AVEO Announces $17 Million Private Placement

On May 13, 2016 AVEO Oncology (NASDAQ:AVEO) treported that it entered into a securities purchase agreement for a private placement with a select group of qualified institutional buyers, institutional accredited investors and accredited investors (Press release, AVEO, MAY 13, 2016, View Source;p=RssLanding&cat=news&id=2168251 [SID:1234512359]).

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The private placement will consist of 17,642,482 units, at a price of $0.965 per unit, for gross proceeds of approximately $17 million, before deducting placement agent fees and estimated offering expenses. Each unit consists of one share of AVEO’s common stock and a warrant to purchase one share of AVEO’s common stock. The warrants will have an exercise price of $1.00 per share and will be exercisable for a period of five years from the date of issuance. The closing of the financing is expected to take place on or about May 18, 2016, and is subject to standard closing conditions. AVEO expects to use the proceeds from the financing to fund its U.S. pivotal Phase 3 trial of tivozanib, to support a combination trial of tivozanib with a PD-1 inhibitor and for general corporate purposes.

The securities to be sold in this private placement have not been registered under the Securities Act of 1933, as amended (the "Securities Act"), or applicable state securities laws, and accordingly may not be offered or sold in the United States except pursuant to an effective registration statement or an applicable exemption from the registration requirements of the Securities Act and such applicable state securities laws. AVEO has agreed to file a registration statement with the Securities and Exchange Commission (the "SEC") registering the resale of the shares of common stock, and the shares of common stock issuable upon the exercise of the warrants, issued in this private placement.

This press release does not constitute an offer to sell or the solicitation of an offer to buy the securities, nor shall there be any sale of the securities in any state in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of such state. Any offering of the securities under the resale registration statement will only be by means of a prospectus.

10-Q – Quarterly report [Sections 13 or 15(d)]

XBiotech has filed a 10-Q – Quarterly report [Sections 13 or 15(d)] with the U.S. Securities and Exchange Commission (Filing, 10-Q, XBiotech, 2017, MAY 13, 2016, View Source [SID1234521614]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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“Team Chugai” to Take Part in “Relay for Life Japan” Using “3D Adventure Experience (Lung Cancer)” to promote awareness of the early detection and treatment

On May 13, 2016 Chugai Pharmaceutical Co., Ltd. (TOKYO: 4519) reported that its co-sponsorship of "Relay for Life Japan" (Organizer: Japan Cancer Society etc.), a charity activity aiming to support cancer patients and their families, and encourage the entire community to confront and conquer cancer throughout the year (Press release, Chugai, MAY 13, 2016, View Sourcenews/detail/20160513150001.html" target="_blank" title="View Sourcenews/detail/20160513150001.html" rel="nofollow">View Source [SID:1234512340]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Starting with Wakayama, Chugai will also display a virtual reality "3D Adventure Experience (Lung Cancer)" aiming to raise public awareness of lung cancer as below. Having visitors participate in "3D Adventure Experience (Lung Cancer)", Chugai appeals the importance of early detection and treatment for lung cancer.

May 14-15: "Relay for Life Japan 2016 in Wakayama (venue: Sunano-maru Square, Wakayama Park)
May 21-22: "Relay for Life Japan 2016 in Ibaraki" (venue: Kenkyu-Gakuen Station Park)
Visitors are able to try "3D Adventure Experience (Lung Cancer)" at the above-mentioned venues. Other venues where visitors can try "3D Adventure Experience (Lung Cancer)", will be sequentially announced at Chugai’s website, "Information from Chugai," (View Source).

Since 2007, Chugai has joined the Relay for Life Japan for 10 years, and has been engaged in the activities to enhance public awareness of cancer. For three years beginning in 2010, a huge balloon art in the shape of a colon, named "Giant Colon," was installed at the venues. Walking inside the tunnel-like balloon art, visitors looked at models and information panels of the internal organs, and became familiar with, and increased their understanding for colon cancer. In 2013 and 2014, visitors had the chance to learn lung cancer through quiz on lung cancer, using the iPad.

Last year, Chugai presented "3D Adventure Experience" where visitors could learn the importance of breast cancer screening. This year, Chugai will continuously offer an event focusing lung cancer to raise awareness of the importance of early detection. We will also hand out brochures for patients (Japanese only) so that visitors can take them home and learn cancer more in depth.

Chugai will organize "Team Chugai" and join each venues of "Relay for Life Japan" to enhance the communication with people who participate in the event across the country. As a leading company in the oncology area, Chugai will work to implement cancer treatment that encourages patients to confront their diseases proactively with hope, offering innovative and useful drugs and information on an ongoing basis, and continue to carry out these activities to contribute to healthcare and the society.

LOAd703

LOAd703 is an adenovirus serotype 5/35 armed with TMZ-CD40L and 4-1BBL (Company Web Page, Lokon Pharma, MAY 13, 2016, View Source [SID:1234512342]). TMZ-CD40L and 4-1BBL are two potent stimulators of anti-tumor immunity by their capacity to activate dendritic cells and M1 macrophages to produce IL12, TNFa, IFNg and IL21, as well as to expand both T cells and NK cells.

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10-Q – Quarterly report [Sections 13 or 15(d)]

CohBar has filed a 10-Q – Quarterly report [Sections 13 or 15(d)] with the U.S. Securities and Exchange Commission (Filing, 10-Q, CohBar, 2017, MAY 13, 2016, View Source [SID1234521269]).

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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