Xenetic Biosciences Announces Ticker Symbol Change to XBIO

On February 14, 2014 Xenetic Biosciences, Inc. (OTCBB:XBIO), a biopharmaceutical company focused on developing next-generation biologic drugs and novel oncology therapeutics, reported that its common stock has commenced trading under new ticker symbol "XBIO" on the OTC Bulletin Board (OTCBB). Since changing its name in January, the Company has traded on the OTCBB under the ticker symbol "GAIFD (Press release, Xenetic Biosciences, FEB 14, 2014, View Source [SID1234537822])."

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Scott Maguire, CEO of Xenetic said, "We are pleased with our new ticker, which is more shareholder friendly and better represents Xenetic. This new XBIO ticker, together with our recent announcements regarding the appointment to our Board of Directors of Dr. Tim Coté, the former Director of the U.S. Food and Drug Administration Office of Orphan Products Development, and our recent agreement with Baxter Healthcare SA, which included an upfront $10 million equity investment and $100 million in potential future cash milestones, represent a major step toward making Xenetic a significant drug development player in the U.S. markets."

Xenetic currently has a total of 146,740,691 shares of common stock issued and outstanding, taking into account the Baxter investment in January, which resulted in the issuance of an additional 10,695,187 shares of common stock.

(Press release, Selvita, FEB 11, 2014, View Source [SID:1234504702])

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20-F – Annual and transition report of foreign private issuers [Sections 13 or 15(d)]

Teva terminated the development of Obatoclax in 2013 (Filing 20-F, Teva, FEB 10, 2014, View Source [SID:1234500812])

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(Press release, Regulus, FEB 5, 2014, View Source [SID:1234503642])

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Pfizer And Merck To Collaborate On Innovative Anti-Cancer Combination Studies

On February 5, 2014 Pfizer reported that it has agreed with Merck & Co to explore the therapeutic potential of Merck’s investigational anti-PD-1 therapy, MK-3475, in combination with two Pfizer oncology assets (Press release , FEB 5, 2014, View Source [SID:1234500283]). A Phase I/II clinical study will evaluate the safety and anti-cancer efficacy of MK-3475 combined with Pfizer’s axitinib. A separate Phase I study will evaluate the safety and tolerability of the combination of MK-3475 and PF-05082566 (PF-2566).
Pfizer will conduct the clinical studies of MK-3475 plus axitinib and MK-3475 plus PF-2566. This agreement does not provide for any collaboration between Pfizer and Merck following the completion of the specified studies.
Financial terms were not disclosed.
Under a separate agreement Pfizer and Merck are currently exploring the pre-clinical combination of MK-3475 with Pfizer’s investigational therapy palbociclib (PD-0332991). Merck is conducting these pre-clinical studies. Further studies would depend on the outcome of the ongoing pre-clinical studies as well as subsequent agreement by Merck and Pfizer.

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