On April 29, 2019 Eagle Pharmaceuticals, Inc. ("Eagle" or the "Company") (Nasdaq: EGRX) reported that the Company will release its 2019 first quarter financial results on Tuesday, May 7, 2019, before the market opens (Press release, Eagle Pharmaceuticals, APR 29, 2019, View Source [SID1234535549]).

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Scott Tarriff, Chief Executive Officer, and Pete Meyers, Chief Financial Officer, will host a conference call to discuss the results as follows:

Date Tuesday, May 7, 2019
Time
8:30 a.m. EDT

Toll free (U.S.) 877-876-9176
International 785-424-1670
Webcast (live and replay)
www.eagleus.com, under the "Investor Relations" section

A replay of the conference call will be available for one week after the call’s completion by dialing 800-839-5493 (US) or 402-220-2552 (International) and entering conference call ID EGRXQ119. The webcast will be archived for 30 days at the aforementioned URL.

On April 29, 2019 Nicox SA (Euronext Paris: FR0013018124, COX), an international ophthalmology company, reported that it will be presenting at the following pharmaceutical industry and financial events in Q2 2019 (Press release, NicOx, APR 29, 2019, View Source [SID1234535676]):

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Michele Garufi, Chairman and CEO, will present at the 2019 Ophthalmology Innovation Summit (OIS) on May 2, 2019, prior to the 2019 American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting. The conference is being held at the Hilton San Diego Bayfront in San Diego, U.S.
Gavin Spencer, Chief Business Officer, will present at the JMP Securities Life Sciences Conference on June 20, 2019 to be held at the St. Regis hotel in New York, U.S.
Emmet Purtill, Senior Director of Business Development, will present at the BIO 2019 International Convention to be held from June 3-6, 2019 in Philadelphia, U.S.

The presentations will be available on the Nicox website (www.nicox.com) in the "Presentations & Events" section.

Nicox management will also participate in the following events for 1:1 meetings with investors:

May 16: European MidCap Event, Copenhagen, Denmark
June 18-19: European MidCap Event, Paris, France
June 24-25: HealthTech Investor Day, Paris, France

On April 28, 2019 Sinovant Sciences reported that its Clinical Trial Application (CTA) for derazantinib has been accepted by the Center for Drug Evaluation at the China National Medical Products Administration (NMPA), enabling the initiation of a registrational clinical trial in patients with second-line intrahepatic cholangiocarcinoma (iCCA) in the second half of 2019 (Press release, Sinovant Sciences, APR 28, 2019, View Source [SID1234535434]).

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"iCCA is one of the greatest unmet needs in oncology, particularly in China," said Dr. Rae Yuan, President of Sinovant. "Patients in the second-line setting are poorly served by existing treatment options, none of which meaningfully extend survival or reduce disease burden. Derazantinib has the potential to be the first approved treatment in China for this devastating disease state, and we look forward to begin enrolling patients in our registrational program later this year."

Derazantinib is an oral pan-FGFR (fibroblast growth factor receptor) inhibitor being developed as a potential treatment for iCCA and other tumor types with high rates of FGFR mutation. The People’s Republic of China has one of the world’s highest incidence rates of iCCA.

"We are very pleased by the approval of this CTA, which brings Sinovant a step closer to delivering derazantinib to Chinese patients," said Dr. Xinan Chen, Executive Chairman of Sinovant. "Sinovant’s advancement of derazantinib for patients with iCCA underscores our commitment to addressing major public health priorities in China."

About Derazantinib

Derazantinib is a potent, orally administered inhibitor of the fibroblast growth factor receptor (FGFR) family, a key driver of cell proliferation, differentiation, and migration. In a Phase 1/2 study in patients with iCCA harboring FGFR2 gene fusions, treatment with derazantinib resulted in an objective response rate of 21%, nearly 3 times higher than standard-of-care chemotherapy. Sinovant’s partner Basilea is conducting a similar global registrational study of derazantinib in American and European patients with FGFR2 fusion-positive second-line iCCA. More information on that program is available here.

