Doma Raises RMB 950 Million Series A Financing to Incubate Innovative Life Sciences Companies

On June 1, 2022 Doma Biopharmaceutical reported the closing of a Series A financing round of RMB 950 million (Press release, Doma Biopharmaceutical, JUN 1, 2022, View Source [SID1234636146]). The investors included Biocytogen, China Life Private Equity Investment, PICC Capital, SDIC Venture Capital, Suzhou Industrial Park, Taiping Healthcare Fund, and CMB International. As the founding shareholders of Doma Pharmaceutical, the investors aspired to build the company into a China-based integrated incubator for sustained life sciences innovations by pooling cutting-edge technologies, outstanding talents, and longterm capital inputs.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Doma was established in Suzhou BioBAY in September 2021 with a vision to develop innovative drugs and disruptive biotechnologies. The company has successfully incubated dynamic biotech companies with novel proprietary drug pipelines/biotechnologies, while giving birth to an industry cluster for innovative life sciences. That has been made possible by the company’s optimal integration of talents, technologies/products and capital on the shareholders’ robust open R&D service platform. As a fully integrated incubator for life science innovations, the company will empower incubatees with diverse.

"We are grateful to our founding shareholders for their contributions to the Series A financing, which has set the company in motion," said Dr. Huang Rui, Director and Chief Operating Officer of Doma. "The past decade has seen rapid progress in life sciences research in China and an increasing number of qualified and experienced high-caliber talents in the industry. That has given us the confidence to integrate science, industry, talent, and capital resources to build the company into a fully integrated incubation platform for life science innovations in China. On this platform, we will create a series of innovative and vibrant biotech companies that seek to address real clinical needs, identify market value, improve public health, and realize sustainable development by taking groundbreaking approaches. Going forward, Doma aims to incubate world-class companies based in China. That entails joint efforts with technology innovators, top talents, investors, and industrial partners to develop innovative target drugs, dual anti-ADC drugs, oncolytic viruses, cell therapies, pet drugs, diagnostic reagents, and AI products."

"We are honored to be a part in the co-investment for the establishment of Doma," said Dr. Shen Yuelei, Chairman of Biocytogen, one of the founding shareholders. "Biocytogen boasts world-leading technology platforms for gene editing, antibody drug discovery and screening, innovative animal model development, and clinical drug development, as well as the ability to develop new drugs throughout the process from early target validation to preclinical research and clinical development of pharmaceutical molecules. Besides, Biocytogen’s Project Integrum program and unique drug development platform will bolster Doma’s R&D capabilities, helping the company incubate more innovative and dynamic biotech.

"It is a trend inevitable for China to become a pharmaceutical powerhouse through rapid construction of a biopharma innovation incubator and a biopharma industry cluster with global influence, while platform companies have emerged as one of the key drivers to enhance the industrial capacity," said Jiang Li, Managing Director of China Life Private Equity Investment. "Doma is incubating new antibody drug companies with premier biopharma talents at home and abroad working on Biocytogen’s antibody drug development service platform and the unique Project Integrum platform. A bright future can be anticipated from its distinctive operating model that combines industrial incubation and drug pipeline development. We hope that our collaboration with Biocytogen and Doma will result in greater concentration and flow of advanced technologies, high-end talents, abundant capital, and other innovation factors, faster commercialization of scientific and technological findings, incubation of more new biotech companies, and globalization of local businesses. These outcomes will ultimately accelerate China’s bioeconomy growth and secure strategic advantages, while providing humanity with more innovative and effective pharmaceuticals."

"Life sciences is a subject that keeps exploring new ways to prolong life and cure illness, carrying the hopes and expectations of all mankind," said Shu Wanting, Managing Director of PICC Capital. "To embark on a novel industrial growth path, China must be an innovator rather than a follower, while being more patient and persistent along the way. We are very pleased to be one of the founding shareholders of Doma, standing ready to contribute to the company’s biotech industry cluster incubation by combining our extensive industry experience, top-tier talents, and long-term capital inputs with those of other shareholders. We hope that Doma will soon roll out a series of new products that will make a big difference in treating diseases and extending people’s lives.

