On February 3, 2025 BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) (TSX: BCT) ("BriaCell" or the "Company"), a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care, reported that it intends to offer to sell common shares in a best-efforts public offering (Press release, BriaCell Therapeutics, FEB 3, 2025, View Source [SID1234650079]). The offering is subject to market conditions and there can be no assurance as to whether or when the offering may be completed, or as to the size or terms of the offering. The Company is relying upon the exemption set forth in Section 602.1 of the TSX Company Manual, which provides that the TSX will not apply its standards to certain transactions involving eligible interlisted issuers on a recognized exchange, such as Nasdaq.

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ThinkEquity is acting as sole placement agent for the offering.

The Company intends to use the net proceeds from the offering primarily for working capital requirements, general corporate purposes, and the advancement of business objectives.

The securities will be offered and sold pursuant to a shelf registration statement on Form S-3 (File No. 333-276650), including a base prospectus, filed with the U.S. Securities and Exchange Commission (the "SEC") on January 22, 2024 and declared effective on January 31, 2024. The offering will be made only by means of a written prospectus. A preliminary prospectus supplement and accompanying prospectus describing the terms of the offering has been or will be filed with the SEC on its website at www.sec.gov. Copies of the preliminary prospectus supplement and the accompanying prospectus relating to the offering may also be obtained from the offices of ThinkEquity, 17 State Street, 41 st Floor, New York, New York 10004. Before investing in this offering, interested parties should read in their entirety the preliminary prospectus supplement and the accompanying prospectus and the other documents that the Company has filed with the SEC that are incorporated by reference in such preliminary prospectus supplement and the accompanying prospectus, which provide more information about the Company and such offering.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such state or jurisdiction.

On February 3, 2025 OmniAb, Inc. (NASDAQ: OABI) reported that management will be participating in two investor conferences during the month of March (Press release, OmniAb, FEB 3, 2025, View Source [SID1234650004]).

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TD Cowen 45th Annual Health Care Conference, March 3-5 at the Boston Marriott Copley Place. Management will be presenting a corporate overview on Tuesday, March 4that 2:30 p.m. Eastern time and will be holding one-on-one meetings with investors.
2025 Leerink Partners Global Healthcare Conference, March 9-12 at the W Hotel South Beach in Miami.Management will hold one-on-one meetings with investors on Wednesday, March 12th.

On February 3, 2025 Abeona Therapeutics Inc. (Nasdaq: ABEO) reported that it has granted equity awards to new non-executive employees who joined the Company (Press release, Abeona Therapeutics, FEB 3, 2025, View Source [SID1234649990]). The equity awards were approved in accordance with Nasdaq Listing Rule 5635(c)(4).

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On January 31, 2024, the Compensation Committee of Abeona’s Board of Directors granted restricted stock equity awards as a material inducement to employment to eight individuals hired by Abeona, which equity awards relate to, in the aggregate, up to 13,000 restricted shares of Abeona common stock. One-third of the shares subject to such restricted stock awards will vest yearly on each anniversary of the Grant Date, such that the shares subject to such restricted stock awards granted to each employee will be fully vested on the third anniversary of the Grant Date, in each case, subject to each employee’s continued employment with Abeona on the applicable vesting dates.

On February 3, 2025 Bavarian Nordic A/S (OMX: BAVA) reported preliminary, unaudited financial results for 2024 and provided its financial guidance for 2025 (Press release, Bavarian Nordic, FEB 3, 2025, View Source [SID1234650006]).

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The preliminary revenue in 2024 was DKK 5,716 million and was comprised of the following:

Revenue from Public Preparedness was DKK 3,206 million, reaching the midpoint of the guided interval of DKK 3,000 – 3,400 million. This is more than 1,000 million above the projected base business and reflects another spike year of sales, as the Company addressed the second public health emergency for mpox.
Revenue from Travel Health increased by 22% to DKK 2,287 million, compared to a guidance of DKK 2,200 million. The strong performance was in particular driven by Rabipur/RabAvert and Encepur.
Other revenue totaled DKK 223 million.
The preliminary operating result (EBITDA) was a profit of DKK 1,603 million, corresponding to an EBITDA-margin of 28%, in line with the guided interval of DKK 1,450 – 1,700 million and a margin of 27-29%.

