3SBio and TLC Form Exclusive Partnership to Commercialize Two NanoX™ Products in Mainland China

On March 3, 2019 3SBio Inc. ("3SBio") (HKEX: 1530) and Taiwan Liposome Company, Ltd. ("TLC") (Nasdaq: TLC, TWO: 4152) reported an exclusive partnership to commercialize in mainland China two liposomal products utilizing TLC’s proprietary NanoX technology platform in the therapeutic areas of oncology and severe infectious diseases (Press release, 3SBio, MAR 3, 2019, View Source [SID1234553911]). Under this alliance, TLC and 3SBio will cooperate to obtain regulatory approvals in mainland China, and TLC will utilize its commercial-scale manufacturing capabilities to supply the two liposomal products for 3SBio to commercialize in mainland China. The two companies also agreed to further collaboration in researching and developing other novel liposomal products in the therapeutic areas of osteoarthritis, pain management, ophthalmology, and oncology.

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"3SBio’s partnership with TLC reflects the continuous execution of our strategy to introduce novel therapeutics which addresses significant unmet medical needs of cancer patients in China," said Dr. Jing Lou, Chairman and Chief Executive Officer of 3SBio. He added, "We intend to seek regulatory approval for the two liposomal products to treat patients with cancer and severe infectious diseases in the near future. We believe both candidates have strong commercial potential due to the lower toxicity profile of TLC’s liposomal formulations and will complement 3SBio’s oncology therapeutic and supportive care portfolio while leveraging 3SBio’s commercial platform with over 2,500 sales and marketing professionals across China."

Under the terms of the agreement, TLC is eligible to receive up to US$25 million in upfront payments for each product and subsequent regulatory and sales milestone payments. TLC is also eligible a share of the potential profits from product sales. Additional financial terms were not disclosed.

"We are excited to have 3SBio as a partner to collaborate on the advancement of our NanoX technology-based products," commented TLC President George Yeh. "This opportunity is an endorsement to the competency of our NanoX platform, which was applied to products that have been approved for sale in Taiwan. With this partnership, we are able to take full advantage of NanoX’s manufacturing capabilities to expand our commercial framework. We believe that 3SBio’s prominent position in China’s biotech industry, coupled with the commercial capacities at our contract manufacturing organizations’ facilities in Australia and Taiwan, will lead to the successful launch and commercialization of these products in mainland China."

Rakuten Aspyrian Announces Name Change to Rakuten Medical

On March 1, 2019 Rakuten Aspyrian, a biotechnology company developing precision-targeted cancer therapies based on its proprietary Photoimmunotherapy platform, reported that it has changed its name to Rakuten Medical, Inc (Press release, Rakuten Aspyrian, MAR 1, 2019, View Source/2019/02/28/rakuten-aspyrian-announces-name-change-to-rakuten-medical/" target="_blank" title="View Source/2019/02/28/rakuten-aspyrian-announces-name-change-to-rakuten-medical/" rel="nofollow">View Source [SID1234533855]). This name more closely reflects the company’s corporate purpose of creating a global biotechnology company integrating research and development with commercial operations in order to develop therapeutics that improve cancer patient outcomes.

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"We are aiming to deliver PIT platform to as many cancer patients and as early as possible worldwide. Our new name that becomes effective today, Rakuten Medical, better aligns with our goal of developing a global brand that resonates within the pharmaceutical and medical device industries," said Mickey Mikitani, chairman and CEO of Rakuten Medical. "Despite our name change, our mission of ‘Conquering cancer, For life’ will not change. We are stronger today than ever before as we continue building the organization necessary to conquer cancer by developing innovative cancer treatments."

For more information, visit View Source

Oncolytics Biotech(R) to Host Conference Call to Discuss Year End Financial Results and Operational Highlights

On March 1, 2019 Oncolytics Biotech Inc. (NASDAQ: ONCY) (TSX: ONC), currently developing pelareorep, an intravenously delivered immuno-oncolytic virus, reported that it will host a conference call and live webcast for Analysts and Institutional Investors at 8:30 a.m. ET on Friday, March 8, 2019 following release of its year end 2018 financial results (Press release, Oncolytics Biotech, MAR 1, 2019, https://ir.oncolyticsbiotech.com/news/detail/448/oncolytics-biotechr-to-host-conference-call-to-discuss-year-end-financial-results-and-operational-highlights [SID1234533905]).

