Oncternal Therapeutics to Report Third Quarter 2019 Financial Results and Provide Business Update

On October 31, 2019 Oncternal Therapeutics, Inc. (Nasdaq: ONCT), a clinical-stage biopharmaceutical company focused on the development of novel oncology therapies, reported that it will report third quarter 2019 financial results after the U.S. financial markets close on Thursday, November 7, 2019 (Press release, Oncternal Therapeutics, OCT 31, 2019, View Source [SID1234550136]). Oncternal’s management will host a webcast and conference call at 2:00 p.m. PST (5:00 p.m. EST) to discuss the Company’s financial results and provide a comprehensive business update.

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The live webcast of the call will be available online via a link from the investor relations page of the Company’s website at www.oncternal.com, and the call will be archived there for at least 30 days.

Bruker Reports Third Quarter 2019 Financial Results

On October 31, 2019 Bruker Corporation (Nasdaq: BRKR) reported financial results for its third quarter and for the nine months ended September 30, 2019 (Press release, Bruker, OCT 31, 2019, View Source [SID1234550152]).

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Third Quarter 2019 Financial Results

Bruker’s revenues for the third quarter of 2019 were $521.1 million, an increase of 11.7% compared to the third quarter of 2018. In the third quarter of 2019, Bruker’s year-over-year organic revenue growth was 7.6%. Growth from acquisitions was 6.4%, while foreign currency translation had a negative effect of 2.3%.

Third quarter 2019 Bruker Scientific Instruments (BSI) segment revenues of $471.8 million increased 13.1% year-over-year, including organic growth of 8.6%. Third quarter 2019 Bruker Energy & Supercon Technologies (BEST) segment revenues of $52.5 million increased 3.1% year-over-year, including an organic revenue decline of 0.8%, net of intercompany eliminations.

Third quarter 2019 GAAP operating income was $87.8 million, compared to $69.1 million in the third quarter of 2018, representing GAAP operating margins of 16.8% and 14.8%, respectively. Non-GAAP operating income was $95.5 million, compared to $83.3 million in the third quarter of 2018. Bruker’s third quarter 2019 non-GAAP operating margin of 18.3% increased 40 basis points from 17.9% in the third quarter of 2018.

Third quarter 2019 GAAP diluted earnings per share (EPS) were $0.39, compared to $0.28 in the third quarter of 2018. Non-GAAP EPS were $0.43, a 16.2% increase compared to $0.37 in the third quarter of 2018.

First Nine Months of 2019 Financial Results

For the first nine months of 2019, Bruker’s revenues were $1,472.7 million, an increase of 9.7% from $1,342.0 million in the first nine months of 2018. In the first nine months of 2019, Bruker’s organic revenue growth was 6.0% year-over-year. Growth from acquisitions was 7.0%, while foreign currency translation had a negative effect of 3.3%.

In the first nine months of 2019, BSI segment revenues of $1,331.0 million increased 10.3% year-over-year, including organic growth of 5.8%. First nine months 2019 BEST segment revenues of $152.2 million increased 9.3% year-over-year, including organic growth of 7.0%, net of intercompany eliminations.

In the first nine months of 2019, GAAP operating income was $183.2 million, compared to $156.0 million in the first nine months of 2018, representing GAAP operating margins of 12.4% and 11.6%, respectively. Non-GAAP operating income was $231.5 million, compared to $195.1 million in the first nine months of 2018. Bruker’s non-GAAP operating margin in the first nine months of 2019 was 15.7%, an increase of 120 basis points, compared to 14.5% in the first nine months of 2018.

In the first nine months of 2019, GAAP EPS were $0.82, compared to $0.65 in the first nine months of 2018. Non-GAAP EPS were $1.04, an increase of 20.9% over $0.86 in the first nine months of 2018.

A reconciliation of non-GAAP to GAAP financial measures is provided in the tables accompanying this press release.

