Oncologie Launches with 16.5M USD Seed Funding Led by Pivotal bioVenture Partners China

On June 7, 2018 Oncologie, an innovative biopharmaceutical company, reported that it is launching operations in both Boston and Shanghai with $16.5M seed financing led by Pivotal bioVenture Partners China (Press release, Oncologie, JUN 7, 2018, View Source [SID1234527232]). Oncologie is committed to developing impactful cancer therapies to improve long-term survival of cancer patients worldwide. Building a pipeline of First and Best-in-Class clinical stage drug candidates through licensing and partnering, Oncologie is leveraging the recent regulatory changes in China to conduct parallel clinical development in China and the US to bring the next wave of Immuno-Oncology products to the two most important markets simultaneously.

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Oncologie is developing multiple global programs currently in Phase 2 and Phase 3 whose mechanisms are designed to combine with immune checkpoint inhibitors to improve survival benefits. The management team of Oncologie includes industry veterans from biotech and pharma with proven track records in developing innovative cancer drugs in both China and the US.

Founder, President, and CEO, Dr. Laura Benjamin said, "Oncologie has built an all-star team of creative drug developers committed to revealing the full potential of our exciting pipeline that is positioned to maximize the benefits cancer immune therapy can bring. Oncologie has created a global leading clinical pipeline since its inception earlier of this year. We look forward to working together with our partners to bring safe and effective cancer therapies to the market."

"Oncologie is leveraging the opportunity to run clinical trials in both the US and China to develop drugs for the global market," said Jimmy Wei, PhD, managing partner of the Pivotal bioVenture Partners China Fund. "We think these coordinated efforts will shorten the time between launching innovative drugs in the US and China. Since there are too many undifferentiated PD-1/PD-L1 programs in China with very few combination trials ongoing, Oncologie has positioned itself as the leader in immune combination therapies."

"We are very glad to have the opportunity to work with Dr. Benjamin to build this company," said Peter Bisgaard, managing director of Nan Fung Life Sciences. "Laura brings with her 20 years of experience as a researcher at Harvard Medical School as well as an executive in the industry, and she has built an outstanding team of experts."

Oncologie raised 16.5M USD in a seed round recently. The round was led by Pivotal bioVenture Partners China Fund and joined by Nan Fung Life Sciences, China Merchant Bank Investments and Volcanics Ventures.

Iovance Biotherapeutics Announces First Patient Dosed in Europe for Ongoing C-144-01 Phase 2 Trials in Metastatic Melanoma

On June 7, 2018 Iovance Biotherapeutics, Inc. (NASDAQ:IOVA), a biotechnology company developing novel cancer immunotherapies based on tumor infiltrating lymphocyte (TIL) technology, reported that the first patient was dosed in the ongoing C-144-01 Phase 2 trial of LN-144 (lifileucel) for the treatment of patients with metastatic melanoma at a clinical trial site in the United Kingdom (Press release, Iovance Biotherapeutics, JUN 7, 2018, View Source;p=RssLanding&cat=news&id=2353696 [SID1234527218]).

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"The dosing of the first patient with lifileucel in Europe for the treatment of metastatic melanoma marks an important milestone for Iovance and our global development plans as our European Union (EU) manufacturing is now able to support enrollment in that region," said Dr. Maria Fardis, PhD, MBA, president and chief executive officer of Iovance Biotherapeutics. "This is a major step forward and we are excited by the opportunity to offer more patients TIL therapy around the world."

In December 2017, the company announced that the Generation 2 manufacturing process, with a duration of 22 days, was selected and all studies were shifted to utilize that method of manufacturing. The company has manufacturing capability in both the US and EU. This is the first patient treated with TIL developed in an EU-based manufacturing facility.

C-144-01 is a Phase 2 multicenter study evaluating the safety and efficacy of autologous tumor infiltrating lymphocytes (lifileucel), Iovance’s lead product candidate for treatment of patients with metastatic melanoma. The study is currently enrolling in the United States and Europe. To date, Iovance has over 25 active clinical sites in the United States and Europe. The sample size for enrollment was increased to 85 for this study. Additional information on this study is available at www.clinicaltrials.gov using the identifier number NCT02360579.

Iovance Biotherapeutics, Inc., Corporate Presentation – June 2018.

On June 7, 2018 Iovance Biotherapeutics, Inc. (the "Company") presented the presentations at healthcare conferences (Press release, Iovance Biotherapeutics, JUN 7, 2018, View Source [SID1234527233]).

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Radius Health to Present at the Goldman Sachs 39th Annual Global Healthcare Conference

On June 7, 2018 Radius Health, Inc. (Nasdaq:RDUS) reported that Jesper Høiland, President and Chief Executive Officer and Pepe Carmona, Senior Vice President and Chief Financial Officer of the Company, will present a corporate update at the at the Goldman Sachs 39th Annual Global Healthcare Conference on Tuesday, June 12, 2018 (Press release, Radius, JUN 7, 2018, View Source [SID1234527219]).

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Information on the presentation is as follows:

Event: Goldman Sachs 39th Annual Global Healthcare Conference
Date: Tuesday, June 12, 2018
Time: 10:40 a.m. PDT
Location: Terranea Resort, Rancho Palos Verdes, CA
A live webcast of the presentation will be available by visiting the Investors section of Radius’ website at View Source A replay of the webcast will be archived on Radius’ website for 30 days following the presentation.

Corporate Presentation current as of June 7, 2018

On June 7, 2018 Karyopharm Therapeutics Inc presented the Corporate Presentation is current as of June 7, 2018 (Presentation, Karyopharm, JUN 7, 2018, View Source [SID1234527234]).

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