NewLink Genetics Announces Presentation of Abstracts at AACR Annual Meeting

On March 14, 2018 NewLink Genetics Corporation (NASDAQ: NLNK) reported that two abstracts pertaining to the company’s indoximod program will be presented at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) 2018 Annual Meeting in Chicago (Press release, NewLink Genetics, MAR 14, 2018, View Source [SID1234524773]).

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Clinical Trials Plenary Session: Abstract 10973 – Front-line therapy of DIPG using the IDO pathway inhibitor indoximod in combination with radiation and chemotherapy, to be presented during the "Multimodality Immuno-oncology Approaches" session, Sunday, April 15, 2018, 12:45 PM – 2:45 PM CT

Poster Session: Abstract 3753 – Indoximod modulates AhR-driven transcription of genes that control immune function, to be presented during poster session PO.IM02.07, April 17, 2018, 8:00 AM – 12:00 PM CT

The complete text of Clinical Plenary Session abstracts that have not been selected for the press program will be posted to the AACR (Free AACR Whitepaper) website on Friday, April 13. The text of clinical trials abstracts that have been selected for inclusion in the press program will not be posted online until the date and time of presentation.
"We are pleased to have been chosen to present these abstracts at the upcoming AACR (Free AACR Whitepaper) meeting," said Charles J. Link, Jr, MD, Chairman, CEO and Chief Scientific Officer. "Encouraging early clinical data of indoximod plus radiation for pediatric patients with DIPG, a rare and lethal form of brain cancer, will be presented. In addition, our data further clarifying indoximod’s differentiated mechanism of action will also be presented."
About Indoximod
Indoximod is an investigational, orally available small molecule targeting the IDO pathway. The IDO pathway is a key immuno-oncology target involved in regulating the tumor microenvironment and immune escape. Indoximod is being evaluated in combination with treatment regimens including anti-PD-1/PD-L1 agents, cancer vaccines, and chemotherapy across multiple indications such as melanoma, pancreatic cancer and other malignancies.

Heat Biologics to Present at the B. Riley FBR Inaugural China Healthcare Investing & Partnering Symposium

On March 14, 2018 Heat Biologics, Inc. ("Heat") (NASDAQ: HTBX), a biopharmaceutical company developing drugs designed to activate a patient’s immune system against cancer, reported that Dr. John Prendergast, Lead Independent Director of Heat Biologics, will present corporate highlights and positive interim data from its Phase 2 lung cancer clinical trial for advanced non-small cell lung cancer, in combination with Bristol-Myers Squibb’s checkpoint inhibitor nivolumab (Opdivo) at the B. Riley FBR Inaugural China Healthcare Investing & Partnering Symposium (CHIPS) on Friday, March 16, 2018 at 10AM China Standard Time (Press release, Heat Biologics, MAR 14, 2018, View Source [SID1234524970]). The conference will be held March 15-17, 2018 at the Intercontinental Hotel in Hangzhou, China. CHIPS is focused on building cross-border relationships between Chinese and Western Healthcare investors and companies.

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Heat Biologics’ presentation will not be webcast, but a copy may be found in the Investor Relations section of the Company’s website.

10-K – Annual report [Section 13 and 15(d), not S-K Item 405]

Intellia Therapeutics has filed a 10-K – Annual report [Section 13 and 15(d), not S-K Item 405] with the U.S. Securities and Exchange Commission (Filing, 10-K, Intellia Therapeutics, 2018, MAR 14, 2018, View Source [SID1234524760]).

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MEI Pharma To Present at Two Upcoming Investor Conferences

On March 14, 2018 MEI Pharma, Inc. (NASDAQ: MEIP), an oncology company focused on the clinical development of novel therapies for cancer, reported that it will webcast a business overview and update by Daniel P. Gold, Ph.D., president and chief executive officer, at each of the following upcoming healthcare conferences (Press release, MEI Pharma, MAR 14, 2018, View Source [SID1234524761]):

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The Oppenheimer 28th Annual Healthcare Conference at 10:55 a.m. ET on Wednesday, March 21, 2018 in New York, NY.
The 17th Annual Needham Healthcare Conference at 4:30 p.m. ET on Tuesday, March 27, 2018 in New York, NY.

A live audio webcast of each event can be accessed on the Events & Presentations page of the Investors section of MEI Pharma’s website at View Source, or by following the links below in your web browser.

Oppenheimer 28th Annual Healthcare Conference: https://veracast.com/webcasts/opco/healthcare2018/07207656259.cfm
17th Annual Needham Healthcare Conference: View Source

An archived replay of each webcast will be available on MEI Pharma’s website for at least 30 days after the live event concludes.