Frank H. Laukien, President and CEO of Bruker, commented: "We are very pleased with our year-to-date progress, with 6% organic and 13% constant currency revenue growth, highlighted by our strong performance in life science mass spectrometry solutions and in microbiology. We are on track to deliver solid margin and EPS improvements in 2019, and we are increasing our non-GAAP EPS outlook for the full year."

Fiscal Year (FY) 2019 Financial Outlook

For FY 2019, Bruker continues to expect year-over-year revenue growth of 7.0% to 8.0%, which now includes the following estimates:

organic revenue growth of 4.5% to 5.5%;
growth from acquisitions of approximately 5.5%;
constant currency revenue growth of 10.0% to 11.0%; and
an increased foreign currency revenue headwind of approximately 3%.
Bruker continues to expect non-GAAP operating margin expansion in FY 2019 of 90 to 120 basis points over its FY 2018 non-GAAP operating margin of 16.8%. This now includes approximately 50 basis points of foreign currency tailwind. Bruker is raising its FY 2019 non-GAAP EPS outlook to a range between $1.59 and $1.62, representing a 13.5% to 15.5% increase compared to FY 2018.

For our outlook for FY 2019 non-GAAP operating margin and non-GAAP EPS, we are not able to provide without unreasonable effort the most directly comparable GAAP financial measures, or reconciliations to such GAAP financial measures on a forward-looking basis. Please see "Use of Non-GAAP Financial Measures" below for a description of items excluded from our expected non-GAAP operating margin and non-GAAP EPS.

Quarterly Earnings Call

Bruker will host a conference call and webcast to discuss its financial results, business outlook, and related corporate and financial matters today, October 31, at 4:30 p.m. Eastern Daylight Time. To listen to the webcast, investors can go to View Source and click on the "Q3 2019 Earnings Webcast" hyperlink. A slide presentation that will be referenced during the webcast will be posted to our Investor Relations website shortly before the webcast begins. Investors can also listen to the earnings webcast via telephone by dialing 1-888-437-2685 (US toll free) or +1-412-317-6702 (international) and referencing "Bruker’s Third Quarter 2019 Earnings Conference Call". A telephone replay of the conference call will be available by dialing 1-877-344-7529 (US toll free) or +1-412-317-0088 (international) and entering conference number: 10136323. The replay will be available beginning one hour after the end of the conference through December 1, 2019.

Syndax to Announce Third Quarter 2019 Financial Results and Host Conference Call and Webcast on November 7, 2019

On October 31, 2019 Syndax Pharmaceuticals, Inc. ("Syndax," the "Company" or "we") (Nasdaq:SNDX), a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies, reported that it will release its third quarter 2019 financial results on Thursday, November 7, after the close of the U.S. financial markets (Press release, Syndax, OCT 31, 2019, View Source [SID1234550099]).

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In connection with the earnings release, Syndax’s management team will host a conference call and live audio webcast at 4:30 p.m. ET on Thursday, November 7, to discuss the Company’s financial results and provide a general business update.

The live audio webcast and accompanying slides may be accessed through the Events & Presentations page in the Investors section of the Company’s website at www.syndax.com. Alternatively, the conference call may be accessed through the following:

Conference ID: 9065948
Domestic Dial-in Number: (855) 251-6663
International Dial-in Number: (281) 542-4259
Live webcast: View Source

For those unable to participate in the conference call or webcast, a replay will be available for 30 days on the Investors section of the Company’s website, www.syndax.com.

GlycoMimetics to Report Third Quarter 2019 Financial Results on November 7, 2019

On October 31, 2019 GlycoMimetics, Inc. (NASDAQ: GLYC) reported that it will host a conference call and webcast to report its third-quarter 2019 financial results on Thursday, November 7, 2019, at 8:30 a.m. ET (Press release, GlycoMimetics, OCT 31, 2019, View Source [SID1234550121]).

