David Kendall Joins MannKind as Chief Medical Officer

On February 6, 2018 MannKind Corporation (NASDAQ:MNKD) reported that David M. Kendall, MD, will join the company as Chief Medical Officer and assume full responsibility for leading MannKind’s scientific research, clinical development, regulatory, and medical affairs activity, effective February 12 (Press release, Mannkind, FEB 6, 2018, View Source [SID1234523746]). Dr. Kendall will report directly to Michael Castagna, Pharm.D., Chief Executive Officer, and will join the company’s executive leadership team. He will be based out of MannKind’s Westlake Village, California headquarters.

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"David is a world renowned diabetes expert and represents an important addition to our executive leadership team," said Castagna, Chief Executive Officer of MannKind. "His extensive experience in diabetes research, development, and clinical care in both U.S. and international markets, will be instrumental in helping us achieve the growth potential that we believe Afrezza clearly possesses."

Dr. Kendall’s career includes over 30 years of experience in diabetes and metabolism research, clinical management, research, and policy advocacy. Most recently, he served as Research Physician and Vice President of Global Medical Affairs for Lilly Diabetes, and during that time was responsible for all medical affairs activities and guided research and development strategy across multiple geographies. In this role, he worked to re-establish Lilly Diabetes as a world class medical organization — and added to his extensive experience with both injected and mealtime insulins, as well as devices and continuous glucose monitors. Prior to joining Eli Lilly, Dr. Kendall served as Chief Scientific and Medical Officer at the American Diabetes Association, where he was responsible for all medical affairs, medical education, research, outcomes, and medical policy activities. Earlier in his career, Dr. Kendall served as Medical Director at the International Diabetes Center, and the Park Nicollet Clinic, as well as at Amylin Pharmaceuticals. He received his M.D. and completed his Post Graduate Medical Training at the University of Minnesota, and earned a B.A. in Biology from St. Olaf College.

"The research and clinical response to Afrezza as a mealtime insulin supports ongoing efforts to establish this product as the standard of care for those living with type 1 or type 2 diabetes," said Dr. Kendall. "Afrezza is the only inhaled fast-acting mealtime insulin on the market, and offers the right patients a flexible, safe, and effective treatment option. I’m thrilled to join MannKind, and look forward to being part of a company that has the potential to transform the lives of so many people that are living with diabetes."

SELLAS Life Sciences to Present at Two Upcoming February Investor Conferences

On February 6, 2018 SELLAS Life Sciences Group Inc., (Nasdaq:SLS) (SELLAS), a development-stage biopharmaceutical company focused on novel cancer immunotherapies for a broad range of cancer indications, reported that Angelos Stergiou, M.D., ScD h.c., President and Chief Executive Officer of SELLAS, will present a corporate overview at the following upcoming conferences (Press release, Sellas Life Sciences, FEB 6, 2018, View Source [SID1234523769]).

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BIO CEO & Investor Conference 2018
Date: Tuesday, February 13, 2018
Presentation Time: 2:30 PM ET
Location: New York Marriott Marquis, New York, NY

2018 RBC Capital Markets Healthcare Conference
Date: Wednesday, February 21, 2018
Presentation Time: 2:35 PM ET
Location: Lotte New York Palace Hotel, New York, NY

A live webcast of each presentation can be accessed on the investor page of SELLAS’ website at www.sellaslifesciences.com/investors. A replay of each webcast will also be archived for up to 30 days on SELLAS’ website following the conference.

Varian Halcyon Treatment System Receives AERB Certificate for Import & Supply in India

On February 6, 2018 Varian (NYSE: VAR) reported the Halcyon cancer treatment platform has received Atomic Energy Regulatory Board (AERB) Certificate for Import and Supply in India (Press release, Varian Medical Systems, FEB 6, 2018, View Source [SID1234523896]). This registration allows Varian to now market this new system in India. Halcyon simplifies and enhances virtually every aspect of image-guided volumetric intensity modulated radiotherapy (IMRT), and is well suited to treat a majority of cancer patients, offering advanced treatments for prostate, breast, head & neck, and many other forms of cancer.

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"With AERB No Objection Certificate, clinicians in India now have access to Halcyon, which is engineered to revolutionize the clinical workflow and could help advance cost-effective cancer care across the country," said Ashok Kakkar, senior managing director, Varian India. "We look forward to continuing our close collaboration with clinical partners across India and helping realize a world without fear of cancer."