"We delivered strong results in 2024 after an extraordinary performance in our Travel Health business, demonstrating a 22% growth year-over-year, combined with additional mpox vaccine orders, as we made significant strides in strengthening the public health response in Africa and other regions during the current outbreak. Thus, we exceeded our base projections for the Public Preparedness business, which will continue into 2025," said Paul Chaplin, President and CEO of Bavarian Nordic. "Our portfolio continues to grow, and we are truly excited to launch our chikungunya vaccine for travelers over 12 years in both Europe and the US later this year, while also continuing to expand our partnerships to improve access to critical vaccines for vulnerable populations around the globe. Looking into 2025, we have other important milestones in sight, including the completion of the tech transfer of the rabies and TBE vaccines, as well as the payment of the final considerations for our recent acquisitions, which will further strengthen our financial position and flexibility going forward."

The consolidated, audited financial results for 2024 will become available on March 5, 2025, in connection with the publication of the Company’s Annual Report for 2024.

DKK million

FY 2024 guidance
original, 21-Feb-2024

FY 2024 guidance

latest, 26-Sep-2024

FY 2024 actuals
preliminary, unaudited

Revenue

5,000 – 5,300

5,400 – 5,800

5,716

EBITDA

1,100 – 1,350

1,450 – 1,700

1,603

2025 financial guidance
For 2025, Bavarian Nordic expects revenue of DKK 5,700 – 6,700 million and an EBITDA-margin of 26-30%.

DKK million

FY 2025 guidance

Revenue

5,700 – 6,700

EBITDA-margin

26% – 30%

The expected revenue is comprised of DKK 3,000 – 4,000 million from Public Preparedness vaccines, of which DKK 2,500 million have already been secured by contracts. Furthermore, approximately DKK 2,500 million from Travel Health vaccines, and approximately DKK 200 million from contract work are expected.

Travel Health revenue includes DKK 50 – 100 million from the sale of chikungunya vaccines, which is expected to be launched in the US and key European markets later in 2025, pending regulatory approval.

As communicated in early 2024, Bavarian Nordic expects an average annual growth of 10-12% in Travel Health during 2023-2027, and a Public Preparedness base business of DKK 1,500 – 2,000 million annually. With 22% growth in 2024 and the additional growth expected in 2025 for Travel Health combined with the current order book for Public Preparedness, the Company is currently ahead of these ambitions.

The normal seasonality of the Travel Health business and the timing of revenue recognition of orders from Public Preparedness will cause variability in revenue and EBITDA throughout the year, with the first quarter of 2025 being light.

Research and development costs of approximately DKK 900 million are expected, which include cost for life-cycle management of the growing commercial portfolio, including additional studies of the chikungunya vaccine as agreed with the regulatory authorities as well as the advancement of early-stage pipeline assets.

CAPEX is expected at approximately DKK 250 million whereas inventory levels are anticipated to be relatively unchanged.

The outlook is based on the following assumptions on currency exchange rates of DKK 7.00 per 1 USD and DKK 7.45 per 1 EUR.

On February 3, 2025 Alpha Tau Medical Ltd. ("Alpha Tau", or the "Company") (NASDAQ: DRTS, DRTSW), the developer of the innovative alpha-radiation cancer therapy Alpha DaRT, reported an approval from the U.S. Food and Drug Administration (FDA) of an Investigational Device Exemption (IDE) supplement to the IDE previously announced on Jan 27, 2025, which had approved a clinical study examining the combination of Alpha DaRT and first-line chemotherapy in 12 patients with newly diagnosed metastatic pancreatic cancer, allowing expansion of the clinical trial to a broader group of pancreatic cancer patients (Press release, Alpha Tau Medical, FEB 3, 2025, View Source [SID1234649991]).

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The IDE supplement allows the Company to include an additional cohort for locally advanced pancreatic cancer patients, and to increase the number of each cohort to 15 patients, for a total of 30 patients across the two cohorts, at up to 10 U.S. clinical trial sites.

Alpha Tau CEO Uzi Sofer commented, "Following the incredible data that we released last week, analyzing disease control and overall survival in pancreatic cancer patients treated with Alpha DaRT, we welcome the news of this IDE supplement as we continue to move forward, full steam ahead, in our efforts to explore a new treatment for patients with this deadly disease as quickly as possible."