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The dial-in number for the conference call is (844) 413-7154 (U.S. and Canada) or (216) 562-0466 (international) and entering passcode 9845948. To access the live audio webcast, or the subsequent archived recording, visit the "Investors – Events & Presentations" section of the GlycoMimetics website at www.glycomimetics.com. The webcast will be recorded and available for replay on the GlycoMimetics website for 30 days following the call.

Myovant Sciences Enters Landmark Agreement with Sumitomo Dainippon Pharma to Secure Major Financial Backing and Safeguards for Minority Shareholder

On October 31, 2019 Myovant Sciences (NYSE: MYOV), a healthcare company focused on developing innovative treatments for women’s health and prostate cancer, reported that it has entered into a landmark agreement with Sumitomo Dainippon Pharma Co., Ltd. (TSE: 4506), a leading Japanese pharmaceutical company, on a $350 million low-interest, five-year term loan facility and an Investor Rights Agreement (Press release, Myovant Sciences, OCT 31, 2019, https://investors.myovant.com/news-releases/news-release-details/myovant-sciences-enters-landmark-agreement-sumitomo-dainippon [SID1234550137]). This agreement was made in conjunction with Myovant’s founding shareholder, Roivant Sciences, and Sumitomo Dainippon Pharma entering into a definitive agreement for the creation of a broad strategic alliance. At closing, the alliance entity will assume Roivant’s ownership interest in Myovant, which is expected to represent not less than a majority of Myovant’s outstanding shares.

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"Sumitomo Dainippon Pharma is committed to supporting Myovant through commercialization and profitability as the robust potential of relugolix is unlocked for women with uterine fibroids or endometriosis, and for men with prostate cancer," said Hiroshi Nomura, Representative Director, President and CEO of Sumitomo Dainippon Pharma.

"Myovant is delighted to have the support of Sumitomo Dainippon Pharma," said Lynn Seely, M.D., President and CEO of Myovant. "With total cash and committed financing of approximately $500 million, including the Sumitomo Dainippon Pharma term loan facility, we will be in a strong financial position to advance the commercialization of relugolix."

Sumitomo Dainippon Pharma has committed to provide Myovant a $350 million low-interest, five-year term loan facility, with no repayments due until the end of the term to fund Myovant’s operating expenditures. Myovant will be able to access the facility on a quarterly basis, subject to certain terms and conditions. The agreement will become effective upon close of the Sumitomo Dainippon Pharma transaction with Roivant.

Myovant and Sumitomo Dainippon Pharma will also enter into an Investor Rights Agreement, which provides that the Myovant Board of Directors will continue to include a minimum of three independent directors who will have approval rights over certain corporate actions, including related-party transactions between Myovant and Sumitomo Dainippon Pharma. The ratio of independent to non-independent directors is also expected to remain unchanged. The Investor Rights Agreement will further include standstill provisions including a non-waivable condition requiring approval by a majority of the minority shareholders for any transaction that would cause Sumitomo Dainippon Pharma to hold beneficial ownership of Myovant of greater than 60%. Additionally, for a standstill period of three years, any such transaction must also be made on a confidential basis to the independent directors and is subject to approval by a majority of the independent directors.

Subject to the closing of the strategic alliance transaction, Sumitomo Dainippon Pharma has also agreed that upon Myovant’s request, the parties will discuss terms upon which Sumitomo Dainippon Pharma will provide Myovant access to its U.S. commercial infrastructure and operational support as Myovant moves forward with the commercialization of relugolix.

Earlier this year, Myovant announced positive topline data from two Phase 3 studies, LIBERTY 1 and LIBERTY 2, evaluating relugolix combination therapy in women with uterine fibroids, as well as positive results from a separate bioequivalence study supporting a potential one pill, once-a-day dosing regimen of relugolix combination therapy. Myovant expects to announce topline results from its Phase 3 study, HERO, evaluating relugolix monotherapy in men with advanced prostate cancer later this year and results from two Phase 3 studies, SPIRIT 1 and SPIRIT 2, evaluating relugolix combination therapy in women with endometriosis in the first and second quarters of 2020.