Quanterix Corporation Releases Operating Results for Fourth Quarter and Fiscal Year 2017

On March 14, 2018 Quanterix Corporation (NASDAQ:QTRX), a company digitizing biomarker analysis to advance the science of precision health, reported financial results for the fourth quarter and full year of 2017 (Press release, Quanterix, MAR 14, 2018, View Source [SID1234524774]). Revenues for full year 2017 of $22.9M were at the high end of the range of $22.5-$22.9M, which was previously announced in January 2018.

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"2017 was an important year for Quanterix, and I am pleased to report progress on a number of pivotal focus areas,"said Chief Executive Officer, President and Chairman, Kevin Hrusovsky. "In our first quarter as a public company, we continued to grow revenues, scale the company for future success and make inroads launching digital biomarker technologies into neurology, oncology and infectious disease application areas."

Fourth Quarter Financial Highlights

Key financial results for the fourth quarter are shown below:

·Q4 revenue of $6.6M versus prior year Q4 of $6.7M, a decrease of 1%. Q4 2016 includes $1.8M in non-recurring revenue recognized in connection with a license; excluding that the revenue growth was 35%.

Q4 product revenue totaled $4.1M versus prior year of $3.2M; Consumables drove this performance. Product revenue included the sale of five of the newly launched SR-X benchtop reader. This launch was more than a quarter ahead of schedule.

·Q4 Service and Other Revenue totaled $2.3M versus prior year of $1.7M, an increase of 34%.

·Strong liquidity position at year-end with $79.7M of cash and $9.4M of debt.

Successfully closed its initial public offering of 4,916,480 shares of common stock at a public offering price of $15.00 per share, and received $73.7M in gross proceeds from the offering, prior to deducting underwriting discounts and commissions, and offering expenses payable by the company. The shares began trading on The NASDAQ Global Market on December 7, 2017 under the ticker symbol "QTRX."

Expanded market opportunity through the launch of the new SR-X Ultra-Sensitive Biomarker Detection System, opening the door for researchers to access ultra-sensitive protein and nucleic acid detection capabilities in a more compact and affordable system. The SR-X was made commercially available in December 2017 and Quanterix received 16 orders for the new system in Q4, with limited marketing support behind the new launch.

2017 and Recent Business Highlights

Full year 2017 revenue of $22.9M, the high end of the previously provided guidance of $22.5-22.9M, versus full year 2016 revenue of $17.6M, an increase of 30% year-over-year; excluding the 2016 non-recurring revenue recognized in connection with a license, revenue growth was 45%.

Impressive full year revenue performance in consumables (70% increase) and Accelerator (57% increase); Accelerator also carried forward significant backlog into 2018.

Reinforced leadership position in the market through presentations from Kevin Hrusovsky, Chief Executive Officer, President and Chairman, at The Leerink Partners 7th Annual Global Healthcare Conference, The 36th Annual J.P. Morgan Healthcare Conference, Innovate

Conference 2017, World Medical Innovation Forum, Second Annual Brain Trust: Pathways to Innovation, 2nd Annual Powering Precision Health Summit, and participating in the Fourth and Fifth Annual Super Bowl Brain Health Summits.

Expanded the Second Annual Powering Precision Health Summit across Neurology, Oncology and Infectious Disease application areas. The summit was impactful with over 50 presentations from speakers credited with over 6000 peer reviewed publications. The conference attracted over 500 attendees from around the world, and helped to underscore the importance of Quanterix’ technologies toward enabling personalized medicine and precision health.

Expanded multiplexing immunoassay menu and accelerated entry into pharmaceutical services with a Clinical Laboratory Improvement Amendments (CLIA) certified laboratory through the January 2018 acquisition of Aushon BioSystems, an innovator in protein detection solutions. The Company now has access to the services of the Laboratory Director of Aushon’s CLIA certified laboratory.

Strengthened its management team with the recent appointments of Dr. Dawn Mattoon as SVP of Strategic Marketing and Assay Technologies, who will lead marketing efforts for Quanterix and oversee assay development and kit manufacturing, two areas of critical importance to Quanterix’ rapidly growing customer base; and Yvan Sergeant as VP of European Commercial Operations, who will be responsible for expanding Quanterix’ business operations in Europe, and help in the establishment of a European-based Accelerator lab. The Company also expanded its relationship with neurology industry leader, Dr. Andreas Jeromin, who will serve as Scientific and Medical Advisor.

Conference Call

In conjunction with this announcement, Quanterix Corporation will host a conference call on March 14, 2018, at 4:30pm EDT to discuss the Company’s financial results and business outlook. To access this call, dial (833) 686-9351 for domestic callers, or (612) 979-9890 for international callers. Please reference the following password: 5079049.