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The live call may be accessed by dialing (877) 407-9205 for callers in North America. Overseas callers should contact investor relations for the toll-free dial information for their country. A replay of this call will be available approximately two hours after the call is ended at (877) 481-4010, using the replay code 44902 and will be available for one week. A live webcast of the call will be accessible on the Investor Relations page of Oncolytics’ website at www.oncolyticsbiotech.com and will be archived for three months.

MaxCyte Announces Multi-Drug Clinical & Commercial Agreement with Kite, a Gilead Company

On March 1, 2019 MaxCyte, the global cell-based medicines and life sciences company, reported that it has expanded its relationship with Kite, a Gilead Company, by entering into a multi-drug clinical and commercial agreement (Press release, MaxCyte, MAR 1, 2019, View Source [SID1234537626]). Under the terms of the agreement, Kite will use MaxCyte’s Flow Electroporation Technology to enable non-viral cell engineering for development of multiple CAR-T drug candidates for up to 10 targets.

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"We’re excited to take our relationship with Kite further into product development, providing the company the ability to leverage MaxCyte’s versatile cell engineering platform to enable the power of gene-editing for clinical and commercial development of critical new CAR-T therapeutics," said Doug Doerfler, President & CEO of MaxCyte, Inc.

The expansion of the Kite-MaxCyte relationship builds on an existing research agreement announced in November 2018. Under the terms of the new license agreement, Kite obtains non-exclusive clinical and commercial-use rights to MaxCyte’s cell engineering platform to develop CAR-T therapies, and MaxCyte will receive development and approval milestones and sales-based payments in addition to other licensing fees.

Allergan Presents Data From Seven Abstracts At The 2019 American Academy of Dermatology (AAD) in Washington D.C.

On March 1, 2019 Allergan plc (NYSE: AGN) reported that its data will be featured during the 2019 American Academy of Dermatology (AAD) Annual Meeting in Washington D.C. March 1-5, 2019 (Press release, Allergan, MAR 1, 2019, View Source [SID1234533873]).

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The meeting will be held at the Walter E. Washington Convention Center and the scheduled times (noted in local Eastern Time) for the Allergan presentations are as follows:

Oral Poster Presentations

Botulinum Neurotoxin Type A Directly Affects Sebocytes and Inhibits Induced Lipogenesis

Authors: Hui You, Alex Chernavsky, Sergei Grand, Amy Brideau-Andersen, Birgitte Jacky
Friday, 3/1: 10:00-10:05AM, Hall H, ePoster Presentation Center 1
Protective and Reparative Effects of a Topical Dual Serum System Against UV-Induced Skin Damage

Authors: Elizabeth Makino, Pricilla Tan, Rahul C. Mehta
Saturday, 3/2: 9:45-9:50AM, Hall H, ePoster Presentation Center 1
Environmental protection and rejuvenation from a novel antioxidant dual serum system: A randomized, double-blind, regimen controlled, multi-center study

Authors: Zoe D. Draelos, Elizabeth Makino, Priscilla Tan, Kuniko Kadoya, Audrey Nguyen, Lily Jiang, Rahul C. Mehta
Sunday, 3/3: 9:10-9:15AM, Hall D, ePoster Presentation Center 2
Poster Presentations

Botulinum Neurotoxin Type A Exhibits a Linear Correlation Between Dose, Peak Efficacy and Duration of Effect in Functional Assays

Authors: Greg S. Nicholson, Dave Canty, Amy D. Brideau-Andersen and Ron S. Broide
Available for online viewing during program
Safety and Efficacy of OnabotulinumtoxinA for Treatment of Masseter Muscle Hypertrophy: Results from a Phase 2 Dose-Escalation Study

Authors: Jean Carruthers, Steven Liew, Jason K Rivers, Shyi-Gen Chen, Shannon Humphrey, Elisabeth Lee, Beta Bowen, Mitchell F. Brin
Available for online viewing during program
Clinical Efficacy of a Novel Two-Part Skincare System on Pollution-Induced Skin Damage

Authors: Elizabeth T. Makino, Annie Jain, Priscilla Tan, Audrey Nguyen, Alain Mogac, Kuniko Kadoya
Available for online viewing during program
Evaluation of the Protective Effect of a Topical Serum Against Particles Modeling Atmospheric Pollution

Authors: Elizabeth Makino, Pricilla Tan, Cécile Charmel, Rahul C. Mehta
Available for online viewing during program