Halcyon is an advanced system that was designed to improve patient comfort, simplify operations, and shorten the time from installation to first-treatment without sacrificing quality. Its quiet operating environment, which is up to 2x quieter than other systems, has been designed with the patients in mind. Additionally, Halcyon has a low couch height for easy patient access, and soft indirect ambient lighting in the gantry opening.

Featuring a 100cm gantry opening, which is larger than those on standard CT machines, Halcyon is capable of rotations 4x faster than c-arm gantries for rapid imaging and treatment. The system is also capable of fast and sharp volumetric imaging in as little as 15 seconds. With Halcyon treatments, a complex image guided IMRT plan is clinically accelerated compared to those delivered on traditional devices.

Operationally, Halcyon features a streamlined workflow that only requires nine steps from the start to the end of treatment compared to up to more than 30 steps with older technologies. To assist in the reduction of time and construction costs from installation to first patient treatment, Halcyon comes pre-commissioned, requires less shielding than traditional systems, can fit in a vault as small as 5.9 meters (19.68 feet) x 5.539 meters (18.17 feet) x 2.743 meters (8.99 feet) high and can be installed in two weeks or less.

For more information on Halcyon visit www.varian.com/halcyon.

Sierra Oncology to host Program Update in New York on February 27th

On February 6, 2018 Sierra Oncology, Inc. (Nasdaq: SRRA), a clinical stage drug development company focused on advancing next generation DNA Damage Response (DDR) therapeutics for the treatment of patients with cancer, reported it will host a Program Update on Tuesday, February 27th from 10:00 a.m. – 12:00 p.m. Eastern Time (ET) at the Lotte New York Palace in New York, NY (Press release, Sierra Oncology, FEB 6, 2018, View Source [SID1234523747]).

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During the event, the senior management team from Sierra Oncology will present a strategic update on the development programs for its two DDR drug candidates: SRA737, a highly selective, orally bioavailable Chk1 inhibitor; and SRA141, a highly selective, orally bioavailable Cdc7 inhibitor. The company will be joined by Dr. Udai Banerji, Chief Investigator for Sierra’s ongoing SRA737 Phase 1/2 clinical studies, and Dr. Alan D’Andrea, a member of Sierra’s DDR Advisory Committee.

Dr. Udai Banerji is the Cancer Research UK Reader in Molecular Cancer Pharmacology at The Institute of Cancer Research, London, and a Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust. He leads the Clinical Pharmacology and Trials team at The Institute of Cancer Research (ICR) and is the Deputy Director of the Drug Development Unit at the ICR and The Royal Marsden.

Dr. Alan D’Andrea is the Fuller-American Cancer Society Professor of Radiation Oncology at Harvard Medical School and the Director of the Center for DNA Damage and Repair at the Dana-Farber Cancer Institute. Dr. D’Andrea is internationally known for his research in the area of DNA damage and DNA repair, and participates in a wide range of clinical trials, largely focused on ovarian, breast, prostate, and bladder cancers.
Event registration and webcast information are available through the Sierra Oncology website at www.sierraoncology.com. An archive of the presentation will be accessible after the event through the Sierra Oncology website.

BIO CEO & Investor Conference in New York
Dr. Nick Glover, President and Chief Executive Officer, will present an overview of the company, scheduled for 11:30 a.m. ET on Monday, February 12th at the BIO CEO & Investor Conference being held in New York, NY. A live audio webcast and archive of the presentation will be accessible through the Sierra Oncology website at www.sierraoncology.com.

Valeant Will Release Fourth-Quarter And Full-Year 2017 Financial Results On February 28

On February 6, 2018 Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX) ("Valeant") reported that it will release its fourth-quarter and full-year 2017 financial results on Wednesday, Feb. 28, 2018 (Press release, Valeant, FEB 6, 2018, http://ir.valeant.com/news-releases/2018/02-06-2018-152552266 [SID1234523770]). Valeant will host a conference call and live web cast at 8:00 a.m. EST to discuss the results and provide a business update. All materials will be made available on the investor relations section of the Valeant web site prior to the start of the call.

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Conference Call Details

Date:

Wednesday, Feb. 28, 2018

Time:

8:00 a.m. EST

Webcast:

http://ir.valeant.com/events-and-presentations

Participant Event Dial-in:

(844) 428-3520 (North America)

(409) 767-8386 (International)

Participant Passcode:

5287247

Replay Dial-in:

(855) 859-2056 (North America)

(404) 537-3406 (International)

Replay Passcode:

5287247 (replay available until Apr. 28, 2018)