Sensei Biotherapeutics to Present Preclinical Data on SNS-103 at the CRI-ENCI Eighth International Immunotherapy Conference

On September 4, 2024 Sensei Biotherapeutics, Inc. (Nasdaq: SNSE), a clinical stage immuno-oncology company focused on the discovery and development of next-generation therapeutics for cancer patients, reported that preclinical data on SNS-103 will be presented in a poster session at the CRI-ENCI Eighth International Immunotherapy Conference, being held September 8-11, 2024, at the Gaylord National Resort & Convention Center in National Harbor, MD (Press release, Sensei Biotherapeutics, SEP 4, 2024, View Source [SID1234646346]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Presentation Details:

CRI-ENCI Eighth International Cancer Immunotherapy Conference (CIMT) (Free CIMT Whitepaper)
Title: Pre-clinical characterization of monoclonal antibodies targeting CD39 activity in the acidic tumor microenvironment
Presenter: F. Donelson Smith, Ph.D., Senior Director, Biologics Discovery & Early Development
Poster Number: 195A
Date and time: Sunday, September 8, 2024, 12:05 – 2:05 p.m. EDT

HEPTA Medical Secures €5.7 Million Series A, Led by BPI France to Advance Minimally Invasive Lung Cancer Treatment

On September 4, 2024 HEPTA Medical ("HEPTA"), a private medical device company dedicated to providing an efficient, safe, and minimally-invasive thermal ablation therapy for early-stage lung cancer, reported it has successfully raised €5.7M in the first close of its Series A funding round (Press release, Hepta Medical, SEP 4, 2024, View Source [SID1234646362]). The investment was led by BPI France with the participation of M&L Healthcare and Clery IG.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

This financing round will enable HEPTA to initiate the US regulatory approval process for the first version of its microwave ablation platform and to commence its clinical trials. Lung cancer is the leading cause of cancer-related deaths worldwide. As lung cancer screening programs are being implemented, the management of early-stage lung cancer patients has become an increasingly urgent concern for healthcare organizations. HEPTA aims to address this need by offering a controlled, incision-less technology, that provides a minimally invasive approach to treat patients quickly, safely, and efficiently.

"We are grateful for our new investors, and excited to bring microwave ablation therapy to new heights. In August, we obtained our first proprietary patent, completing our three patent families under license. We have multiple upcoming milestones, including the release of early preclinical trial results conducted in collaboration with world-renowned centers, which we’ll publish at the CIRSE conference in September," says Dr. Thomas Bancel, CEO of HEPTA Medical.

The chairman of the board of directors, Gérard Hascoët, a Sofinnova Venture Partner, will be joined by Philippe Boucheron and Jocelyn Kum as representatives for BPI France and M&L Healthcare, respectively.

"We are thrilled to be part of HEPTA Medical’s journey as they push the boundaries of innovation in minimally invasive lung cancer treatment. This investment aligns with our commitment to support groundbreaking medical technologies that have the potential to significantly improve patient outcomes. HEPTA’s unique approach to thermal ablation therapy, combined with their dedicated team and cutting-edge technology, positions them at the forefront of transforming lung cancer care. We are confident that HEPTA Medical will achieve significant milestones in the near future and are excited to support their continued growth and success," comments Philippe Boucheron, Deputy Chief of Life Sciences Investments at BPI France.

HEPTA Medical was founded in 2019 by Sofinnova medtech acceleration team, MD Start. HEPTA develops a flexible microwave ablation probe compatible with any lung navigation system. It is equipped with a proprietary patented tissue temperature sensor that enables monitoring of the growth of the ablation zone in-situ and in real-time during endobronchial ablation procedures. The device also incorporates predictive software, powered by artificial intelligence, which combines procedural CT images and temperature measurements to display the ablation zone in real-time to the clinician during the procedure.