About Intrahepatic Cholangiocarcinoma

Cholangiocarcinoma (CCA) is the most common biliary malignancy and the second most common malignancy in the liver after hepatocellular carcinoma (HCC).1 Depending on the anatomic location, CCA is classified as intrahepatic (iCCA), perihilar (pCCA), and extrahepatic (eCCA). iCCA originates from the intrahepatic biliary ductal system and forms an intrahepatic mass. iCCA is an aggressive cancer, with a median 5-year survival rate of only 15% for patients diagnosed with early-stage disease.2 Reports show that in China’s most populous cities the incidence of cholangiocarcinoma is more than 7 cases per 100,000 people, and a majority of cases are intrahepatic.3

On April 26, 2019 Global pharmaceutical company Mylan N.V. (NASDAQ: MYL) reported that it will release its first quarter 2019 financial results on Tues., May 7, before the open of the U.S. financial markets (Press release, Mylan, APR 26, 2019, View Source [SID1234535425]). The company also will host a webcast at 10 a.m. ET on May 7, to discuss the results.

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The briefing can be accessed live by calling 855.493.3607 or 346.354.0950 for international callers (ID#: 4992316) or at the following address on the company’s website: investor.mylan.com. A replay of the webcast also will be available on the website.

Mylan is a global pharmaceutical company committed to setting new standards in healthcare. Working together around the world to provide 7 billion people access to high quality medicine, we innovate to satisfy unmet needs; make reliability and service excellence a habit; do what’s right, not what’s easy; and impact the future through passionate global leadership. We offer a growing portfolio of more than 7,500 marketed products around the world, including antiretroviral therapies on which more than 40% of people being treated for HIV/AIDS globally depend. We market our products in more than 165 countries and territories. We are one of the world’s largest producers of active pharmaceutical ingredients. Every member of our approximately 35,000-strong workforce is dedicated to creating better health for a better world, one person at a time. Learn more at Mylan.com. We routinely post information that may be important to investors on our website at investor.mylan.com.

On April 26, 2019 PharmaMar (MSE:PHM) has reported an agreement with Hong Kong listed Luye Pharma Group Ltd. (HKG:2186) to develop and commercialize the marine-inspired anti-tumor compound, lurbinectedin (Zepsyre) in Small Cell Lung Cancer (SCLC), and potentially in other indications in China, Hong Kong and Macao (Press release, PharmaMar, APR 26, 2019, View Source [SID1234535426]).

Under the terms of this agreement, PharmaMar will receive an up-front payment of US $5 million followed by additional payments for regulatory and sales milestones, as well as double-digit royalties. This income may be increased if other therapeutic indications are approved.

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Luye Pharma will commit to develop lurbinectedin in SCLC in China, while PharmaMar will retain exclusive production rights for the compound.

José María Fernández Sousa-Faro, PhD, President of PharmaMar, commented, "PharmaMar is delighted to team-up with Luye Pharma Group Ltd. for China, a leader in the above mentioned space with an outstanding track record in Oncology, that has successfully brought innovative cancer medicines to Chinese patients."

Rongbing Yang, President of Luye Pharma Group Ltd., said about this new licensing deal: "This agreement with PharmaMar enables us to address the treatment of this type of disease in China, which is much more widespread than in the US and Europe.Oncology is one of the core therapeutic areas for Luye Pharma’s long-term development. We will continue to increase investment to further enrich our oncology pipelines and enhance our competitiveness in this field of treatment, through external partnerships with more innovative companies such as PharmaMar and also through our in-house R&D innovation".

2 According to data from the World Health Organization (WHO), China has the highest number of cancer cases in the world, due to population ageing, tobacco and pollution. China is also the country with the highest mortality rate in Asia for lung cancer. This type of tumor affects a larger number of people than in the U.S., Europe and Japan combined. The WHO estimates that by 2020, 800,000 new cases of lung cancer will be diagnosed and will cause nearly 700,000 deaths. It is estimated that SCLC represents approximately 18% of all lung cancers in China.

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