Telix to Collaborate With Kettering Health on Diagnostic PSMA Imaging & Targeting Theranostics

On September 7, 2021 Telix Pharmaceuticals Limited (ASX: TLX, Telix, the Company) reported it has commenced a collaboration with Kettering Health (KH), a faith-based network of 13 hospitals, emergency centers, and outpatient facilities located in Southwest Ohio; headquartered at the Kettering Memorial Hospital in Kettering, Ohio, United States (Press release, Telix Pharmaceuticals, SEP 7, 2021, View Source [SID1234587333]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The parties have signed a Memorandum of Understanding ("MOU") formalising their intent to work together to foster late-stage clinical research into Telix’s investigational PSMA1-targeting radiopharmaceuticals, illuccix (Kit for the preparation of 68Ga-PSMA-11 injection, for diagnostic imaging with positron emission tomography, (PET) and Lu-177 PSMA (TLX591, for radioligand therapy), and to establish Kettering Health as a regional centre of excellence for PET Molecular Imaging (Ml) and Theranostics, with an initial focus on the diagnosis and treatment of prostate cancer.

The MOU outlines the principles of the collaboration between Kettering Health and Telix. The parties intend to develop binding agreements for each aspect of the collaboration, based on the principles set out in the MOU.

Telix and Kettering Health plan to work closely with multiple industry leaders, culminating in the rapid implementation of PET MI technologies (imaging and theranostics) into clinical services for patients in the region. The aim is to capitalize on the growing demand for PET MI, catalysed by the exponential growth of new radiopharmaceuticals in the short term, and over the longer-term, develop a continuous pipeline of new technologies for diagnosis and treatment of multiple diseases.

Dr Martin Satter, Senior Molecular Imaging Scientist at Kettering Health said, "We believe PET Molecular Imaging has the potential to quickly redefine, reimagine and reinvent the diagnosis and treatment of cancer, Alzheimer’s, Parkinson’s, cardiac and other diseases. This belief has evolved and crystalized over our 30-year history in PET MI, and our current re-commitment to this technology including our recent upgrades of a medical cyclotron, radiochemistry lab and clean room, as well as a digital PET/CT2 scanner.

"We are excited to work with Telix – a global leader in the field of radiopharmaceuticals and radioligand therapy to foster research and innovation in a non-academic setting. Telix shares our commitment to bring personalized medicine to our region through these disruptive technologies."

Dr Bernard Lambert, President of Telix Americas said, "This is a collaboration that brings together leading industry, technical, academic and clinical resources to further explore the potential of our PSMA-targeting radiopharmaceuticals. It reinforces Telix’s position as a leading innovator in this field, with a commitment to driving forward both clinical development alongside the supply chain, to support the commercialisation journey."

Therapeutic Solutions International Signs Memorandum of Understanding with Clinical Stage Immunotherapy Company Eutilogics, Inc. to Explore Augmentation of Synergies between StemVacs-V and TAST

On September 7, 2021 Therapeutic Solutions International, Inc., (OTC Markets: TSOI), reported the signing of a memorandum of understanding with immunotherapy company Eutilogics, Inc., the wholly owned subsidiary of clinical stage Korean company, Eutilex Co., Ltd., based on exploring synergies between technologies of both Companies (Press release, Therapeutics Solutions International, SEP 7, 2021, View Source [SID1234587349]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Eutilex has developed an autologous immunotherapy for tumors which unleash the endogenous ability of T cells to selectively kill tumor cells, even in solid tumors, which will be commercially developed in the US by Eutilogics. As the discoverer of CD137 (4-1BB) and AITR receptors, Eutilogics CEO, Dr. Byoung S. Kwon, is an internationally renowned expert of the immune system, and TAST is a globally competitive targeted cell therapy treatment, which is the result of the validation of decades of research and development.

Therapeutic Solutions International has recently filed an Investigational New Drug application for its StemVacs-V tumor-angiogenesis targeting immunotherapy in breast cancer. StemVacs-V has been demonstrated to induce immune responses to kill blood vessels that feed tumors. StemVacs-V has demonstrated superior tumor inhibition in comparison to other blood vessel targeting immunotherapies in animal models.

"Having collaborated with scientists from Therapeutic Solutions International for several years, we are eager to take our work to the next level through this memorandum of understanding formalizing our collaboration," said Dr. Byoung S. Kwon. "Given that Therapeutic Solutions International has synergistic expertise in cell therapy, we hope to advance more treatment options for patients, much faster."

"Eutilex has been a pioneer in creating novel immunotherapies that leverage the unique molecule 4.1 BB, which is one of the keys in creating an optimized T cell response against tumors. We hope to leverage this technology to kill tumor blood vessels, which appear to be more sensitive towards immunologically based targeting," said Timothy Dixon, President and CEO of Therapeutic Solutions International.

Galera to Present at Three Upcoming Investor Conferences in September

On September 7, 2021 Galera Therapeutics, Inc. (Nasdaq: GRTX), a clinical-stage biopharmaceutical company focused on developing and commercializing a pipeline of novel, proprietary therapeutics that have the potential to transform radiotherapy in cancer, reported that Mel Sorensen, M.D., President and Chief Executive Officer, will present at three upcoming virtual investor conferences in September (Press release, Galera Therapeutics, SEP 7, 2021, View Source [SID1234587530]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Presentation Details:

Event: H.C. Wainwright 23rd Annual Global Investment Conference
Date: Monday, September 13, 2021
Time: On-demand beginning at 7:00 a.m. ET

Event: Oppenheimer Fall Healthcare Life Sciences & MedTech Summit
Date: Tuesday, September 21, 2021
Time: 11:35 a.m. ET

Event: Cantor Fitzgerald Global Healthcare Conference
Date: Wednesday, September 29, 2021
Time: 10:00 a.m. ET

Live webcasts from the three presentations will be accessible from the Investors page of Galera’s website, investors.galeratx.com. Following the events, archived webcasts will be available on the Galera website for 30 days.

Orum Therapeutics to Present at Baird’s 2021 Global Healthcare Conference

On September 7, 2021 Orum Therapeutics, a biotechnology company pioneering the development of tumor-directed targeted protein degraders, reported that Sung Joo Lee, Ph.D., Founder and CEO of Orum Therapeutics, will present at Baird’s 2021 Global Healthcare Conference, on Tuesday, September 14th, 2021 at 10:50 a.m. ET (Press release, Orum Therapeutics, SEP 7, 2021, View Source [SID1234587285]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Ultragenyx to Present at Morgan Stanley Healthcare Conference

On September 7, 2021 Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE), a biopharmaceutical company focused on the development and commercialization of novel therapies for serious rare and ultra-rare genetic diseases, reported that Emil D. Kakkis, M.D., Ph.D., the company’s Chief Executive Officer and President will present at the Morgan Stanley 19th Annual Healthcare Conference on September 14, 2021 at 4:15 PM ET (Press release, Ultragenyx Pharmaceutical, SEP 7, 2021, View Source [SID1234587302]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The live and archived webcast of the presentation will be accessible from the company’s website at View Source The replay of the webcast will be available for 90 days.