutics website, www.aclaristx.com, prior to the event. A replay of the webcast will be archived on the Aclaris Therapeutics website for 30 days following the call.

To participate on the live call, please dial (844) 776-7782 (domestic) or (661) 378-9535 (international), and reference conference ID 9958112 prior to the start of the call.