On July 27, 2022 Akoya Biosciences, Inc. (Nasdaq: AKYA) ("Akoya"), The Spatial Biology Company, reported that it will be participating in two upcoming investor conferences (Press release, Akoya Biosciences, JUL 27, 2022, View Source [SID1234616993]).

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UBS Genomics 2.0 and MedTech Innovation Conference
Fireside Chat – Brian McKelligon, Chief Executive Officer, and Niro Ramachandran, Chief Business Officer, will participate in a fireside chat on Tuesday, August 9th at 1:00 PM PT.
Canaccord Growth Conference
Panel: The New Frontier of Life Sciences: Spatial Omics is Transforming Biological Analysis – Brian McKelligon, Chief Executive Officer, will participate in a panel discussion on Wednesday, August 10th at 12:00 PM ET. Canaccord Genuity has arranged for all presentations to be broadcasted live and available for replay via the conference portal for 14 days.

On July 27, 2022 Kura Oncology, Inc. (Nasdaq: KURA), a clinical-stage biopharmaceutical company committed to realizing the promise of precision medicines for the treatment of cancer, reported that it will report second quarter 2022 financial results after the close of U.S. financial markets on Wednesday, August 3, 2022 (Press release, Kura Oncology, JUL 27, 2022, View Source [SID1234617009]). Kura’s management will host a webcast and conference call at 4:30 p.m. ET / 1:30 p.m. PT that day to discuss the financial results and provide a corporate update.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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To participate in the teleconference, domestic callers should dial 1-888-882-4478 and international callers should dial 1-323-794-2590 and reference conference ID: 8696904. A live webcast presentation can also be accessed using this weblink: View Source;tp_key=10754ad253. A replay of the webcast will be available online from the investor relations section of the company website at www.kuraoncology.com.

On July 27, 2022 Humanetics Corporation reported that paper in Radiation Research, the official journal of the Radiation Research Society, details the results from a series of pharmacokinetics (PK) studies conducted with it’s (Humanetics) new radioprotective drug, BIO 300 (Press release, Humanetics, JUL 27, 2022, View Source [SID1234617025]). The studies, which were conducted by researchers at the University of Maryland Schools of Medicine and Pharmacy (UMB), compared the PK of BIO 300 using oral, subcutaneous, and intramuscular dosing. These nonclinical studies also examined the effect of radiation exposure on the PK of BIO 300. The researchers concluded that the effect of irradiation on the PK of BIO 300 is minimal, an important finding for use of the drug during radiation emergencies or during cancer radiotherapy treatments.

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Exposure to radiation can lead to acute radiation syndrome (ARS), which consists of numerous serious and life-threatening injuries. Survivors of ARS are at risk of developing delayed effects of acute radiation exposure (DEARE), which include a multitude of chronic injuries, notably to the lungs. There are currently no FDA-approved drugs that prevent ARS or DEARE. Humanetics is developing BIO 300 as a medical countermeasure (MCM) for use by the military, first responders, and in civilian populations that have been exposed, or may become exposed, to radiation to prevent or mitigate both ARS and DEARE.

"Our ongoing collaboration with colleagues at UMB has been instrumental in the development of BIO 300 for use as a MCM," said Ronald Zenk, CEO of Humanetics. "Current events in Ukraine and global threats of nuclear incidents point to the urgent need for drugs like BIO 300."

BIO 300 is also in clinical development for oncology applications to protect cancer patients from unintentional side effects caused by radiation therapy. Humanetics recently completed a phase 1b/2a clinical trial in lung cancer patients (NCT02567799). In addition, a phase 2b trial is currently in progress evaluating the clinical utility of BIO 300 to protect lung tissues against the long-term effects of COVID-19 (NCT04482595).

On July 27, 2022 SHINE Technologies, LLC (SHINE), a next-generation nuclear technology company, reported the company has submitted a Drug Master File (DMF) with the U.S. Food and Drug Administration for non-carrier-added lutetium-177 (Lu-177) chloride, a radiopharmaceutical at the forefront of precision cancer treatment (Press release, Shine Medical Technologies, JUL 27, 2022, View Source [SID1234618509]).

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In targeted cancer therapy, the cancer-killing radioisotope Lu-177 is paired with a cancer-seeking molecule to form a smart compound that directly targets and attacks cancer cells.

SHINE is the emerging leader in the production of this medical radioisotope. With its proprietary technology, SHINE intends to be the industry’s only vertically integrated producer of Lu-177, providing a reliable and scalable supply without the need for aging nuclear reactors.

The DMF submission provides confidential detailed information about facilities, procedures, or articles used in the manufacturing, processing, and storing of drugs. It is a clear commitment to the several companies that have requested letters of authorization to access SHINE’s drug master file in support of their clinical trials which are underway to fight cancer. And it is also an important step in SHINE’s path to meeting the increasing global demand for Lu-177.

"As global demand for lutetium-177 increases, SHINE is poised to scale our operations and be the preferred partner for customers seeking a high-quality, reliable supply of lutetium-177," said Chris Vessell, general manager of SHINE’s Therapeutics Division.

"We’ve been producing lutetium-177 that meets or exceeds customer specifications for some time now, and the DMF submittal represents the next step in getting our product into regular commercial use." said Greg Piefer, founder and CEO of SHINE Technologies. "We’re looking forward to growing our vertically-integrated and sustainable process to ensure the world has scalable access to these game-changing, cancer-destroying products as new therapies are approved."

On July 27, 2022 Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on developing novel therapeutics to address unmet medical needs in viral and liver diseases, reported that it will report the company’s second quarter 2022 financial results on Thursday, August 4, 2022 after the close of the U.S. financial markets (Press release, Aligos Therapeutics, JUL 27, 2022, View Source [SID1234616994]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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