Flagship Pioneering, a world-renowned biotech incubator, a biotech platform should be versatile within the same sector and able to quickly adapt successful R&D cases to succeeding R&D processes within the same sector. The more versatile a biotech platform is, the more functional and valuable it becomes. With its unique industry incubation system and Biocytogen’s Project Integrum resources, Doma has the potential to become an excellent biotech platform. We expect the company to become ‘China’s Flagship Pioneering’."

Theolytics’ £1M project with InnovateUK to develop a novel therapy for multiple myeloma patients

On June 1, 2022 Theolytics is a biotechnology company harnessing viruses to combat disease reported the company has been awarded a Biomedical catalyst grant by Innovate UK to progress a novel therapy for multiple myeloma patients (Press release, Theolytics, JUN 1, 2022, View Source [SID1234630918]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Multiple myeloma is an incurable blood cancer, for which cancer-killing (‘oncolytic’) viruses are an emerging therapy offering hope. The therapy selectively infects and kills cancer cells – targeting heterogeneous, systemic cancers based on their phenotype rather than molecular targets, providing the promise of durable remission and curative potential.

This grant will focus on translating Theolytics’ lead candidate to clinic-readiness. The work includes partnering with the University of Sheffield to investigate the efficacy of Theolytics’ lead candidate

in clinically representative, drug-resistant models of multiple myeloma. This project will further validate this novel therapy, positioning the lead oncolytic virus candidate for testing in Phase I clinical trials.

Margaret Duffy, Chief Scientific Officer and Co-Founder said: "The myeloma treatment landscape has changed considerably in recent years; despite some promising clinical results with BCMA targeted therapies, lasting remissions remain a challenge for many myeloma patients. Due to the unique mechanism of this oncolytic virus candidate, we wish to offer hope to those with advanced, refractory disease. This grant provides the opportunity to advance our candidate to the clinics and we are grateful to Innovate UK for their continued support of Theolytics’ work."

Michelle Lawson, Academic Collaborator, University of Sheffield said: "I am absolutely thrilled to be working in collaboration with Theolytics on this exciting project to further demonstrate the efficacy of their lead candidate in our preclinical models of myeloma, as subsequent in-patient use could ultimately lead to much-needed improvements in outcomes for myeloma patients with advanced disease."

Bicycle Therapeutics to Participate in the Jefferies Healthcare Conference

On June 1, 2022 Bicycle Therapeutics plc (NASDAQ: BCYC), a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle) technology, reported that management will participate in a fireside chat at the Jefferies Healthcare Conference in New York, NY on Wednesday, June 8, 2022 at 8:00 a.m. ET (Press release, Bicycle Therapeutics, JUN 1, 2022, View Source [SID1234615317]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

A live webcast of the fireside chat will be accessible in the Investors and Media section of Bicycle’s website at www.bicycletherapeutics.com. An archived replay of the webcast will be available for 90 days following the fireside chat date.

Alkermes to Participate in the Jefferies Healthcare Conference

On June 1, 2022 Alkermes plc (Nasdaq: ALKS) reported that management will participate in a fireside chat at the Jefferies Healthcare Conference on Wednesday, June 8, 2022 at 2:30 p.m. ET (7:30 p.m. BST) (Press release, Alkermes, JUN 1, 2022, View Source [SID1234615333]). The live webcast may be accessed under the Investors tab on www.alkermes.com and will be archived for 14 days.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!


Wugen to Participate in Upcoming June Investor Conferences

On June 1, 2022 Wugen, Inc., a clinical-stage biotechnology company developing a pipeline of off-the-shelf cell therapies to treat a broad range of hematological and solid tumor malignancies, reported that management will participate in two upcoming investor conferences in June (Press release, Wugen, JUN 1, 2022, View Source [SID1234615351]):

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Jefferies Healthcare Conference
Format: Presentation
Presentation Date/Time: Wednesday, June 8, 2022 at 4:30 p.m. ET
Location: New York City

2022 Truist Securities Symposia
Format: Panel titled "Novel Engineered NK Cell Therapies: Pursuit of The Right Phenotype"
Presentation Date/Time: Tuesday, June 28, 2022 at 11:00 a.m. ET
Location: New York City