Anixa Biosciences Announces Presentation on its Ovarian Cancer CAR-T Therapy at the Rivkin Center-AACR 15th Biennial Ovarian Cancer Research Symposium

On September 3, 2024 Anixa Biosciences, Inc. ("Anixa" or the "Company") (NASDAQ: ANIX), a biotechnology company focused on the treatment and prevention of cancer, reported that the inventor of its ovarian cancer CAR-T technology, Jose R. Conejo-Garcia, M.D., Ph.D., Professor of Immunology in the Department of Integrative Immunobiology at the Duke University School of Medicine, will be speaking at the Rivkin Center and American Association for Cancer Research (AACR) (Free AACR Whitepaper) 15th Biennial Ovarian Cancer Research Symposium (Press release, Anixa Biosciences, SEP 3, 2024, View Source [SID1234646280]). Dr. Conejo-Garcia will be giving the opening keynote address on Friday, September 20, 2024.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

During the keynote address, Dr. Conejo-Garcia will discuss Anixa’s chimeric antigen receptor-T cell (CAR-T) technology, which is an autologous cell therapy comprised of engineered T cells that target the follicle stimulating hormone receptor (FSHR). FSHR is found at immunologically relevant levels exclusively on the granulosa cells of the ovaries. Since the target is a hormone (chimeric endocrine) receptor, and the target-binding domain is derived from its natural ligand, this technology is known as CER-T (chimeric endocrine receptor-T cell) therapy, a new type of CAR-T. Anixa holds an exclusive world-wide license to the technology from The Wistar Institute. Dr. Conejo-Garcia will also discuss the ongoing Phase 1 clinical trial of this technology.

"I am pleased to discuss this novel FSHR-mediated CAR-T technology at the Ovarian Cancer Research Symposium and to share ideas and advance the field of ovarian cancer research," stated Dr. Conejo-Garcia. "Anixa and its development partner, Moffitt Cancer Center, have been working together to advance this ovarian cancer therapy and we are excited about the clinical results to date—with the treatment appearing to be safe and well-tolerated, and some patients exhibiting tumor necrosis. If this therapeutic approach is successful, this could enable a major shift in the overall treatment paradigm for ovarian cancer."

More information about the event may be found at: View Source

Karyopharm to Participate at Upcoming Investor Conferences

On September 3, 2024 Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, reported that the Company’s senior management team will participate in the following investor conferences in September (Press release, Karyopharm, SEP 3, 2024, View Source [SID1234646297]):

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

H.C. Wainwright 26th Annual Global Investment Conference
Format: Podium presentation
Date: Tuesday, September 10, 2024
Time: 9:00 a.m. ET

Baird 2024 Global Healthcare Conference
Format: Fireside chat
Date: Wednesday, September 11, 2024
Time: 10:50 a.m. ET

A live webcast of these events, along with accompanying slides, can be accessed under "Events & Presentations" in the Investor section of the Company’s website, View Source, and will be available for replay following the event.

Cue Biopharma to Present at The Promise of Interleukin-2 Therapy Conference

On September 03, 2024 Cue Biopharma, Inc. (Nasdaq: CUE), a clinical-stage biopharmaceutical company developing a novel class of therapeutic biologics to selectively engage and modulate disease-specific T cells, reported that members of its management team will deliver two presentations at The Promise of Interleukin-2 Therapy Conference, taking place September 4-7, 2024 in Paris, France. (Press release, Cue Biopharma, SEP 3, 2024, View Source [SID1234646313]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Presentation Details
Date and Time: Friday, September 6, 2024, 4 p.m. CET
Presentation Title: CUE-401: A Novel IL-2/TGF-beta fusion protein for the induction & expansion of FOXP3+ regulatory T Cells
Presenter: Steven Quayle, Ph.D., vice president & head, Biology Research & Translational Medicine, Cue Biopharma

Dr. Quayle will present preclinical data on our first-in-class bispecific fusion protein, CUE-401, which induces and expands regulatory T cells (Tregs) through the co-delivery of interleukin 2 (IL-2) and transforming growth factor beta (TGF-β), and how this approach differentiates from other Treg-directed therapies.

Date and Time: Saturday, September 7, 2024, 9 a.m. CET
Presentation title: Clinical safety and efficacy of TCR-specific engagers that selectively target IL-2 to tumor-specific T cells
Presenter: Matteo Levisetti, M.D., chief medical officer, Cue Biopharma

Dr. Levisetti will discuss how the company’s lead oncology programs CUE-101 and CUE-102, representative of the CUE-100 series of Immuno-STAT biologics, enable selective targeting of the cytokine IL-2 to tumor specific T cells for enhanced efficacy and safety profiles.