On April 9, 2019 Cytonus Therapeutics Inc., a biotechnology company developing new platforms for delivering biologics, reported that it will be presenting preclinical data for its Cargocyte technology platform at the American Society of Gene and Cell Therapy (ASGCT) (Free ASGCT Whitepaper) annual meeting April 29 – May 2 in Washington, DC (Press release, Cytonus Therapeutics, APR 9, 2019, View Source [SID1234535083]).

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"We are excited to be presenting our preclinical data supporting Cargocytes, a first-of-its-kind, cell-based platform technology for delivery of an Oncolytic Virus into metastatic tumors," said Remo Moomiaie-Qajar, M.D., president and CEO of Cytonus. "Our technology unleashes the promise of using Oncolytic Viruses to treat solid tumors by addressing a number of critical problems they inherently have, mainly homing the viruses to specific tissue without the immune system destroying it and then delivering those viruses into tumor cells. In addition, we are proud of our growing immune-oncology work with our Cargocytes and look forward to sharing our data at this year’s ASGCT (Free ASGCT Whitepaper) meeting."

Cargocytes are engineered allogenic cell lines that can carry a variety of payloads like small molecule compounds, gene editing therapies, therapeutic RNAs, and powerful biologics such as immune modulating cytokines, antibodies and oncolytic viruses.

Details of the presentations:

Abstract Title: Cargocyte Biofactories: A New Versatile Cell Therapy Platform for Delivery of a Wide Range of Biologics

Session Date/Time: Monday Apr 29, 2019 5:00 PM – 6:00 PM
Session title: Cancer-Targeted Gene & Cell Therapy
Room: Columbia Hall
Final abstract number: 272

Abstract Title: Cargocyte Biofactories: A Novel Platform for Delivering Oncolytic Viruses to Treat Metastatic Cancer

Session Date/Time: Tuesday Apr 30, 2019 3:30 PM – 5:15 PM
Session title: Oncolytic Viruses II
Room: International Ballroom
Our Presentation Time: 4:00 PM – 4:15 PM
Final abstract number: 404

Abstract Title: Cargocytes: A Novel Cell Therapy Platform to Drive Anti-Tumor Immunity

Session Date/Time: Tuesday Apr 30, 2019 5:00 PM – 6:00 PM
Session title: Cancer-Immunotherapy, Cancer Vaccines
Room: Columbia Hall
Final abstract number: 578

Cytonus will also be presenting at the Bio International Convention, June 3-6, 2019 in Philadelphia.

On April 9, 2019 Syros Pharmaceuticals (NASDAQ: SYRS), a leader in the development of medicines that control the expression of genes, reported the closing of its previously announced concurrent underwritten public offerings of (i) 8,667,333 shares of its common stock and accompanying Class A warrants to purchase up to 1,951,844 shares of its common stock, at a combined price to the public of $7.50 per common share and accompanying Class A warrant and (ii) 666 shares of its Series A convertible preferred stock, which are convertible into 666,000 shares of its common stock, and accompanying Class A warrants to purchase up to 166,500 shares of its common stock, at a combined price to the public of $7,500 per Series A share and accompanying Class A warrant (Press release, Syros Pharmaceuticals, APR 9, 2019, View Source [SID1234535084]). Each Class A warrant has an exercise price of $8.625 per share and expires 3.5 years from the date of issuance. Gross proceeds from the offerings, before deducting underwriting discounts and commissions and offering expenses, were approximately $70 million.

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Cowen and Piper Jaffray & Co. acted as joint book-running managers for the offerings. JMP Securities acted as lead manager and Roth Capital Partners acted as co-manager.

The securities were offered by Syros pursuant to a shelf registration statement that was filed with the Securities and Exchange Commission ("SEC") on July 20, 2017 and declared effective by the SEC on July 31, 2017. Final prospectus supplements and accompanying prospectuses relating to, and describing the terms of, each offering were filed with the SEC and are available on the SEC’s website at www.sec.gov. Copies of the prospectus supplements and the accompanying prospectuses relating to each offering can be obtained from Cowen and Company, LLC, c/o Broadridge Financial Services, 1155 Long Island Avenue, Edgewood, NY 11717, Attention: Prospectus Department, or by telephone at (631) 274-2806; or Piper Jaffray & Co., Attention: Prospectus Department, 800 Nicollet Mall, J12S03, Minneapolis, MN 55402, or by telephone: 800-747-3924, or by email: [email protected].

This press release does not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

On April 9, 2019 Horizon Pharma plc (Nasdaq: HZNP) reported that its first-quarter 2019 financial results will be released on Wednesday, May 8, 2019. Following the announcement, Horizon’s management will host a live webcast at 8 a.m. Eastern Time to review the Company’s financial and operating results (Press release, Horizon Pharma, APR 9, 2019, View Source [SID1234535313]).

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The live webcast and replay may be accessed at View Source Please connect to the Company’s website at least 15 minutes before the live webcast to ensure adequate time for any software download that may be needed to access the webcast.

On April 9, 2019 Illumina, Inc. (NASDAQ:ILMN) reported that it will issue results for first quarter 2019 following the close of market on Thursday, April 25, 2019 (Press release, Illumina, APR 9, 2019, View Source [SID1234535085]).

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On the same day, at 2:00 pm Pacific Time (5:00 pm Eastern Time) Francis deSouza, President and Chief Executive Officer, and Sam Samad, Senior Vice President and Chief Financial Officer, will host a conference call with analysts, investors, and other interested parties to discuss financial and operating results.

Conference Call Details

The conference call will begin at 2:00 pm Pacific Time (5:00 pm Eastern Time) on Thursday, April 25, 2019. Interested parties may access the live teleconference through the Investor Relations section of Illumina’s website under the "company" tab at www.illumina.com. Alternatively, individuals can access the call by dialing 1 (844) 647-5490 or 1 (615) 247-0295 outside North America, both with conference ID 9153579.

A replay of the conference call will be posted on Illumina’s website after the event and will be available for at least 30 days following.

On April 9, 2019 Bio-Techne Corporation (NASDAQ:TECH) reported that management will host a conference call on Tuesday, April 30, 2019 at 8:00 a.m. CDT to review third quarter 2019 financial results (Press release, Bio-Techne, APR 9, 2019, https://investors.bio-techne.com/news/detail/133/bio-techne-to-host-conference-call-on-april-30-2019-to-announce-third-quarter-2019-financial-results [SID1234536923]).

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Access to the discussion may be obtained as follows:

Time:

8:00 a.m. CDT

Date:

April 30, 2019

Dial-in:

1-866-548-4713 or 1-323-794-2093 (for international callers)

Conference ID:

9482573

A recorded rebroadcast will be available for interested parties unable to participate in the live conference call. To access the recording, U.S. callers should dial 1-844-512-2921 or international callers should dial 1-412-317-6671 and enter the replay access code 9482573. The recording can also be accessed by going to:

View Source

The replay will be available from 11:00 a.m. CDT on Tuesday, April 30, 2019 until 11:00 p.m. CDT on Thursday, May 30, 2019.