On April 7, 2026 Nurix Therapeutics, Inc. (Nasdaq: NRIX), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of targeted protein degradation medicines, reported that Arthur Sands, M.D., Ph.D., president and chief executive officer of Nurix, will participate in a fireside chat at the 25th Annual Needham Virtual Healthcare Conference in April.

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Needham Virtual Healthcare Conference
Arthur T. Sands, M.D., Ph.D., president and chief executive officer of Nurix
Monday, April 13, 2026, at 1:30 – 2:10 p.m. ET
The fireside chat will be webcast live and may be viewed via a link in the Investors section of the Nurix website. The archived webcast will be available for 30 days after the event.

(Press release, Nurix Therapeutics, APR 7, 2026, View Source [SID1234664210])

On April 7, 2026 Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (CAR) T-cell therapies for patients with cancer, reported that members of its senior management team will present and participate in the 25th Annual Needham Virtual Healthcare Conference on Tuesday, April 14, 2026, at 11:00 am Eastern Time.

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A live webcast of the presentation can be accessed through the Investors section of the Company’s website at www.lyell.com. A replay of the webcast will be available on the Company’s website following the presentation date.

(Press release, Lyell Immunopharma, APR 7, 2026, View Source [SID1234664226])

On April 7, 2026 Sona Nanotech Inc. (CSE: SONA, OTCQB: SNANF) (the "Company", "Sona") reported publication of a preclinical study using its Targeted Hyperthermia Therapy ("THT") to treat cancer, in the Journal of Nanobiotechnology which demonstrated treatment durability to the end of the 45 day study period when it was given in combination with immunotherapy. Building on its prior body of preclinical research treating melanoma and breast cancer (as published in Frontiers in Immunology), this study was conducted in an immunologically ‘cold’ colorectal cancer (CT26) tumor model. In this combination protocol, CT26 tumor-bearing animals were treated with two consecutive treatments of THT plus standard PD-1 inhibitor immunotherapy followed by three additional PD-1 treatments (the "Study"). Animals were followed for 45 days following initiation of treatment as per study protocol. At completion of the Study 38% of animals given the combined therapy were alive and disease free.

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Sona Nanotech CEO, David Regan commented, "We’ve all recently heard the shocking news that colon cancer is now the leading cause of cancer death for adults under 50. This timely preclinical evidence of strong immune activation in colon cancer using our THT/immunotherapy combination protocol reaffirms our confidence in pursuing Sona’s THT to spark immunity in typically immunotherapy resistant cancers. We are certainly proud of the quality of this peer-reviewed research and its acceptance in the highly respected Journal of Nanobiotechnology. This study, together with the safety and tolerability data from our recently completed, first-in-human study of THT as a monotherapy in melanoma, lays the foundation for our next trial that will combine our THT with immunotherapy."

Study principal investigator, lead author and Sona Chief Medical Officer, Dr. Carman Giacomantonio, commented, "We have focused our preclinical research on immunogenically cold cancers i.e. cancers that do not respond to today’s standard-of-care immunotherapy, to prove our hypothesis that Sona’s THT activates immunity. This is the third preclinical cancer-type in which we have confirmed our hypothesis, and our first publication delving deeply into the biology of our treatments. In this study, where no animals responded to a standard immunotherapy alone, 100% of animals in the THT treatment group responded to that same immunotherapy. This relates incredibly favorably to the less than ~15% success rate of immunotherapy when used to treat colorectal cancer in most humans due to low immunogenicity, giving us tremendous hope for its ability to change lives if translated successfully into a human therapy. Importantly, 38% (8 of 21) of those tumors completely cleared by day 24 following initiation of treatment and remained cancer-free to the end of the study. This is remarkably fast by any standard of measure, and these important findings will inform the protocol for our next clinical study."

(Press release, Sona Nanotech, APR 7, 2026, View Source [SID1234664211])

On April 7, 2026 Autolus Therapeutics plc (Nasdaq: AUTL), a commercial-stage biopharmaceutical company developing, manufacturing and delivering next-generation programmed T cell therapies, reported that the Company will participate in two upcoming investor conferences.

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25th Annual Needham Virtual Healthcare Conference
Date and time: April 13, 2028; 10:15am EDT / 3:15pm BST
Presenter: Chief Executive Officer Dr. Christian Itin

A webcast of the presentation will be available on the "Events" page in the "Investor Relations & Media" section of the Company’s website at View Source A replay of the webcast will be archived on the Company’s website for 90 days following the presentation.

Van Lanschot Kempen Life Sciences Conference
Management to host investor meetings
Date: April 16, 2026
Location: Amsterdam

(Press release, Autolus, APR 7, 2026, View Source [SID1234664227])

On April 7, 2026 TransCode Therapeutics, Inc. (NASDAQ: RNAZ, the "Company"), a clinical stage company pioneering immuno-oncology and RNA for the treatment of high risk and advanced cancer, reported that it has entered into an agreement with an institutional healthcare investor for financing of up to $20 million. The arrangement comprises pre-paid advances of up to $6 million and a three-year Standby Equity Purchase Agreement (SEPA) providing the Company the right to sell up to $14 million of its common stock to the investor, subject to certain conditions.

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"The financing agreement provides TransCode with financial flexibility and ensures that TransCode can maintain operational momentum as we conduct our Phase 2a trial for our lead clinical program, TTX-MC138," said Dr. Philippe P Calais, Pharm.D., Ph.D., Chairman and CEO of TransCode. "This runway extension should enable the Company to complete the Phase 2a study and subsequently explore a strategic collaboration for the program," said Tom Fitzgerald, CFO of TransCode.

About TTX-MC138

TTX-MC138 is a first-in-class therapeutic candidate designed to inhibit microRNA-10b, or miR-10b, a microRNA widely believed to be critical to the emergence and progression of many metastatic cancers. TransCode’s Phase 0 clinical trial produced evidence of delivery of a radiolabeled version of TTX-MC138 to metastatic lesions and pharmacodynamic activity, even at a microdose of the drug candidate, suggesting a broad therapeutic window for TTX-MC138. In the Company’s Phase 1a clinical trial, TTX-MC138 met its safety endpoint and was well tolerated by patients. A Phase 2a clinical trial with TTX-MC138 is expected to begin in the second quarter 2026.

About the Financing Transaction

The pre-paid advance will be evidenced by convertible promissory notes priced at 95% of face value. TransCode will issue a $1 million principal amount note concurrently with the Company’s Annual Report on Form 10-K for the year ended December 31, 2025, and, subject to certain closing conditions, will issue an additional $5 million principal amount note upon shareholder approval of the transaction as required by Nasdaq rules. The advance will accrue interest at a simple annual rate of 5% and may be converted into TransCode’s common stock.

Upon conversion or repayment of the convertible notes, TransCode at its option may sell up to $14 million of its common stock to the investor under terms specified in the financing agreement.

The financing agreement can be found in TransCode’s Form 8-K filed with the U.S Securities and Exchange Commission.

Tungsten Advisors acted as the Sole Placement Agent.

(Press release, TransCode Therapeutics, APR 7, 2026, View Source [SID1234664212])